Schematic Diagram of Stroke

Due to thrombosis or embolism, some Impaired cerebral tissue perfusion

neurons die because of lack of oxygen and (Hemorrhagic)
nutrients

Infarction of the Cerebral Vessels

known as Stroke

Tissue injury triggers an Space- occupying blood clots

inflammatory response put more pressure on the
which increases intracranial brain tissues.
pressure

The injury disrupts The regulatory mechanisms

metabolism leading to of the brain attempt to
changes in ionic transport, maintain equilibrium by
localized acidosis, and free increasing BP and ICP.
radical formation

Calcium, sodium, and water The ruptured cerebral vessels

accumulate in the injured may constrict to limit blood
cells and excitatory loss however; this vasospam
neurotransmitters are will result to further ischemia
released and necrosis of brain tissues.

Continued cell cellular injury

and swelling both occurs
resulting to further cell
damage

Brain Death