Sequential Bonferroni Sequential Bonferroni

Statistics-speak:

normal significance level = 0.05

smallest P-value: 1 = /k
_ next smallest P-value: 2 = /(k-1)
_ next smallest P-value: 3 = /(k-2)
_ stop at first non-significant result (using the new,
calculated )

normal significance level = 0.05

1. Rank significance values from smallest to largest, i.e.

P-value
0.00001
0.00099
0.00300
0.03500
0.05000
0.06000
0.13000

2. Count the number of tests

P-value test
0.00001 1
0.00099 2
0.00300 3
0.03500 4
0.05000 5
0.06000 6
0.13000 7

3. Put the number of tests in inverse order

P-value test inverse

0.00001 1 7
0.00099 2 6
0.00300 3 5
0.03500 4 4
0.05000 5 3
0.06000 6 2
0.13000 7 1
4. Divide the desired significance level by the inverse

P-value test inverse Bonferroni corrected P-value

0.00001 1 7 0.05/7=0.007143
0.00099 2 6 0.05/6=0.00833
0.00300 3 5 0.05/5=0.01
0.03500 4 4 0.05/4=0.0125
0.05000 5 3 0.05/3=0.016667
0.06000 6 2 0.05/2=0.025
0.13000 7 1 0.05/1=0.05

5. The first three P-values are significant, as P-value<Bonferroni corrected P-

value