Rhea Mae V.

Valles
BSN-III
Drug Study
Brand Name & Indication Mechanism of Action Dosage Adverse Reaction Nursing Consideration
Generic Name
Losartan Hypertension, Angiotensin II receptor Adult : PO HTN CNS: Dizziness, Monitor BP at drug
(Angiotensin II diabetic (type AT1) antagonist 50 mg once daily, insomnia, trough (prior to a
Antagonists ) nephropathy, acts as a potent may increase to headache. scheduled dose).
heart failure vasoconstrictor and 100 mg/day as GI: Diarrhea, Monitor drug
primary vasoactive single dose or in 2 dyspepsia. effectiveness, especially
hormone of the renin divided doses if Musculoskeletal: in African-Americans
angiotensinaldosterone needed. Patients Muscle cramps, when losartan is used as
system. w/ intravascular myalgia, back or leg monotherapy.
volume depletion: pain. Inadequate response may
Initial: 25 mg Respiratory: Nasal be improved by splitting
once daily. congestion, cough, the daily dose into twice-
upper respiratory daily dose.
infection, sinusitis. Lab tests: Monitor CBC,
electrolytes, liver &
kidney function with
long-term therapy.