Chapter 6 Materials and instruments

6. MATERIALS AND INSTRUMENTS

6.1. DRUG:

ADAPALENE: Gift sample from Abbott Healthcare Pvt. Ltd.

Mumbai, India.

6.2. MATERIALS AND CHEMICALS:

Table 6.1: List of materials and chemicals

S. Name of materials Manufacturer/ Supplier

No.
1. Span60 Loba Chemie Pvt Ltd.
Mumbai, India
2. Cholesterol Loba Chemie Pvt. Ltd.
Mumbai, India
3. Ethyl Alcohol Jiangsu Huaxi Int. Trade Co.
Ltd Made in China
4. Acetone Sigma-Aldrich, Mumbai,
India.
5. Sigma-Aldrich, Mumbai,
DMSO India
6. Anaesthetic ether Rachana Ether India Pvt.
Ltd, Nashik, India.
7. Triethanolamine Merck Ltd. Mumbai, India.
8. KBr S.D. Lab Chem. Centre,
Mumbai, India.
9. Dialysis membrane Sigmma-Aldrich chemical
(MW 12,000 cut off) Pvt. Ltd, Bang, India
10. Glycerine S.D. Lab Chem. Centre,
Mumbai, India.
11. Propylene glycol S.D. Lab Chem. Center,
Mumbai, India

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Chapter 6 Materials and instruments

12. Methylparaben S.D. Lab Chem. Center

13. Propylparaben S.D. Lab Chem. Centre,
Mumbai, India.
14. Carbopol 934 S.D. Lab Chem. Centre,
Mumbai, India.
15 Stearic acid S.D. Lab Chem. Centre,
Mumbai, India.
6.3 INSTRUMENTS:

Table 6.2: List of instruments

S. Name of instrument/ Make and Model

No. Equipment
1. UV-visible Jasco V-630, Japan.
spectrophotometer
2. FTIR Jasco 5300, Japan.
5. pH meter Toshniwal Process
instruments Pvt. Ltd, India.
6. Lyophilizer Labconco, USA.
7. Hot air oven Kumar Industries, India.
8. Centrifuge Beckman Coulter, Allegra
TM64R centrifuge, USA.
9. Rheometer Lund, Sweden
10. Malvern Mastersizer Hydro 2000SM, Malvern
particle size analyser Instruments, Malvern UK.
11. Optical Microscopy Nikon
12. DSC Mettler-Toledo DSC 821e
instrument equipped with an
intracooler (Mettler- Toledo,
Switzerland).
13. Bath sonicator Model- D-Compaq
14. Dissolution apparatus Lab India DS-8000,
Thane, India.

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Chapter 6 Materials and instruments

15. Hot plate META- LAB Mumbai,

India.
16. Stability chamber Thermolab, Mumbai, India.

6.4 SOFTWARES:-

1. Malvern Software Ver. 5.2 for particle size data

acquisition and processing.
2. Jasco spectra manager Ver. 2 for data acquisition and
processing obtained by FTIR, UV.
3. Design expert Ver.9.0

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