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Hydro Gel PDF
Hydro Gel PDF
Original Russian Text V.Yu. Baranovskii, V.G. Ganev, V.B. Petkova, Kh.Ch. Voicheva, M.V. Dimitrov, 2012, published in Kolloidnyi Zhurnal, 2012, Vol. 74, No. 6, pp. 675679.
AbstractIR spectroscopy and viscometry data have shown that poly(acrylic acid) and poly(methacrylic
acid) form complexes with agaragar in aqueous solutions as they do with other polysaccharides. The poly
acidagaragar complexes are typical hydrogels. The swelling index of hydrogels based on the poly(meth
acrylic acid)agaragar complex has been found to be markedly lower than that of poly(acrylic acid)agar
agar complex. The hydrogels based on the complex of crosslinked poly(acrylic acid) with agaragar can be
of practical interest as polymeric carriers for drugs.
DOI: 10.1134/S1061933X12060026
OH O
OH
CH2 H CH2 H H
OH O O
OH H O H O
CH2 H CH2 H H O 1
O
O H O 1 O 3 H OH 1
4 H
H OH
O H H H
O 4 O
3 H OH 1 H
OH
H H H
AA dissolves in water at 8385C with the forma Being a polysaccharide, AA must also form com
tion of a true solution. Subsequent cooling of a solu plexes with PAA and PMAA. However, there are no
tion with a concentration above 0.5% to 3540C data in the literature on the interaction of AA with the
gives rise to a hydrogel. above polyacids in aqueous solutions. Therefore, the
The sources of AA are red and brown see algae; i.e., goal of this work is to study the complexation of AA
AA is a renewable natural substance. with PAA and PMAA in aqueous media.
By its chemical structure, AA belongs to the class of
polysaccharides. There are numerous reports devoted EXPERIMENTAL
to the investigation of the complexation of polysac
charides with polycarboxylic acids, namely, PAA and PMAA were obtained by heterogeneous
poly(acrylic acid) (PAA) and poly(methacrylic acid) polymerization of the corresponding monomers in
(PMAA), in aqueous solutions (see, e.g., [115]). Var toluene under nitrogen at 60C using AIBN as an ini
ious cellulose derivatives, such as methyl [15], tiator. Residual monomers were washed off with tolu
hydroxyethyl [68], hydroxypropyl [913], and ene. The resulting polyacids were dried in vacuum at
hydroxypropylmethylcellulose [14, 15], are mainly 70C to a constant weight. The molecular masses of
used as polysaccharides. The physicochemical proper the polymers thus obtained were determined by vis
ties of the resulting complexes have been studied as cometry. For PAA, [] = (1.05 103) 0.54 in 2N
functions of medium pH and temperature, reagent NaOH at 25C [16] and, for PMAA, [] = (6.6
concentrations, and ionic strength of solutions. In 10 4)M 0.5 in 0.002 N HCl at 30C [17]. According to
most cases, the complexes have a nonstoichiometric the viscometry data, = 2.3 105 and = 9 104
composition. for PAA and PMAA, respectively.
645
646 BARANOVSKII et al.