NAME MECHANISM OF INDICATIONS CONTRAINDICATI COMMON SIDE NURSING

ACTION & RATIONALE ONS EFFECTS CONSIDERATIONS

Generic Name: Selectively blocks Acute treatment Concurrent use of other CNS: neuroleptic malignant Advise patient to
Ziprasidone serotonin and as monotherapy drugs that prolong QT syndrome, paresthesia, change position slowly
Brand Name: dopamine receptors of manic or interval, history of personality or speech to minimize
Geodon in the mesocortical mixed episodes arrythmia, disorder, suicidal ideation, orthostatic
Classification: tract of the CNS, associated with hypersensitivity to tremor hypotension.
Anti-psychotic thereby suppressing bipolar I disorder ziprasidone or its
Dosage: psychotic components, history of EENT: -Avoid alcohol, other
40mg symptoms prolonged QT interval, Abnormal vision, dry mouth CNS depressants,
Frequency: uncompensated heart OTC medications and
BID failure. GI: abdominal pain, herbal products unless
Route: anorexia approved by provider.
Oral
RESP: cough, pulmonary -Inform about need for
embolism, upper respiratory follow-up
tract infection psychotherapy, eye
exams and lab tests.

-Monitor serum
potassium and
magnesium prior to
and periodically
during therapy.
Generic Name: Considered to relate First-line Life-threatening Fatigue -Assess for mental
Biperiden to competitive treatment of tachycardia, Dizziness status.
Brand Name: antagonism of extrapyramidal Prostatic hypertrophy, Dyskinesia
Akineton acetylcholine at reactions induced Intestinal stenosis or Ataxia -Assess patient
Classification: cholinergic by antipsychotics. obstruction Anxiety response if
Anti-cholinergic receptors in the Restlessness anticholinergics are
Dosage: corpus striatum, Twitching given.
2mg 1 tab which the restores Skin rashes
Frequency: the balance. Confusion -Assess for tolerance
Once a day over long term
Route: therapy, dosage may
Oral have to be increased or
changed.

-Avoid activities that

require alertness, may
cause dizziness,
drowsiness and
blurring of vision.
Generic Name: Pharmacokinetics: It is used to treat Hypersensitivity, CNS: Neuroleptic malignant - Read ticket compare
Duloxetine A: Well absorbed depression and concurrent use of MAO syndrome, seizures, suicide with doctor's order and
Brand Name: after oral anxiety. inhibitors; uncontrolled thoughts, fatigue, have signed by head
Cymbalta administration. angle-closure drowsiness, insomnia, nurse.
Classification: D: unknown glaucoma, end-stage mania activation. dizziness - History:
Selective M&F: Mostly renal disease; chronic nightmares Hypersensitivity to
Serotonin, metabolized hepatic impairment or EENT: blurred vision, fluoxetine, impaired
Reuptake Inhibitor primarily by substantial alcohol use increased IOP hepatic or renal
Dosage: CYP2D6 and (increased hepatitis CV: hypertension function, diabetes
min-20mg CYPIA2 enzyme risk), lactation. GI: hepatotoxicity, mellitus. lactation,
max-60mg pathways decreased appetite, pregnancy, seizures
Frequency: Half-life: 12 constipation, dry mouth, - Physical: Weight.
OD highly(>90%) nausea, diarrhea, gastritis skin rash, lesions;
Route: protein bound vomiting. reflexes, affect; bowel
PO F&E: hypothermia sounds, liver
GU: Dysuria, abnormal evaluation, peripheral
orgasm, ED, Decreased perfusion; urinary
libido, urinary retention. output. ISTs, renal
Derm: Diaphoresis, pruritus, function tests - -
rash. Medical hand washing
Neuro: tremors should be done prior
Misc: Serotonin syndrome. to patient handling and
drug administration.
- Take baseline vital
signs. (TPRBP, Pain
score if applicable)
Generic Name: Binds to Indicated for the Hypersensitivity to this Dizziness, drowsiness, -Monitor BP, heart
Lozarepam stereospecific management of drug or any component lethargy, hangover, rate and rhythm,
Brand Name: benzodiazepine anxiety disorders of its formulation headache, mental respirations, airway
Ativan receptors on the or for the short- (cross-sensitivity with depression, blurred vision, integrity, and pulse
Classification: postsynaptic GABA term relief of the other benzodiazepines respiratory depression, oximetry during
Anxiolytic, (Gamma- symptoms of may exist); acute- constipation, diarrhea, procedure.
sedative-hypnotic Aminobutyric anxiety or anxiety narrow glaucoma; sleep nausea, vomiting,
Dosage: Acid) neuron at associated with apnea; severe hypotension, rashes -Monitor hepatic
1mg several sites within depressive respiratory renal, and
Frequency: the central nervous symptoms. insufficiency; hematopoietic
BID system, including pregnancy function periodically
Route: the limbic system, in patients receiving
Oral reticular formation. repeated or prolong
therapy.
Enhancement of the
inhibitory effect of
GABA on neural
excitability results
by increased
neuronal membrane
permeability to
chloride ions. This
shift in chloride
ions results in
hyperpolarization (a
less excitable state)
and stabilization.