DRUG, MECHANISM INDICATIONS CONTRA- SIDE EFFECTS ADVERSE REACTIONS DRUG NURSING REMARKS

DOSAGE OF ACTION INDICATIONS INTERACTIONS RESPONSIBILITIES

& ROUTE
Lactulose The drug Treatment of Contraindicated Abdominal GI DRUG-DRUG History
30 cc syrup passes constipation. with allergy to fullness, Transient flatulence, Do not Allergy to lactulose,
OD HS unchanged into lactulose, low- flatulence, distention, intestinal administer low-galactose diet.
8pm the colon Prevention and galactose diet. belching. cramps, belching, diarrhea, other laxatives diabetes, pregnancy,
where bacteria treatment of nausea. with lactulose. and lactation.
Laxative, break it down portal-systemic Use cautiously with
Ammonia to organic acids encephalopathy. diabetes, Other DRUG-FOOD Physical
reduction that increase pregnancy, and Acid-base imbalances May be taken Abdominal
drug the osmotic lactation. with fruit juice examination, bowel
pressure in the or milk to sounds, serum
colon and increase electrolytes, serum
slightly acidify palatability. ammonia levels.
the colonic
contents, Do not freeze
resulting in an laxative form. Ask
increase in patient to report
stool water diarrhea, severe
content, stool belching, abdominal
softening, fullness.
laxative action.
This also
results in
migration of
blood
ammonia into
the colon
contents with
subsequent
trapping and
expulsion of
feces.