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  • Risk Factors and Symptoms of Ovarian Cancer

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    GinoTeves
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    This figure outlines the pathophysiology and progression of ovarian cancer. It shows that risk factors like age, diet, family history and medical conditions can lead to increased cellular proliferation and decreased apoptosis in the ovaries, resulting in ovarian cancer. The cancer then spreads locally through direct exfoliation in the peritoneum causing symptoms like pelvic discomfort, bloating and gastrointestinal issues. As it progresses, mucin 16 shedding and ascites formation increase the tumor marker CA 125 and abdominal girth.

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    Ovarian CA Patho.docx

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    This figure outlines the pathophysiology and progression of ovarian cancer. It shows that risk factors like age, diet, family history and medical conditions can lead to increased cellular proliferation and decreased apoptosis in the ovaries, resulting in ovarian cancer. The cancer then spreads locally through direct exfoliation in the peritoneum causing symptoms like pelvic discomfort, bloating and gastrointestinal issues. As it progresses, mucin 16 shedding and ascites formation increase the tumor marker CA 125 and abdominal girth.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    15 views1 page

    Risk Factors and Symptoms of Ovarian Cancer

    Uploaded by

    GinoTeves
    This figure outlines the pathophysiology and progression of ovarian cancer. It shows that risk factors like age, diet, family history and medical conditions can lead to increased cellular proliferation and decreased apoptosis in the ovaries, resulting in ovarian cancer. The cancer then spreads locally through direct exfoliation in the peritoneum causing symptoms like pelvic discomfort, bloating and gastrointestinal issues. As it progresses, mucin 16 shedding and ascites formation increase the tumor marker CA 125 and abdominal girth.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    Age

    Diet
    Family History
    Nulliparity
    Infertility
    Endometriosis
    K-ras Mutations
    BRCA 1/2 mutations
    HNPCC/Lynch Syndrome

    Increased Cellular Proliferation Decreased rate of apoptosis

    Ovarian Cancer

    Direct exfoliation
    Local
    throughout
    compression
    peritoneum

    Mucin 16
    pelvic discomfort bloating heartburn nausea
    shedding

    Increased
    urinary
    frequency/dysuria
    constipation early satiety indigestion CA 125

    abdominal pain constipation


    Ascites

    increased
    abdominal girth

    Figure 1. The Pathophysiology of Ovarian Cancer

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