ABSTRACT

DRUG UTILIZATION STUDY OF RAPID ACTING INSULIN IN PATIENTS

DIABETES MELLITUS TYPE 2 WITH CHRONIC KIDNEY DISEASE
(Research at Dr. Saiful Anwar Malang Hospital)

Putra Pratama Rahmadin(1),

Didik Hasmono(2), Naylis Syifa(3)
1,3
Pharmacy Departement, Health Science Faculty,
University of Muhammadiyah Malang, Malang, Indonesia
2
Pharmacy Faculty, University of Airlangga, Surabaya, Indonesia

Background: Utilization of Rapid-Acting Insulin as monotherapy or combination

with another insulin should be given to control blood glucose strictly in patients with
Type 2 Diabetes Mellitus with Chronic Kidney Disease, which can prevent and
improve the patients development of vascular complications.
Objectives: Studied the utilization of Rapid-Acting Insulin in patients Type 2
Diabetes Mellitus with Chronic Kidney Disease that includes dosage, frequency,
route and duration of therapy at Dr. Saiful Anwar Malang Hospital.
Methods: Observational study with retrospective data acquisition in patients Type 2
Diabetes Mellitus with Chronic Kidney Disease period January 1st 2014 December
31st 2015.
Results and Conclusion: Utilization of rapid-acting insulin single dose is 42 patients
(37%), the most utilizing is Novorapid 4-0-0 IU Sc is 7 patients (14%). Utilization
of combination rapid-acting insulin is 73 patients (63%), the most utilizing are
Novorapid 0-6-6 + Levemir 0-0-12 IU Sc are 2 patients (6%), Novorapid 6-6-6 +
Levemir 0-0-12 IU Sc are 2 patients (6%), Novorapid 0-4-4 + Levemir 0-0-14 IU
Sc are 2 patients (6%), Novorapid 4-0-4 + Levemir 0-0-14 IU Sc are 2 patients
(6%), Novorapid 4-4-4 + Levemir 0-0-14 IU Sc are 2 patients (6%) and
Novorapid 6-0-6 + Insulatard 0-0-10 IU Sc are 2 patients (6%).

Keywords: Rapid-Acting Insulin, Type 2 Diabetes, CKD