THE EFFECTS OF AMINOGLYCOSIDE

ADMINISTRATION ON POST-OPERATIVE
Non-Operative Management of Gastric
ORTHOPEDIC PATIENTS
Perforations
inIndra
Malang in 2016
Yudhika. Safrizal Rahman
Surgical Department dr.Sugiharto,
Darmadi, D.*, Zainoel Abidin
S.** Hospital/
*General SurgeryMedical Faculty
Resident of Syiah
of Brawijaya Kuala, Banda
University - SaifulAceh,
AnwarIndonesia
General Hospital Malang
** Digestive Surgery Department of Brawijaya University - Saiful Anwar General Hospital Malang

BACKGROUND METHOD
Incidence of surgical wound infection after This was a descriptive study conducted
orthopedic surgery was still high, i.e. 8-54%. at Zainoel Abidin General Hospital, Banda
Surgical wound infection could prolong Aceh, on July to September 2017. Samples
healing time and cause deformity to death. were determined using probability sampling
The use of aminoglycoside antibiotics method, which were the medical records of
after orthopedic surgery was common patients who had undergone orthopedic
practice to prevent infection of Gram- surgery on January to June 2017. Inclusion
negative aerobic and some anaerobic criteria were patients with grade III open
bacteria. fracture who underwent operation and had
aminoglycoside for five days. The incidence
of surgical wound infection was determined
OBJECTIVE by the level of white blood cells. The effect
To determine the effect of post-operation of aminoglycoside to the surgical wound
aminoglycoside administration to the infection was analyzed using univariate
incidence of surgical wound infection. analysis.

GENDER AGE

500 71.88% 458

250
200
240

400
150 137
300 337 94
128
100
200 83 105 118 98
236 50 1515 30 53
100 175 42
0
0 0 13 15 21
0
K
K
Aminoglycoside
Aminoglycoside <5yo 5-11yo 12-16yo 17-25yo 26-35yo
Male Female 36-45yo 46-55yo 56-65yo >65yo

LEUCOCYTE
PROCEDURE

300 265 600

500
200 183 207
400
509
145
100 58 75 69 300
75 69 200 271
0 42 286
6 12 100 140
K 0
Aminoglycoside
K
Short bone Long bone Aminoglycoside
Spine Debridement
< 10.500 > 10.500
Remobe Implant Joint replacement

RESULT The total subjects were 795 patients; most of them were male (57.6%).
The highest percentage of age group was 26-35 years old (30.2%). The most common
operation was operations of long bone fractures. Among the subjects, the proportion
of patients who had aminoglycoside and had white blood cell count <10.500 was
higher (65.9) than patients with white blood cell count >10.500.

CONCLUSION Aminoglycoside for 5 days after orthopedic surgery lead to

lower incidence of surgical wound infection.

Keywords : Wound infection, Aminoglycoside, Orthopedic surgery