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JIndianSocPeriodontol144279-4756864 131248 PDF
JIndianSocPeriodontol144279-4756864 131248 PDF
147]
Case Report
Management of amlodipine-induced
gingival enlargement: Series of three
cases
Amit Kumar Srivastava, Debabrata Kundu, Prasanta Bandyopadhyay,
Asit Kumar Pal
Abstract:
Department of Gingival enlargement is one of the side effects associated with certain drugs. Amlodipine, a calcium channel
Periodontics, blocker, used as antihypertensive drug has been found associated with gingival hyperplasia. This case series
Dr. R. Ahmed presents diagnosis and management of amlodipine-induced gingival hyperplasia. Amlodipine-induced gingival
enlargement was diagnosed and managed by thorough scaling and root planning. Drug substitution and surgical
Dental College &
intervention was performed in first two cases. The pathogenesis of gingival enlargement is uncertain and the
Hospital, Kolkata, treatment is still largely limited to the maintenance of an improved level of oral hygiene and surgical removal of
West Bengal, India the overgrown tissue. Several factors may influence the relationship between the drugs and gingival tissues as
discussed by Seymour et al. Meticulous oral hygiene maintenance, switchover to alternative drug, professional
scaling and root planning and surgical excision of enlarged gingival tissue may help overcome the effect of
these drugs.
Key words:
Calcium channel blocker, drug-induced gingival overgrowth, gingivectomy
a a
b b
c c
Figure 2: Case 2 — (a) intraoral picture at first visit (b) ten weeks after phase-1
therapy (c) nine-month postoperative view
Figure 3: Case 3 — (a) intraoral picture at first visit (b) two months after phase-1
therapy
280 Journal of Indian Society of Periodontology - Vol 14, Issue 4, Oct-Dec 2010
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Journal of Indian Society of Periodontology - Vol 14, Issue 4, Oct-Dec 2010 281