DRUG STUDY FORM

Drug Name Classification Mechanism of Action Side Effects/ Nursing Responsibilities/

Adverse Effects Patient and Family Health Teachings
PHARMACOTHERAP Blocks vasoconstrictor, SE: Frequent (8%): Upper 1. Assess blood pressure periodically and compare
Generic Name EUTIC: Angiotensin II aldosterone-secreting effects respiratory tract infection. it to normal values. R: to help document
receptor antagonist of angiotensin II, inhibiting Occasional (4%–2%): Dizziness, antihypertensive effects
losartan binding of angiotensin II to AT1 diarrhea, cough. Rare (1% or less): 2. Assess for the mentioned contraindications to this
CLINICAL: receptors. Therapeutic Effect: Insomnia, dyspepsia, heartburn, drug (e.g. renal impairment, hyponatremia,
Brand Name Antihypertensive Causes back/leg pain, muscle cramps, hypovolemia, etc.). R: to prevent potential
vasodilation, decreases myalgia, nasal congestion, adverse effects
peripheral resistance, sinusitis, depression. 3. Obtain baseline status for weight, vital signs,
Cozaar
decreases B/P. overall skin condition, and laboratory tests like
AE: Overdosage may manifest as renal and hepatic function tests, serum electrolyte,
hypotension and tachycardia. and complete blood count (CBC) with differential.
Bradycardia occurs less often. R: to assess patient’s response to therapy
Institute supportive measures. 4. Administer drug on empty stomach one hour
before or two hours after meal. R: to ensure
optimum drug absorption.
5. Monitor renal and hepatic function tests R: to
alert doctor for possible development of renal
and/or hepatic failure as well as to signal need
for reduced drug dose
6. Monitor blood pressure and heart rate and rhythm.
R: to detect possible development of adverse
effects.
7. Monitor for presence of manifestations that signal
decreased in fluid volume (e.g. diarrhea, vomiting,
dehydration). R: to prevent exacerbation of
hypotensive effects of drugs.
Picture Indication Pharmacokinetics Pharmacodynamics
 Hypertension, Well absorbed after PO PO 8. Educate patients on the importance of healthy
Nephepatically in administration. Protein Onset: N/A lifestyle choices which include regular exercise,
type 2 diabetes binding: 98%. Peak: 6hrs weight loss, smoking cessation, and low-sodium
person, to reduce Metabolized in the liver. Duration: 24hrs diet. R: to maximize the effect of
risk of CVA in Excreted in urine (35%), antihypertensive therapy.
9. Educate patients and family members about the
patients with feces (60%). Not
drug's effect on the body and manifestations that
hypertension and removed by would need reporting. R: to enhance patient
left ventricular hemodialysis. Half- life: knowledge on drug therapy and promote
hypertrophy 2 hrs; metabolite, 6–9 adherence.
hrs. 10. Emphasize to the client the importance of
strict adherence to drug therapy. R: to ensure
maximum therapeutic effects.

Reference:
- Hodgson, B. B., & Kizior, R. J. (2019). Saunders nursing drug handbook.