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MRI of The Peritoneum: Spectrum of Abnormalities
MRI of The Peritoneum: Spectrum of Abnormalities
A b d o m i n a l I m ag i n g • P i c t o r i a l E s s ay
MRI of the
Peritoneum
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A C E N T U
R Y O F
MRI Technique
Splenorenal Ligament MRI evaluation of the peritoneal cavity re-
Right Supramesocolic Space
quires meticulous attention to technique. Ap-
Left Supramesocolic Space propriate coil placement and homogeneous
Foramen of Winslow Lesser Sac fat suppression are essential. Oral contrast
material and IV glucagon, although not rou-
B tinely used, can improve image quality.
Pulse sequences used for MRI examination
Phrenocolic Ligament
of the peritoneum are similar to those of stan-
dard abdominal MRI. Our standard protocol
comprises four types of sequences: a coronal
Small-Bowel Mesentery
Transverse
T2-weighted single-shot fast spin-echo or
Mesocolon HASTE sequence; a turbo or fast spin-echo
T2-weighted or long-TE inversion-recovery
breath-hold sequence in the axial plane (STIR
Ascending Colon eliminates field artifacts and is usually
Descending Colon performed as a fat-saturated T2-weighted
pulse sequence); a gradient-recalled-echo T1-
Right Inframesocolic Space
weighted chemical-shift in-phase and out-of-
Left Inframesocolic Space phase breath-hold sequence in the axial plane;
Dependent Pelvis and a 3D gradient-echo breath-hold sequence,
such as a volumetric interpolated breath-hold
C
examination, which is fat suppressed.
Dynamic gadolinium-enhanced images
must be included, because peritoneal disease
This space can be affected by abnormalities bound medially by the falciform ligament, typically enhances slowly after contrast ad-
involving the left hepatic lobe, lesser gastric and a posterior component, known as the ministration [3]. The arterial phase images are
curvature, anterior gastric and duodenal lesser sac. The two right supramesocolic acquired at 15–20 sec, the portal phase im-
walls, and anterior wall of the gallbladder. spaces communicate via the foramen of Win- ages at 60–90 sec, and the delayed phase
The right supramesocolic peritoneal space slow. Morison’s pouch (also known as the images at 5 min after IV contrast injection.
comprises an anterior perihepatic region, hepatorenal fossa) is a recess between the Homogeneous fat suppression is a critical
bowel loops and fat abdominal wall, usually as the result of a con-
herniating through right genital defect, a loss of tissue strength, or
external inguinal ring. trauma. Hernias are typically described by an-
atomic location. MRI characterizes hernias
well on the basis of its ability to differentiate
tissue planes.
Spigelian Hernia
A spigelian hernia is a hernia through the
lateral ventral abdominal wall at the point
where the semilunar and semicircular lines
intersect at the lateral border of the rectus ab-
dominus, also known as the spigelian apo-
neurosis. Classic spigelian hernias are cranial
to the junction of the inferior epigastric ves-
sels and the spigelian aponeurosis. Visualiza-
tion of a spigelian hernia on physical exami-
nation can be difficult, particularly in obese
patients. Bowel may herniate through the
spigelian hernia and become incarcerated or
strangulated. Omentum may also herniate
B through the spigelian aponeurosis. Abdomi-
nal pain may result from omental infarction
within a spigelian hernia.
Incisional Hernia
An incisional hernia results during or af-
ter closure of anterior abdominal wall inci-
sions (Fig. 3). Imaging may be useful for
showing the size and location of the abdom-
inal defect, particularly in obese patients,
and for differentiating hernia from he-
matoma early after surgery. MRI provides
excellent multiplanar tissue resolution for
hernia characterization [4].
Fig. 3—51-year-old
woman with left ventral
Peritoneal Inflammation and
incisional hernia. Axial
T1-weighted 3D Intraperitoneal Fluid
volumetric interpolated Inflammatory peritoneal disease may re-
breath-hold image sult in acute or chronic peritonitis. Peritonitis
shows left incisional
hernia containing may be infectious and is typically seen in the
mesenteric fat and small- setting of bowel perforation, diverticulitis,
bowel loops (arrow). appendicitis, or severe cholecystitis. Bacterial
peritonitis may also result from peritoneal in- Noninfectious causes of peritonitis include A dynamic, enhanced gradient-echo pulse
strumentation, such as peritoneal dialysis, pancreatitis and systemic diseases such as sequence is particularly pertinent for the diag-
surgery, or penetrating abdominal trauma. systemic lupus erythematosus. nosis of peritonitis. The administration of IV
contrast material produces peritoneal en-
hancement in cases of peritonitis. The perito-
neal contour may remain smooth, in contrast
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cused-echo sequences are the most sensitive Intraperitoneal Bile Leak dium (Teslascan, GE Healthcare), which results
in depicting dephasing artifacts from free A bile leak usually results from surgery and is in increased intraperitoneal T1 signal intensity
air due to “blooming” associated with mag- clinically occult when the leakage is present in on delayed enhanced images (Fig. 9). This in-
netic field inhomogeneities at air–tissue in- small amounts. An active bile leak can be eluci- creased signal results from biliary excretion of
terfaces [7] (Fig. 8). dated by administration of mangafodipir triso- the contrast agent, which usually collects in the
right upper quadrant. Formation of a pseudocap-
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Peritoneal Neoplasms
Benign Tumors
A variety of benign tumors of the perito-
A neum can manifest as soft-tissue masses.
These lesions include lipomas, neurofibromas,
and other mesenchymal tumors. Peritoneal and
mesenteric neurofibromatosis is uncommon,
seen most often in patients with a diagnosis of
neurofibromatosis type 1 (von Reckling-
hausen’s disease). Peritoneal and mesenteric
neurofibromas have MRI characteristics simi-
lar to those of neurofibromas in other anatomic
locations. Typically, neurofibromas are hypo-
to isointense to muscle on T1-weighted im-
ages, are hyperintense to muscle on T2-
weighted images, and show moderate to brisk
gadolinium enhancement [9] (Fig. 11). Both
T2-weighted and gadolinium-enhanced T1-
weighted gradient-echo pulse sequences are
useful for the diagnosis of neurofibromatosis.
Cystic mesothelioma of the peritoneum is a
rare benign neoplasm that occurs predomi-
nantly in women and tends to recur locally. It
is seen as a multilocular mass that can be con-
fused with other intraperitoneal cystic lesions.
Malignant Tumors
Peritoneal mesothelioma—Primary peri-
B toneal mesothelioma is a rare neoplastic
B C
A B
Fig. 8—54-year-old man with pneumoperitoneum.
A and B, Axial in-phase (A) and out-of-phase (B) images show small amount of free air (arrows). Conspicuity is increased on in-phase images because of longer TE, resulting
in greater susceptibility artifact.
and can be divided into lymphatic, mesothe- and hemorrhagic cysts have an intermediate ectopic endometrium is responsive to ovarian
lial, enteric, or urogenital types or may be to high T1 signal. Mesenteric cysts show no hormones, resulting in a typical cyclic pat-
related to prior infection or trauma. The typ- internal enhancement with gadolinium che- tern of symptoms. Endometrial implants
ical MRI appearance of mesenteric cysts is lates (Fig. 16). commonly involve the serosal surface of the
A B
Fig. 10—52-year-old man with biloma.
A and B, Axial T1-weighted 3D gradient-refocused-echo volumetric interpolated breath-hold image (A) and axial T2-weighted inversion recovery image (B) show lambda-
shaped fluid collection (arrows) adjacent to caudate lobe, representing biloma.
A B
Fig. 12—58-year-old man with mesothelioma.
A–C, Gradient-refocused-echo out-of-phase image (A) and enhanced axial T1-
weighted 3D gradient-refocused-echo volumetric interpolated breath-hold images
(B and C) show enhancing large mass (arrows, A and B), representing mesothelioma,
which is entangling bowel loops.
Fig. 13—44-year-old woman with metastases from ovarian cancer. Axial enhanced Fig. 14—41-year-old woman with ovarian cancer. Axial fat-suppressed gradient-
T1-weighted 3D gradient-refocused-echo volumetric interpolated breath-hold image refocused-echo T1-weighted enhanced image shows peritoneal tumor implants in
shows nodular enhancement of peritoneum over liver surface (arrows), representing perihepatic space (white arrow) and Morison’s pouch (black arrow).
metastases in patient with history of ovarian cancer.
A B
Fig. 15—48-year-old woman with mesenteric
carcinoid tumor.
A, Three-dimensional subvolume maximum-intensity
projection shows narrowing of ileocolic artery (arrow).
B and C, Enhancing mass (arrows) is seen on portal
venous phase images, with involvement of draining veins.
ovary, where they can be cystic and are re- decreased T2 signal). Chronic hemorrhage or teratomas. Common locations for endome-
ferred to as endometriomas or chocolate fibrosis can result in focal areas of signal trial implants, in addition to the ovaries, in-
cysts. The implants can incite an inflamma- void on both T1- and T2-weighted images clude the peritoneal lining around the rec-
tory reaction resulting in adhesions and fi- [17]. Fat-suppressed T1-weighted imaging is tovaginal pouch and the abdominal wall [16].
brosis. Because of cyclic hormonal stimula- the most sensitive MRI technique for depict-
tion, endometriomas often exhibit varying ing endometriomas [18]. The use of fat satu- Conclusion
stages of hemorrhage (most commonly in- ration helps to distinguish endometrial im- The peritoneum, including peritoneal re-
creased T1 and T2 signal or increased T1 and plants from fatty lesions, such as ovarian flections and spaces, is difficult to visualize
A B
Fig. 16—51-year-old man with mesenteric cyst.
A, Axial enhanced T1-weighted 3D gradient-refocused-echo volumetric interpolated breath-hold image shows large, nonenhancing extrahepatic cystic structure (arrow)
posterior to portal vein and anterior to hepatic artery, representing mesenteric cyst.
B, T2-weighted image shows homogeneously bright signal (arrow).
Fig. 17—48-year-old woman with cystic liver lesion incidentally discovered on CT.
A, Coronal T2-weighted HASTE image shows high-signal-intensity lesion (arrow)
posterior to right hepatic lobe.
B and C, Unsubtracted (B) and subtracted (C) axial T1-weighted gadolinium-
enhanced images show capsule-based lesion (arrows) secondary to endometriosis.
B C
when it is healthy. However, knowledge of 4. Wechsler RJ, Kurtz AB, Needleman L, et al. Cross- lation. J Magn Reson Imaging 1993; 3:99–106
these peritoneal reflections improves our in- sectional imaging of abdominal wall hernias. AJR 12. Low RN, Semelka RC, Worawattanakul S, et al. Ex-
terpretation of imaging studies of patients 1989; 153:517–521 trahepatic abdominal imaging in patients with ma-
with peritoneal disease, including hernias, 5. Kanematsu M, Hoshi H, Murakami T, et al. Spon- lignancy: comparison of MR imaging and helical
peritonitis, and neoplasia. taneous bacterial peritonitis in cirrhosis: enhance- CT with subsequent surgical correlation. Radiology
Successful MRI of the peritoneum de- ment of ascites on delayed MR imaging Radiat Med 1999; 210:625–632
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pends critically on imaging technique. Ho- 1997; 15:185–187 13. Chou CK, Liu GC, Su JH, et al. MRI demonstration
mogeneous fat suppression and dynamic 6. Warshauer DM, Lee JK. Imaging manifestations of of peritoneal implants. Abdom Imaging 1994;
contrast-enhanced imaging, including de- abdominal sarcoidosis. AJR 2004; 182:15–28 19:95–101
layed imaging, are important technical fac- 7. Rabushka LS, Kuhlman JE. Pneumatosis intestina- 14. Bader TR, Semelka RC, Chiu VC, et al. MRI of car-
tors for successful detection and character- lis: appearance on MR examination. Clin Imaging cinoid tumors: spectrum of appearances in the gas-
ization of lesions. 1994; 18:258–261 trointestinal tract and liver. J Magn Reson Imaging
8. Shigemura T, Yamamoto F, Shilpaker SK. MRI dif- 2001; 14:261–269
ferential diagnosis of intrahepatic biloma from sub- 15. Ros PR, Olmsted WW, Moser RP Jr, et al. Me-
References acute hematoma Abdom Imaging 1995; 20:211–213 senteric and omental cysts: histologic classifica-
1. Healy JC, Reznek RH. The peritoneum, mesenter- 9. Fenton LZ, Foreman N, Wyatt-Ashmead J. Diffuse, tion with imaging correlation. Radiology 1987;
ies and omenta: normal anatomy and pathological retroperitoneal mesenteric and intrahepatic peripor- 164:327–332
processes. Eur Radiol 1998; 8:886–900 tal plexiform neurofibroma in a 5-year-old boy. Pe- 16. Olive DL, Schwartz LB. Endometriosis. N Engl J
2. Meyers MA, Oliphant M, Berne AS, et al. The peri- diatr Radiol. 2001; 31:637–639 Med 1993; 17:328:1759–1769
toneal ligaments and mesenteries: pathways of in- 10. Loggie BW. Malignant peritoneal mesothelioma. 17. Siegelman ES, Outwater E, Wang T, et al. Solid pel-
traabdominal spread of disease. Radiology 1987; Curr Treat Options Oncol 2001; 2:395–399 vic masses caused by endometriosis: MR imaging
163:593–604 11. Semelka RC, Lawrence PH, Shoenut P, et al. Pri- features. AJR 1994; 163:357–361
3. Low RN. Gadolinium-enhanced MR imaging of mary ovarian cancer: prospective comparison of 18. Sugimura K, Okizuka H, Imaoka I, et al. Pelvic en-
liver capsule and peritoneum. Magn Reson Imaging contrast-enhanced CT and pre- and postcontrast, dometriosis: detection and diagnosis with chemical
Clin N Am 2001; 9:803–819 fat-suppressed MR imaging, with histologic corre- shift MR imaging. Radiology 1993; 188:435–438