Cardiovascular disease

Marfan syndrome Genetic disorder of the connective tissue.

Tall, thin, long arms, legs, fingers and toes.
Flexible joint, scoliosis
Serious complication includes mitral valve
prolapse/ aortic aneurysm

Xanthelasma Sharply demarcated yellowish deposit

Around eyelid
Increased risk of atherosclerosis.
Crackles Crackling noises made by lungs with
respiratory disease during inhalation.
Cracks at the base of lungs
‘popping open’ of small airways and alveoli
during exhalation.
Hepatomegaly Abnormal enlargement of liver
Pulsatile in tricuspid incompetence

Ascites Accumulation of fluid at peritoneal cavity

Abdominal cavity
Bruits Murmur
Splinter haemoorhoids Tiny blood clot under the nails.
Tendon xanthomas Irregular yellow patch or nodules on the skin
due to deposition of lipids.
Tendon appear to be yellow firm hypertropic
neoplasms.

Infective endocarditis is an infection of the

inner surface of the heart, usually the valves.
The clot (platelet & fibrin deposit) formed at
the damaged valves attracts bacteria forming
vegetations.
Due to the absence of blood supply to the
valves, vegetation is left intact
Septic Infected by bacteria.
Septic emboli Often: extrapulmonary location E.g.
intravenous site.
A lot – turn into lobar or bronchopneumonia
Combine with coagulant, break off, enter
circulatory system, clot.