Aripiprazole is a partial agonist at D2 receptors that can act as an antipsychotic by lowering dopaminergic neurotransmission in the mesolimbic pathway and enhancing dopaminergic activity in the mesocortical pathway. It is indicated for the management of severely ill schizophrenics who are unresponsive to standard antipsychotic drugs and for reducing the risk of recurrent suicidal behavior in patients with schizophrenia. Common adverse effects include cerebrovascular events, suicidal thoughts, weight gain, postural hypotension, and extrapyramidal symptoms. Nursing responsibilities involve inspecting injections for particulate matter or discoloration, encouraging voiding after administration, monitoring for signs of infection or neuroleptic malignant syndrome, and checking for
Aripiprazole is a partial agonist at D2 receptors that can act as an antipsychotic by lowering dopaminergic neurotransmission in the mesolimbic pathway and enhancing dopaminergic activity in the mesocortical pathway. It is indicated for the management of severely ill schizophrenics who are unresponsive to standard antipsychotic drugs and for reducing the risk of recurrent suicidal behavior in patients with schizophrenia. Common adverse effects include cerebrovascular events, suicidal thoughts, weight gain, postural hypotension, and extrapyramidal symptoms. Nursing responsibilities involve inspecting injections for particulate matter or discoloration, encouraging voiding after administration, monitoring for signs of infection or neuroleptic malignant syndrome, and checking for
Aripiprazole is a partial agonist at D2 receptors that can act as an antipsychotic by lowering dopaminergic neurotransmission in the mesolimbic pathway and enhancing dopaminergic activity in the mesocortical pathway. It is indicated for the management of severely ill schizophrenics who are unresponsive to standard antipsychotic drugs and for reducing the risk of recurrent suicidal behavior in patients with schizophrenia. Common adverse effects include cerebrovascular events, suicidal thoughts, weight gain, postural hypotension, and extrapyramidal symptoms. Nursing responsibilities involve inspecting injections for particulate matter or discoloration, encouraging voiding after administration, monitoring for signs of infection or neuroleptic malignant syndrome, and checking for
DRUG NAME MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING
ACTION RESPONSIBILITIES
Aripiprazole is a Management Contraindicated with >Cerebrovascular >Inspect I.M.
Generic Name: partial agonist at of severely ill allergy to olanzapine, including stroke solution for Aripiprazole D2 receptors. It schizophrenics myeloproliferative >Suicidal thoughts particulate matter may act as an who are disorders, severe CNS and behaviors in and discoloration Brand Name: antipsychotic by: unresponsive depression, children before Abilify >Lowering to standard comatose states and >Weight gain administration. dopaminergic antipsychotic lactation. >Postural > Encourage neurotransmission Dosage: drugs. hypotension patient to void in the mesolimbic 10-15mg P.O Reduction of >Extrapyramidal after taking the pathway. 400mg I.M. >Enhancing the risk of symptoms drug to help dopaminergic recurrent >Lightheadedness decrease activity in the suicidal >Drowsiness anticholinergic mesocortical behavior in >Hyperglycemia effects of urinary Route: pathway. patients with >Increased risk of retention. - Oral schizophrenia hyperlipidemia > Monitor for - I.M (not orally >Neuroleptic elevations of disintegrating Malignant temperature and Therapeutic tablet). Syndrome differentiate Classification: >Tardive between infection Atypical dyskinesia and neuroleptic antipsychotic > Leukopenia malignant drug > Neutropenia syndrome. >Seizures >Monitor for >Convulsion orthostatic Pharmacologic >Suicide hypotension and Classification: >Dysphagia provide Second appropriate Generation safety measures antipsychotic as needed. > Monitor patient regularly for signs and symptoms of diabetes mellitus; monitor lipid and triglyceride levels. > Peel back foil on blister pack of disintegrating tablets; do not push through foil; use dry hands to remove tablet, place entire tablet in mouth.