1300

A PPEND I X B
Pediatric Normal Laboratory Values
Dean B. Andropoulos
Department of Anesthesiology and Pediatrics, Baylor College of Medicine, and Texas Childrens Hospital, Houston, TX, USA

For conversion of conventional (US) units to SI units, see:
www.soc-bdr.org/rds/authors/unit_tables_
conversions_and_genetic_dictionaries/e5196/index_
en.html
Values are reference values from Texas Childrens Hospital
Clinical Laboratory, current as of August 2011. All practi-
tioners are urged to consult the normal laboratory values
for their local laboratory, as these may differ from those
listed below. They are also advised to continually check
for updated normal ranges.

Gregory's Pediatric Anesthesia, Fifth Edition. Edited by George A. Gregory, Dean B. Andropoulos.
2012 Blackwell Publishing Ltd. Published 2012 by Blackwell Publishing Ltd.
 Appendix B 1301

Test Reference range (United States/conventional units)

Albumin (CSF) 1030 mg/dL

Albumin (S, P)
Age g/dL
030 days 2.95.5
13 months 2.85.0
411 months 3.95.1
1 yr 3.75.5
Albumin (random urine) <37 mg/L or <3.7 mg/dL
Albumin/creatinine ratio (random urine) <16 mg/g
1-Antitrypsin(S)
Age mg/dL
01 yr 92282
14 yrs 94156
413 yrs 102159
>14 yrs 97203
-Fetoprotein (AFP) (S)
Adult <10 ng/mL
Birth Up to 86,000 ng/mL
1 month or less May be >10,000 ng/mL
23 months Up to 1000 ng/mL

Alanine aminotransferase (S, P)

Age M/F (U/L)
011 months 650
13 yrs 645
46 yrs 1025
79 yrs 1035
Male (U/L) Female (U/L)
1011 yrs 1035 1030
1213 yrs 1055 1030
1415 yrs 1045 630
1618 yrs 1040 635
19 yrs 2172 952

Alkaline phosphatase (S, P)

Age M/F (U/L)
05 days 110300
6 days11 months 110320
13 yrs 145320
46 yrs 150380
79 yrs 175420
Male (U/L) Female (U/L)
1011 yrs 135530 130560
1213 yrs 200495 105420
1415 yrs 130525 70230
1618 yrs 65260 50130
> 19 yrs 38126 38126

Ammonia (P)
Age mol/L
07 days 5494
830 days 4780
112 months 1547
115 yrs 2248
16 yrs 926
(Continued)
1302 Appendix B

Test Reference range (United States/conventional units)

Amylase (S, P) 30115 U/L

Amylase (U) timed 437 U/2 h
Amylase (U) random No reference range

Anticardiolipin IgG (S) <23.0 GPL

Anticardiolipin IgM (S) <11.0 MPL

Anti-Dnase-B
Age
05 yrs 1:60
618 yrs 1:170
19 yrs 1:85

Antistreptolysin-O (ASO) <250 IU/mL

Antithrombin (ATIII) (P) 85130%

Normal ranges for healthy full-term infants
Day 1 63% (3987%)
Day 5 67% (4193%)
Day 30 78% (48108%)
Day 90 97% (73121%)
Day 180 104% (84124%)

Aspartate aminotransferase (S, P)

Age M/F (U/L)
05 days 35140
6 days3 yrs 2060
46 yrs 1550
79 yrs 1540
Male (U/L) Female (U/L)
1011 yrs 1060 1040
1215 yrs 1540 1030
1618 yrs 1045 530
19 yrs 1759 1436

Bilirubin (S, P)
Premature (mg/dL) Full-term (mg/dL)
Age Total Total
Up to 23 h 18 26
2448 h 612 610
35 days 1014 48
1 month mg/dL
Bc conjugated <0.35
Bu unconjugated <1.0
Total 0.21.0

B-hydroxybutyrate (S, P) <0.30 mmol/L(12 h fast)

Blood gases
pH
Capillary/arterial
Age
Newborn 7.337.49
1 day 7.257.43
230 days 7.327.43
1 month 7.347.43
2 months1 yr 7.347.46
2 yrs
 Appendix B 1303

Test Reference range (United States/conventional units)

Male 7.357.45
Female 7.367.44
Venous
All ages 7.327.42
pCO2
Capillary/arterial
Age mmHg
01 month 2740
2 months1 yr 2641

2 yrs
Male 3646
Female 3343
Venous
All ages 4050

pO2 mmHg mmHg mmHg

Age Capillary Arterial Venous

01 yr 6070 6576 2540
2 yrs 8090 88105 4047
Oxygen saturation 85100%

B-type natriuretic peptide (BNP) (EDTA plasma) 0100 pg/mL

BUN see Urea nitrogen

Complement (CH50), total (S) 2346 CH50 U/mL

Complement C3,C4 (S)

Age C3 (mg/dL) C4 (mg/dL)
030 days 54128 828
1 month 60153 832
2 months 66134 1031
3 months 63179 943
4 months 66171 841
5 months 75176 1048
68 months 77170 1242
911 months 86179 1445
1 yr 83174 1039
2 yrs 78176 1241
34 yrs 89170 1436
57 yrs 90160 1436
89 yrs 92200 1245
10 yrs 86182 1751

C-reactive protein (CRP) <1.0 mg/mL

Ca2+(ionized) (WB)

Age mmol/L
030 days 0.901.45
15 months 0.951.50
6 months 1.101.30

Carboxyhemoglobin (WB) <1.5% of tHb

(Continued)
1304 Appendix B

Test Reference range (United States/conventional units)

Calcium (S)
Age mg/dL
011 months 8.010.7
13 yrs 8.79.8
411 yrs 8.810.1
1213 yrs 8.810.6
1415 yrs 9.210.7
16 yrs 8.910.7
Calcium (U) timed 42353 mg/24 h
Calcium (U) random No reference range

Ceruloplasmin (S)
Age mg/dL
01 month 325
111 months 1444
1 yr9 yrs 2351
10 yrs 1846

Chloride (S, P) 95105 mmol/L

Chloride (SWT) sweat test 6 months >6 months
Normal = 29 mmol/L Normal = 39 mmol/L
Intermediate = 3059 mmol/L Intermediate = 4059 mmol/L
Positive = 60 mmol/L Positive = 60 mmol/L
Chloride (CSF) 122132 mmol/L
Chloride (U) timed
Age mmol/24 h
011 months 210
115 yrs 1540
16 yrs 110250
Chloride (U) random No reference range

Cholesterol (S, P)
Age mg/dL
011 months 50120
1 yr 70190
215 yrs 135200
16 yrs 130200
Cholesterol, HDL (S, P)
Age Male (mg/dL) Female (mg/dL)
615 yrs 3875 3573
16 yrs 3064 3580
Cholesterol, LDL
Age Male (mg/dL) Female (mg/dL)
616 yrs 64130 60140
1718 yrs 63135 59141
1921 yrs 65145 60155
22 yrs 65161 62162

CO2 content (S, P)

Age mmol/L
015 yrs 2028
16 yrs 2535

Cold agglutinins (S) 1:40

Cortisol (S)
Age g/dL
17 days 211
112 months 2.823
 Appendix B 1305

Test Reference range (United States/conventional units)

116 yrs (8 am) 321

16 yrs (8 am) 819
(4 pm) 411

Creatine kinase (CPK) (S, P)

Age M/F (U/L)
03 yrs 60305
46 yrs 75230
79 yrs 60365
Male (U/L) Female (U/L)
1011 yrs 55215 80230
1213 yrs 60330 50295
1415 yrs 60335 50240
1618 yrs 55370 45230
19 yrs 55170 30135
Creatine kinase MB band (S, P) Normal: <5 ng/mL
Borderline: 510 ng/mL
Abnormal: >10 ng/mL
Creatinine (S, P) 0.121.06 mg/dL
Creatinine (U) timed 0.82.8 g/24 h
Creatinine (U) random <500 mg/dL
Creatinine clearance (U)
Age mL/min
030 days 2555
15 months 5090
611 months 75125
1 yr 90150

D-dimer (P)
Adult 0.40 g/mL FEU
Neonatal reference range from cord blood <3.40 g/mL FEU

Diluted Russell viper venom test (DRVVT) (P)

DRVVT S/C ratio <1.35
DRVVT result Negative

Factor 2 (P) 50150% normal activity

Factor 5 (P) 69132% normal activity
Factor 7 (P) 58150% normal activity
Factor 8 (P) 47169% normal activity
Factor 9 (P) 67141% normal activity
Factor 10 (P) 65142% normal activity
Factor 11 (P) 48139% normal activity
Factor 12 (P) 41140% normal activity

Ferritin (S)
Age ng/mL
1 day6 months 36391
712 months 36100
15 yrs 3684
>6 yrs
Male 36311
Female 3692

Fibrinogen (P)
Adult 220440 mg/dL
Neonatal reference range from cord blood 135283 mg/dL
(Continued)
1306 Appendix B

Test Reference range (United States/conventional units)

Follicle-stimulating hormone (FSH) (S)

Male (mIU/mL) Female (mIU/mL)
Infants <10 <50
Prepubertal <7 <11
Adult 1.617.2 0.415.1
Follicular/luteal 3.516.9
Midcycle 11.932.7

Fibrin split product (FSP) (P) 1:2 Dilution = Negative (<5 g/mL)

-Glutamyl transferase (GGT) (S, P)

Age M/F (U/L)
05 days 34263
6 days2 months 10160
311 months 1182
13 yrs 1019
46 yrs 1022
79 yrs 1325
Male (U/L) Female (U/L)
1011 yrs 1730 1728
1213 yrs 1744 1425
1415 yrs 1233 1426
1618 yrs 1134 1128
19 yrs 1078 1078

Glucose (S, P)(WB): glucose conversion factor for

mg/dL to mmol/L: divide mg/dL value by 18
Age mg/dL
112 h 3065
1223 h 3080
1 day 5058
2 days 5860
3 days 70110
Glucose (CSF) 5070% of serum glucose
Glucose (U) timed <500 mg/24 h
Glucose (U) random <30 mg/dL

Glycosylated hemoglobin (WB) Without diabetes 4.06.8%

With diabetes 6.022.0%

Haptoglobin (S)
Age mg/dL
01 yr 34175
23 yrs 30140
45 yrs 30191
6 yrs 35181

Human chorionic gonadotropin (HCG) (S) Postconception normals (mIU/mL)

1 Week = 550
2 Weeks = 401,000
3 Weeks = 1005000
4 Weeks = 60010,000
56 Weeks = 1500100,000
78 Weeks = 16,000200,000
Second trimester = 24,00055,000
Third trimester = 600048,000
 Appendix B 1307

Test Reference range (United States/conventional units)

Hematocrit (B)
Age %
030 days 4470
1 month 3242
26 months 2941
7 months2 yrs 3339
36 yrs 3440
712 yrs 3545
1318 yrs/female 3645
1318 yrs/male 3749
19 yrs/female 3646
19 yrs/male 4153

Hemoglobin (B)
Age g/dL
030 days 15.022.0
1 month 10.514.0
26 months 9.513.5
7 months2 yrs 10.514.0
36 yrs 11.514.5
712 yrs 11.515.5
1318 yrs/female 12.016.0
1318 yrs/male 13.016.0
19 yrs/female 12.016.0
19 yrs/male 13.517.5

Hemoglobin fractionation, HPLC A A2 F

(WB)
Age (%) (%) (%)
030 days 1035 6590
13 months 3050 5070
45 months >90 <4 <10
6 months >90 <4 3

Heparin level, unfractionated (P)

Treatment 0.350.7 U/mL

Hexagonal phase phospholipid neutralization test

Staclot Diff Tube 1Tube 2 <8.0 sec
Staclot result Negative

Homocysteine
Age M/F (mol/L)
2 months10 yrs 3.38.3
1115 yrs 4.710.3
1618 yrs 4.711.3
Male Female
19 yrs 5.916.0 3.420.4

Immunoglobulin E (IgE) (S)

Age IU/mL
01 yrs <15
15 yrs <60
69 yrs <90
1015 yrs <200
16 yrs <100
Immunoglobulin G (IGG) (CSF) 0.45.2 mg/dL
(10% of total protein)
(Continued)
1308 Appendix B

Test Reference range (United States/conventional units)

IGG subclasses (S) IgG1 IgG2 IgG3 IgG4

Age (mg/dL) (mg/dL) (mg/dL) (mg/dL)
01 month 2401060 87410 1455 455
14 months 180670 38210 1470 336
46 months 180700 34210 1580 323
612 months 200770 34230 1597 343
11.5 yrs 250820 38240 15107 362
1.52 yrs 290850 45260 15113 379
23 yrs 320900 52280 14120 3106
34 yrs 350940 63300 13126 3127
46 yrs 3701000 72340 13133 3158
69 yrs 4001080 85410 13142 3189
912 yrs 4001150 98480 15149 3210
1218 yrs 3701280 106610 18163 4230
18 yrs 4901140 150640 20110 8140

International normalized ratio (INR) (P)

Adult 0.81.2
Neonatal reference range from cord blood 1.01.4

Immunoglobins (S) IgG IgA IgM

Age (mg/dL) (mg/dL) (mg/dL)
030 days 252909 0.8350 1880
1 month 207904 245 1596
2 months 177583 543 2282
3 months 196560 469 2593
4 months 173817 780 3099
5 months 216706 765 3294
68 months 218907 1085 31116
911 months 3461217 13100 40159
1 yr 4251054 13116 44155
2 yrs 4421139 21150 43184
34 yrs 4641240 22146 40180
57 yrs 6351284 32191 44190
89 yrs 6101577 42223 48222
10 yrs 6411353 66295 40180

Iron, total (S, P) 55150 g/dL

Lactate (P, WB, CSF) Mmol/L

Plasma (venous) 0.22.0
Plasma (arterial) 0.30.8
CSF 0.62.2
Whole blood 0.21.7

Lactate dehydrogenase (LDH) (S, P)

Age M/F (U/L)
05 days 9342150
6 days3 yrs 500920
46 yrs 470900
79 yrs 420750
Male (U/L) Female (U/L)
1011 yrs 432700 380770
1213 yrs 470750 380640
1415 yrs 360730 390580
1618 yrs 340670 340670
19 yrs 313618 313618
 Appendix B 1309

Test Reference range (United States/conventional units)

LDH (CSF)
Age
030 days 2.38.4 U/L
1 month Approximately 10% of serum value

Lovenox level (P)

Prophylactic 0.200.40 U/mL
Treatment: 0.501.00 U/mL

Luteinizing hormone (S)

Male (mIU/mL) Female (mIU/mL)
Infants <3 <3
Prepubertal <7 <7
Adult 0.910.6
Follicular 1.111.1
Midcycle 17.572.9
Luteal 0.415.1
Postmenopausal 6.846.6

Lipase (S, P)
Age U/L
09 yrs 25120
1013 yrs 15110
1418 yrs 25110
19 yrs 23300

Magnesium (S, P)
Age mg/dL
06 days 1.22.6
730 days 1.62.4
1 month1 yr 1.62.6
25 yrs 1.52.4
69 yrs 1.62.3
1013 yrs 1.62.2
14 yrs 1.52.3
Magnesium (U) timed 12.4191.9 mg/24 h
Magnesium (U) random No reference range

Mean corpuscular hemoglobin (MCH)

Age pg
030 days 33.039.0
1 month 28.040.0
26 months 25.035.0
7 months2 yrs 23.031.0
36 yrs 25.030.0
712 yrs 26.030.0
1318 yrs 26.032.0
>19 yrs 27.031.0
Mean corpuscular hemoglobin concentration (MCHC)
Age g/dL
030 days 32.036.0
1 month 33.038.0
26 months 28.036.0
7 months2 yrs 30.034.0
36 yrs 32.036.0
712 yrs 32.036.0
(Continued)
1310 Appendix B

Test Reference range (United States/conventional units)

1318 yrs 32.036.0

>19 yrs 32.036.0

Mean corpuscular volume (MCV)

Age fL
030 days 86.0115.0
1 month 72.088.0
26 months 72.082.0
7 months2 yrs 76.090.0
36 yrs 76.090.0
712 yrs 76.090.0
1318 yrs 78.095.0
>19 yrs 78.0100.0

Methemoglobin (WB) <2% of tHb

Microalbumin (random urine) 037 mg/L or 03.7 mg/dL

Microalbumin (U) timed <20 g/min
<30 mg/24 h

Osmolality (S, P) 275295 mOsm/kg H2O

Osmolality (U) 3001000 mOsm/kg H2O

Phosphorus, inorganic (S, P)

Age mg/dL
Premature 5.68.0
Term 5.07.8
03 months 4.88.1
411 months 3.86.7
14 yrs 3.56.8
57 yrs 3.16.3
811 yrs 3.06.0
1216 yrs 2.55.0
17 yrs 2.34.8
Phosphorus, inorganic (U) timed 0.91.3 g/24 h
Phosphorus, inorganic (U) random No reference range

Plasma hemoglobin (P) 4 mg/dL

Plasma hemoglobin (U) None detected

Plasminogen activity 56148%

Platelet count (B) 150,000450,000/ L

Platelet function assay (WB)
Collagen/epinephrine 84183 sec
Collagen/ADP 69126 sec

Potassium (S, P)
Age mmol/L
030 days 4.57.0 (venous or arterial)
4.57.5 (heel stick)
12 months 4.06.2
311 months 3.75.6
1 yr 3.55.5
Potassium (U) timed 4080 mmol/24 h
Potassium (U) random No reference range
Potassium (WB)
Age mmol/L
Premature 4.57.0
 Appendix B 1311

Test Reference range (United States/conventional units)

011 months 5.05.7

1 yr 3.55.5

Pre-albumin (S)
Age mg/dL
06 days 420
741 days 825
42 days 1844

Prolactin (S) ng/mL

Newborn >10 x adult levels
Nursing female <40
Follicular female <23
Luteal female 540
Pregnancy
1st trimester <84
2nd trimester 18306
3rd trimester 34386

Protein, total (S, P)

Age g/dL
030 days 4.47.6
13 months 4.27.4
411 months 5.67.2
1 yr 6.08.0
Protein (CSF)
Age mg/dL
Premature 40300
030 days <100
1 month 1545
Protein C (P) 80175%
Normal ranges for healthy full-term infants:
Day 1 35% (1753%)
Day 5 42% (2064%)
Day 30 43% (2165%)
Day 90 54% (2880%)
Day 180 59% (3781%)
(Am J Pediatr Hematol Oncol 1990;12:95104)
Please note that these ranges were not established using
the current reagent and analyzer at TCH Coagulation Lab
Protein S (P) 51157%
Normal ranges for healthy full-term infants
Day 1 36% (1260%)
Day 5 50% (2278%)
Day 30 63% (3393%)
Day 90 86% (54118%)
Day 180 87% (55119%)
(Am J Pediatr Hematol Oncol 1990;12:95104)
Please note that these ranges were not established using
the current reagent and analyzer at TCH Coagulation Lab
Protein, total (U) timed 28141 mg/24 h
Protein, total (U) random No reference range

Prothrombin time (PT) (P)

Adult 12.215.5 sec
Neonatal reference range from cord blood 12.916.9 sec
(Continued)
1312 Appendix B

Test Reference range (United States/conventional units)

Partial thromboplastin time (PTT) (P)

Adult 26.535.5 sec
Neonatal reference range from cord blood 28.753.7 sec

Red blood cell count (RBC) (B)

Age 106/L
030 days 4.16.7
1 month 3.05.4
26 months 2.74.5
7 months2 yrs 3.75.3
36 yrs 3.95.3
712 yrs 4.05.2
1318 yrs /female 4.15.1
1318 yrs /male 4.55.3
19 yrs/female 4.25.4
19 yrs/male 4.76.0

Red cell distribution width coefcient of variation (RDWCV)

Age %
030 days 13.018.0
1 month 13.018.0
26 months 13.018.0
7 months2 yrs 11.516.0
36 yrs 11.515.0
712 yrs 11.514.0
1318 yrs 11.514.0
>19 yrs 11.514.0

Red cell distribution width standard deviation (RDWSD)

Age fL
030 days 38.549.0
1 month 38.549.0
26 months 38.549.0
7 months2 yrs 38.549.0
36 yrs 38.549.0
712 yrs 38.549.0
1318 yrs 38.549.0
>19 yrs 38.549.0

Reticulocyte count % (B)

Age %
02 days 3.07.0
34 days 1.03.0
>4 days 0.51.5
Reticulocyte count absolute (B)
Age 106/L
02 days 0.1400.220
34 days 0.0400.110
>4 days 0.0200.080

Reticulocyte hemoglobin content (B)

Age pg
<2 years 24.535.2
2 yrs 27.135.4

Sedimentation rate (B) 020 mm/h

 Appendix B 1313

Test Reference range (United States/conventional units)

Sirolimus/rapamycin (P) 312 ng/mL

Sodium (S, P) (WB)

Age mmol/L
Premature 132140
011 months 133142
1 yr 136145
Sodium (U) timed
Age mmol/24 h
011 months 0.33.5
115 yrs 40180
16 yrs 80200
Sodium (U) random No normals

Free thyroxine (T4) (S) 1.02.5 ng/dL

T4 (S)
Age g/dL
Cord blood 8.013
07 days 11.524
8 days4 yrs 7.015
5 yrs9 yrs 6.413.3
10 yrs 5.012
Free thyroxine index (T7) (S)
Age
07 days 9.126.6
8 days4 yrs 5.516.6
59 yrs 5.114.7
10 yrs 4.013.3

Thromboelastogram (TEG ) with kaolin

Reaction time 4.411.0 min
Angle 49.174.7
Max amplitude 53.670.3 mm
Fibrinolysis 0.07.5%
Clot strength 5.211.3
Thrombin time 15.019.0 sec

Thyroid stimulating hormone (TSH) (S)

Age IU/mL
Cord blood 322
07 days <40.00
8 14 days <25.00
15 days 0.325.00

Tri-iodothyronine (T3) uptake (S) 2535%

Age ng/dL
Cord blood 3070
07 days 65275
8 days9 yrs 90260
1014 yrs 80210
15 yrs 115195

Transferrin (S) 169300 mg/dL

Transferrin saturation (S)
Age %
011 yrs 1539
(Continued)
1314 Appendix B

Males 1217 yrs 1644

Females 1217 yrs 1144
Males >18 yrs 2152
Females >18 yrs 1144

Triglycerides (S, P) 20150 mg/dL

Troponin I (S, P) <0.15 ng/mL

Urea nitrogen (S, P)

Age mg/dL
01 yr 828
215 yrs 525
16 yrs 520
Urea nitrogen (U) timed 1220 mg/24 h
Urea nitrogen (U) random No reference range

Uric acid (S, P) 2.06.2 mg/dL

Uric acid (U) timed 250750 mg/24 h
Uric acid (U) random No reference range

Urinalysis (U)
Specic gravity 1.0011.035
pH 49
Protein Neg
Glucose Neg
Ketone Neg
Bilirubin Neg
Urobilinogen <2.0
WBC 04/HPF
RBC 04/HPF
EPI (epithelial cells) 04/LPF

Von Willebrand ristocetin coactor activity (P) 48142%

Von Willebrand factor antigen (P) 56176%

White blood cell count (WBC) (B)

Age 103/L
030 days 9.134.0
1 month 5.019.5
211 months 6.017.5
16 yrs 5.014.5
712 yrs 5.014.5
1318 yrs 4.513.5
19 yrs 4.511.0

Age Seg (%) Band (%) Lymphs (%) Monos (%) EOS (%) BASO (%) ANC
030 days 3267 08 2537 09 02 01 6.023.5
1 month 2046 04.5 2884 07 03 01 1.09.0
211 months 2048 03.8 3488 05 03 01 1.08.5
16 yrs 3771 01.0 1767 05 03 01 1.58.0
712 yrs 3376 01.0 1561 05 03 01 1.58.0
1318 yrs 3376 01.0 1555 04 03 01 1.88.0
19 yrs 3376 00.7 1454 04 03 01 1.87.7

A, arterial; ADP, adenosine diphosphate; ANC, absolute neutrophil count; B, blood; band, banded neutrophils; BASO, basophils; C, capillary; CSF, cerebro-
spinal uid; EOS, eosinophils; F, female; FEU, brinogen equivalent units; GPL, gG phospholipid units/mL; HPF, high power eld; IU, international units;
lymphs, lymphocytes; LPF, low power eld; M, male; monos, monocytes; MPL, IgM phospholipid units/mL; P, plasma; S, serum; seg, segmented neutrophils;
SWT, sweat; U, urine; WB, whole blood.