Infectious Disease News | AUGUST 2014 | Healio.

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IN THE JOURNALS

11.5-28.5); perirectal screening increased
yield by 18.5% (95% CI, 7.4-33.2); and
throat cultures increased detection by
17.5% (95% CI, 12-24).
According to the researchers, the
findings underscore the importance of
identifying MRSA colonization in pa-
tients with HIV, particularly through ex-
tranasal screening.
“Given that HIV-infected individuals
are at increased risk for MRSA infection
and that colonization has been associated
with infection, these findings emphasize
the need for evaluation and implementa-
tion of MRSA prevention strategies that
for serotype 1, but not for serotype 3.
Shedding of serotypes 1 or 3 after 7
days of treatment was significantly cor-
related among both groups of children.
Researchers observed no significant
differences in shedding between children
who received no vaccine and shed vac-
cine poliovirus 7 days after the first dose
of bivalent OPV and those who did not
shed after the first dose.
Geometric mean titers for poliovirus-
specific neutralizing antibodies signifi-
cantly increased for both vaccines and
all serotypes 28 days after vaccination.
Geometric mean titers post-vaccination
were significantly greater after IPV than
bivalent OPV.
“The substantial benefit of using IPV
rather than further doses of OPV to
boost intestinal immunity in children
within the typical age range for mass vac-
cination supports its use as part of the
global eradication program,” study re-
searcher Nicholas C. Grassly, a professor
of infectious diseases at Imperial College
in London, said in a press release. n
Disclosure: The researchers report no relevant
financial disclosures.
– Written by Jen Byrne and Emily Shafer

we e p s t a k e s
NECTED
Y CON
STA

S
focus on this highly vulnerable popula-
tion,” the researchers wrote. “In this ef-
fort, specific attention should be drawn
to the important burden of colonization
in extranasal sites.” n
Disclosure: The researchers report no relevant
financial disclosures.

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