Complications of Skin Phototherapy

Phototherapy is an essential option for adults in the treatment of certain skin diseases such as
psoriasis, a chronic, non-communicable disease known for its reddish, inflamed lesions with
silvery, or sometimes whitish, scales of dead skin. Phototherapy can also treat cases of atopic
dermatitis, a chronic, skin problem characterized by skin inflammation and itchiness, as well
as vitiligo, the loss of skin cells responsible for skin color, resulting in white patches on the
skin. While skin phototherapy is useful, it may cause complications.

Acute Sunburn
According to the DermNet NZ.org, an online publication of New Zealand Dermatological
Society, overexposure of the skin to the ultraviolet rays used in phototherapy can sometimes
cause acute sunburn. Anti-inflammatory medications, such as aspirin, can temporarily relieve
the pain and severity of acute sunburn. Other medications, such as topical steroids and
emollients, can also alleviate the pain.

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Ocular Toxicity
Ocular toxicity, or damage to the eyes, can be seen in patients undergoing phototherapy. This
can be in the form of photokeratitis, the UV-induced inflammation of the front part of the eye,
which can result in intense eye pain and in severe cases, impaired eye sight, as stated in
DermNet NZ.org. Use of artificial tears can temporarily ease the eye discomfort.

Polymorphous Light Eruption

Polymorphous light eruption is a kind of skin irritation that occurs on skin that is usually not
exposed to the sun, and can result from phototherapy. According to DermNet NZ.org,
treatment includes emollients and topical steroids, and reducing the UVB dose in increments.

Worsening of Skin Disease

Worsening of the actual skin disease being treated by phototherapy rarely occurs, but if it
does, phototherapy must be discontinued, according to DermNet NZ.org. Other treatment
options should to be considered.

Photo-aging
Photo-aging, which can include skin wrinkling, freckling, drying of the skin, and elastosis, or
lack of elasticity of the skin, may occur with long-term use of phototherapy.
Skin Cancer
Skin cancer, including solar keratoses, squamous cell carcinoma, basal cell carcinoma and
melanoma, can also be a long-term complication of phototherapy.

Bronze Baby Syndrome

Bronze baby syndrome can occur in infants with neonatal cholestatic jaundice when exposed
to UV rays used in phototherapy, according to an article published in February 2008 in the
"New England Journal of Medicine." This syndrome may manifest as brownish discoloration
of the skin and urine. However, when exposure to phototherapy is stopped and the cholestatic
jaundice resolves, the brownish discoloration also disappears.

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References

 DermNet NZ: UVB Phototherapy

 "Egyptian Dermatology Online Journal"; Controversial Results of Phototherapy in
The Treatment of Psoriasis; Amer, M et al.; May 2007
 "The New England Journal of Medicine"; Phototherapy in Neonatal Jaundice;
Maisels, M.J. et al.; February 2008

Article reviewed by Mia Paul Last updated on: Sep 14, 2010

Read more: http://www.livestrong.com/article/244279-complications-of-skin-

phototherapy/#ixzz1reyk9jCh

Sumber : http://www.livestrong.com/article/244279-complications-of-skin-phototherapy/
 Komplikasi Fototerapi Kulit
Sep 14, 2010 | Oleh Helen Nnama

Kredit foto gambar kulit oleh

Robert Kelly dari Fotolia.com

Fototerapi adalah pilihan penting untuk orang dewasa dalam pengobatan penyakit kulit
tertentu seperti psoriasis, kronis, penyakit tidak menular dikenal kemerahan, lesi meradang
dengan sisik keperakan, atau kadang-kadang keputihan, kulit mati. Fototerapi juga dapat
mengobati kasus dermatitis atopik, masalah, kulit kronis yang ditandai oleh peradangan kulit
dan gatal, serta vitiligo, hilangnya sel-sel kulit yang bertanggung jawab untuk warna kulit,
sehingga bercak putih pada kulit. Sementara fototerapi kulit berguna, dapat menyebabkan
komplikasi.

Akut Sunburn
Menurut NZ.org DermNet, sebuah publikasi online dari Masyarakat Selandia Baru
dermatologis, overexposure pada kulit terhadap sinar ultraviolet yang digunakan dalam
fototerapi kadang-kadang dapat menyebabkan kulit terbakar akut. Obat anti inflamasi, seperti
aspirin, untuk sementara dapat meredakan rasa sakit dan keparahan luka bakar akut. Obat
lain, seperti steroid topikal dan emolien, juga dapat mengurangi rasa sakit.

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Toksisitas pada mata

Toksisitas pada mata, atau kerusakan pada mata, dapat dilihat pada pasien yang menjalani
fototerapi. Ini bisa dalam bentuk photokeratitis, peradangan imbas UV dari bagian depan
mata, yang dapat mengakibatkan sakit mata intens dan pada kasus berat, gangguan
penglihatan mata, sebagaimana dinyatakan dalam NZ.org DermNet. Penggunaan air mata
buatan sementara dapat mengurangi ketidaknyamanan mata.
Polymorphous Cahaya Letusan
Letusan cahaya Polymorphous adalah semacam iritasi kulit yang terjadi pada kulit yang
biasanya tidak terkena matahari, dan dapat hasil dari fototerapi. Menurut DermNet NZ.org,
pengobatan termasuk emolien dan steroid topikal, dan mengurangi dosis UVB secara
bertahap.

Memburuknya Penyakit Kulit

Memburuknya penyakit kulit yang sebenarnya dirawat dengan fototerapi jarang terjadi, tetapi
jika tidak, fototerapi harus dihentikan, menurut DermNet NZ.org. Pilihan pengobatan lain
sebaiknya dipertimbangkan.

Foto-penuaan
Foto-penuaan, yang dapat mencakup kerutan kulit, freckling, mengeringkan kulit, dan
elastosis, atau kurangnya elastisitas kulit, mungkin terjadi dengan penggunaan jangka
panjang dari fototerapi.

Kanker Kulit
Kanker kulit, termasuk keratosis surya, karsinoma sel skuamosa, karsinoma sel basal dan
melanoma, juga dapat menjadi komplikasi jangka panjang dari fototerapi.

Perunggu Bayi Sindrom

Sindrom bayi Perunggu dapat terjadi pada bayi dengan ikterus kolestasis neonatal saat
terkena sinar UV yang digunakan dalam fototerapi, menurut sebuah artikel yang diterbitkan
pada Februari 2008 dalam "New England Journal of Medicine." Sindrom ini dapat
bermanifestasi sebagai perubahan warna kecoklatan pada kulit dan air seni. Namun, ketika
paparan fototerapi dihentikan dan kolestasis jaundice resolve, perubahan warna kecoklatan
juga menghilang.

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Referensi

 DermNet NZ: Fototerapi UVB

 "Journal Mesir Dermatology"; Hasil Kontroversial dari Fototerapi dalam The Pengobatan
Psoriasis; Amer, M dkk; Mei 2007.

 "The New England Journal of Medicine"; Fototerapi di Neonatal Jaundice; Maisels, MJ dkk;
Februari 2008.

Pasal terakhir oleh Mia Paulus terakhir diperbaharui pada tanggal: Sep 14, 2010

Read more: http://www.livestrong.com/article/244279-complications-of-skin-

phototherapy/#ixzz1rez8YI6q