For the same reasons that we concluded the pyloric action was motivated locally

through duodenal stimulation by chemical action, we conclude that this same

mechanism is influenced by physical stimuli as represented by changes in
osmotic pressure away from isotonicity. Gastric emptying time alone cannot be
used as an index of pyloric function when considering osmotic tension of agents
given by mouth because of the migration of fluid which takes place through the
stomach wall when the test meals are not isotonic.

We should again like to draw attention to the necessity of considering the type
of test meal when measureing gastric motility. Roentgoenologists, especially,
must realize that no comparison of gastric motor data can be possible, if the test
meals vary either in chemical or physical composition.

What is bbb

Blood brain barrier

a filtering mechanism of the capillaries that carry blood to the brain and spinal cord tissue,
blocking the passage of certain substances.
the BBB significantly impedes entry from blood to brain of virtually all molecules, except those that are
small and lipophilic or those that enters the brain through an active transport mechanism, particularly
with essential nutrients, precursors, and cofactors.