The pineal gland, a structure about the size of a pea, is located
slightly above and behind the hypothalamus. It receives information via the thalamus from the eyes about light and dark cycles. It is involved in rhythmic behavior, such as sleep cycles for humans, but it is much more complicated in animals. For example, the pineal gland is crucial in helping birds decide when it is time to fly south for the winter. The pineal gland secretes the hormone melatonin, a modified amino acid that is derived from the neurotransmitter serotonin. Melatonin is released at night and acts within the brain to affect the cyclic behaviors. During winter, the length of the dark period increases, so more melatonin is released. This release connects daily cycles with seasonal cycles. Humans, however, do not have seasonal behaviors like animals that reproduce only at certain times of the year. The significance of melatonin and the pineal gland in humans is not clear. Many people believe that the body produces less melatonin as it ages and that this is one of the causes of aging. Some people use over-the-counter preparations of melatonin to fight jetlag and insomnia because it helps adjust the bodys sleep-wake cycle. Scientists are fairly certain that melatonin levels are involved in seasonal affective disorder (SAD), a condition that can be debilitating. For some people, the reduced amount of daylight during winter produces a craving for carbohydrates and causes lethargy and sometimes depression. SAD is often treated by exposing the sufferer to elevated levels of full-spectrum lightlight that has all of the wavelengths of sunlight (red to violet). Regular artificial lights do not have all of the wavelengths. Some individuals may be given melatonin and antidepressants as well.
From : The Endocrine System.2009. Rushton,Lynette.Infobase Publishing
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