1 To protect the retina by absorbing the short-wave blue light and ultraviolet radiation and reducing oxidative stress. 2 Vitamin A is essential for many physiological processes, including maintaining the integrity and function of all surface tissues (epithelia) of the eye. 3 Vitamin A ensures the conjunctiva are able to produce mucous and provide a barrier to infection. Textbook of Medical Physiology Arthur C. Guyton, John E. Hall 11th edition 2006 Elsevier Inc
4 Vitamin A is present both in the cytoplasm of
the rods and in the pigment layer of the retina. Therefore, vitamin A is normally always available to form new retinal when needed. Conversely, when there is excess retinal in the retina. 5 Vitamin A is an important precursor of the photosensitive chemicals of the rods and cones. Human Physiology: From Cells to Systems, Seventh Edition Lauralee Sherwood 2010 Brooks/Cole, Cengage Learning
6 Adequate amounts of vitamin A must be
available for the synthesis of photopigments. 7 In ocular surface, vitamin A plays an important role in the maintenance of the cornea integrity. 8 Vitamin A vitamin A plays an important role in the formation of ocular lipofuscin Lipofuscin granules in the retinal pigment epithelium are lipid protein aggregates which are thought to represent the lifelong accumulation of the non-degradable end products from the phagocytosis of photoreceptor outer segments.