ASEPRITE quick reference v0.9.

3
SPRITE EDITOR
Drawing Selection
Left button » Draw with FG color Ctrl+A » Select all
Right button » Draw with BG color Ctrl+D » Deselect
Alt+Left button » Pick the FG color Ctrl+Shift+D » Reselect (if you have deselected)
Alt+Right button » Pick the BG color Ctrl+Shift+I » Invert selected region
X key » Switch FG & BG colors Transformation (move/scale/rotate selection)
Zoom Shift » Lock X/Y Axis (when move)
1, 2, 3, 4, 5 or 6 » Change the zoom Alt » Snap to grid (when move)
Mouse wheel » More (up) or less (down) zoom Shift » Angle snap (when rotate)
Scroll Shift » Square aspect (when scale)

Middle button » Move scroll View

Space bar+Left button » Move scroll Tab key » Switch between Sprite & Animation Editor
Change Color F4 » Palette Editor

Alt+Mouse wheel » Displace Foreground color in color-bar F8 » Preview

Alt+Shift+Mouse wheel » Displace Background color in color-bar Grid

Change Frame Shift+G » Show/hide grid

Ctrl+Mouse wheel (up) » Next frame Shift+S » Snap to grid (on/off)

Ctrl+Mouse wheel (down) » Previous frame

Move Cel
Ctrl+Left button » Move cel's position (x, y)
Tools
C » Show/Hide the Tools Configuration dialog ANIMATION EDITOR (TAB key)
M » Rectangular Marquee
In Layers
Shift+M » Elliptical Marquee
Left button » Select the layer as the current layer
Q » Lasso
Right button » Show layer popup menu
Shift+Q » Polygonal Lasso
Drag & drop w/Left button » Move a layer after other layer
W » Magic Wand
B » Pencil In Frames
Shift+B » Spray Left button » Frame properties (duration in msecs)
Right button » Show frame popup menu
E » Eraser (Left button)
Drag & drop w/Left button » Move a entire frame (all cels) before other frame
Replace FG with BG color (Right button)
I » Eyedropper tool In Cels
H » Hand tool (to move scroll) Right button » Show cel popup menu
V » Move (work-in-progress) Drag & drop w/Left button » Move cel to other layer and/or frame
G » Paint Bucket Drag & drop w/Right button » Move or Copy cel to other layer and/or frame
L » Line Selection Tools (Marquee, Lasso, etc.)

Shift+L » Curve
U » Rectangle ANIMATION CONTROL
Shift+U » Ellipse
Enter » Play animation, then:
D » Contour
Enter » Stop playback in current frame
Shift+D » Polygon
Escape or right-click » Stop & return to the original frame
R » Blur / Jumble
Left arrow » Previous frame
Drawing with box-like tools (line, rectangle, ellipse) Right arrow » Next frame
Shift » Square aspect / angle snap
Home key » Jump to first frame
Ctrl » From center
End key » Jump to last frame
Editing P » Frame properties (e.g.: milliseconds of duration)
Ctrl+Z » Undo Alt+N » Create a new frame
Ctrl+R » Redo
Ctrl+X » Cut selected region in clipboard
Ctrl+C » Copy selected region in clipboard
LAYERS NAVIGATION
Ctrl+V » Paste from clipboard Up arrow » Select next layer in the stack (more in the front)
Del or Backspace » Clear selected region Down arrow » Select previous layer in the stack (more in the back)