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Days 1 2 3 4 5 8 9 10 11 12 1 1 1 1 1 24 1 2 3 4 5 8 9 15 - 19 1 2 3 4 5 8 9 11 22 23
5 6 7 8 9
Dexamethasone oral (20 mg/m2/day)
Mitoxantrone IV (10 mg/m2)
Vincristine IV (1.5 mg/m2)
PEG-asparaginase IV (1000 mg/m2)
Age-adjusted intrathecal MTX
Cyclophosphamide IV (440 mg/m2)
Etoposide (100 mg/m2)
Cytarabine IV (3000 mg/m2 every 12h)
Metrotrexate IV (1000
Erwinase IM (20.000 U/m2)
Intrathecal MTX
Supervisor,
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