* 1 ROEN ‘Trang 1/10 clothymicin ON TAP HOA DUGC 1 oe idovudin (AZT) la thudc o6 téc dong: A.Ue ché reverse transcriptase c6 edu tréic nucleosid theo co ché tre ché khéng tang tranh. MEF Uic ché reverse transcriptase c6 c4u tric nucleosid theo co ché tre ché tong tranh. — . Ue ché reverse transcriptase khong cé cdu tric nucleosid theo co ché tic déng lén diém allosteric. D. Ue ché reverse transcriptase khOng c6 cu tric nucleosid theo co ché ttc ché trong tranh. Th tehrctrg Rats >, TH nda VRS Gee Cay 2: Hop chét (3) 1a khang sinh Cephalosporin: ‘dc dung manh trén Gram 4m, uéng dugc, bén véi B-lactamase — B. Tac dung trén vi khudn Gram am, ung duge C. Kém bén vi B-lactamase, uéng duge D. Tée dung manh trén vi khudin Gram am, ding curdmg tiém, ben véi B-lactamase. dah. t / (QO EDI fh Lactima % Goo! @) 2 (Cu 3: Gidi han quan trong khi khuttinh khiét BaSO¢: I. Gidi han acid-base; IT. Hyp chat sulfur khdng thé oxi héa; 111, Mui héa tan; TV, Su lang AILM. BLT I a Cu 4: Nhdm chitc Lién quan dén tinh kém bén ving cia khéng sinh thuge ho Macrolid trong maj tring kiém 46 I 4. Nh dlmethylamino trong phn t dng amino . B. Nhém C=O (C10) trong phin genin ctia Macrolid -> © bir hong aud eh OH trong phan tir duong desoxyribose ‘Nhém Ester n9i trong phan genin etia Macrolid E iu 5: Hudng nghién otru bién ddi cdu tric: Tao edu tric @4nh lira protein van chuyén, gidp van chuyén nhanh chéng vao muc tiéu tic QGng: “SSS: wiSince gh dite. A. Uracil +5-Fluorouracil B, Acid folic -Methotrexat C. Cytosin >Cytarabin en rin -*6-Mercaptopurin -~ Cau 6: Co ché téc dong chung cita cdc din chit 5-nitroimidazol trén cdc dom bao (protozoa) A. Téc dng trén kénh Na‘ trén mang té bao lim ting lng Na+ ndi bao, B. Phong bé qué trinh ting hgp protein eda té bao protozoa C,Z.am thay ddi tinh thim mang té bao ifn gay chuéi ADN ella ede protozoa ~ ‘au 7: Thudc tri giun san nhém benzimidazol cé nhiing dic diém sau: - A. M6t 86 thude dién hinh trong nhém nite: pyrantel, morantel, praziquantel... 0" -febaaiycboopipinide B. Trong edu tric o6 khung 5-nitroimidazol 7 3 'éc d6ng t6t trén giun tron va mét s6 loai sdn, 1a nhém thuéc chi yéu duge ding hign may. D. Hau hét la cht long, dang dau tan t6t trong nude, ding dang thude tiém. Cu 8: D6 kiém cia nuréc Javel do chit no gay ra: I. NaOH; I. NaHCOs; IIl. Na,CO3 AE, BLU C., HI 1, UL I ‘Cfiu 9: Hung nghién ott bién déi cdu tric: Cu trac trong ty nhung c6 tic @ng abi kbang ‘. Uracil 5-Ethylnyluracil ~ B. 5-Fluorouracil -Floxuridin. ties ctstée C. Terfenadin +Fexofenadin D. Zaprinast ~Sildernafil HuFu‘Trang 2/10 C&u 10: Khi ding INH, cin cha y: A,Nén ding chung INH va B6 B. nén ding B6 truvie INH ‘Kh6ng nén ding chung INH vaB6~ —_D. Nén ding B6 sau INH C&u 11: Phéc dé chinh sir dung trong diéu tri viém gan siéu vi C la diéu tri phdi hop "EG-Interferron + Ribavirin” B.Interferron + Entercavir C. Interferron + Ribavirin D. PEG - Interferron + Entercarvir ‘Cau 12: Thanh phin cia mét duge phim phéng xe: I. Chat mang, II. Chat din, TIT. Ci tac, IV. Chat dinh huéng, V. Chét dénh dau. ae Ve BLILV CLIN D.IV,V “au 13: Lién quan edu tric va tac dung ciia khang sinh ho Tetracycline, cc phat biéu sau 3b hes day la dang, ngo¢ Kh Pet \ ehh OH phan cyc manh: Thuéc dé tan, hap thu tét qua rudt va mang té bao VK. — B. Su-cé mit cla nhém OH & C6 Lim phn tir kém bén trong méi tru’mg acid C. Nhém amin can thiét dé tgo lign két gitta thuéc va receptor — D. Nhém OH va keto tgo phic véi ion kim logi, giam hap thu thuée khi dling trong bita an 14: Huéng nghién citu bién ddi cdu tric: sir dung chdt chuyén héa cé tac dung: Proguanil +Cycloguanil Af ¢&) —_ B.Lansoprazol -Dexlansoprazol C. Morphin “Fentanyl D. Dapson ~*Acedapson 15: Co ché téc dung cia Rifampicin: ( vcerng Cup) ‘Gan trén ARN polymerase tre ché tong hop ARN Vi khuan — iin trén katalase tre ché tong hyp ARN vi khudn C. gin trén peroxidase irc ché tong hop ADN vi khudn Gin trén ADN Gyrase ite ché tn; ‘i kha ‘CAu,16: Clindamycin sir dung 6 ligu thap hon so véi Lincomycin 1a do cdc yéu t6 nao sau 2 aay) Hap thu qua rugt t6t hon; I. ft gay ddc voi hé vi sinh vt dung rugt khi ding dur ~ udng, IIL. Chat chuyén héa qua gan cia Clindamycin van con tic dung khang kht ve: BI cl D. I valll Cu 17: Hyp chit (4) li Khing sinh Cephalosperin: A. Kém bén véi B-lactamase, ding duimg tiém. B. Tac dung manh trén VK Gram (-) lin Gram (+), uéng duge + G, Tae dung manh trén VK Gram (-) va Gram (+), ung duge, ben véi B-lactamase. Ke dung manh trén VK Gram (-) ((b),ben, vai lactamase, diing duémg tiém,<— =, Whssif B-Ractounene axGng dee COCR ester ee ant ag phe 6 fea aC) (> ti ay fg hyp cu tric twong ty voi muc dich Paclitaxel -* Doxetacel (-f ) B. Guanin Acyclovir forphin ~*Feta D. omeprazol -Esomeprazol Cau 19: Trong sé cdc khang sinh (5), (6), (8) cht nao cé thé sir dung bing dung uéng, Se {CoH afer ee oc Oe Praha Ware) gy Peni cin G “beni han HuFuTrang 3/10 Digm A. (5) va (8) B.(6)va(8) C.(8) Ge a Céiu 20: Lién quan céu triic va téc dung khéng khudn cia cae khing sinh cyclin: nhém Kh6ng can thiét d6i voi téc dung khéng khudn cé thé logi bé khdi cdu tric A. Nhdm N(CHs)2 6 vi tri Cy, B. Nhégn GH; (a) 6 vi tei C C_Nh6m OH (B) & vi tei Ce Ci 2 nhém CH, va OW & vj tri Ce-— C4 24: don vi cla "Clo hogt tinh" duge biéu thi bang gl“ —-B.mgiml —C. gikg D. mi/I ‘Cau 22: Khang sinh ho Macrolid thuéng duoc san xudt dudi dang muéi, ester hoe mudi ester dé cai thién 46 béii vimmg, Blam ding, ting tinh tan.... Cho biet thudc nao sau day c6 49 tan tt nhat o6 thé pha tiém (trong dung lg 1a nude eft): al < yer AD: « 408, Jo ‘Es ‘A. Erythromycin stearat — Erythromycin succin: C. Erythromycin propionat/|\, \D. Erythromycin palmitat'\\ jy: Cfu 23: Hop chat (7) 1a: L a aucainet 24sec att Q \ Jv - otelet, HH, - \, pdectcon caretecl, catheter Ro. Sulbactam is Sateel el CCH Tazohactam HCOOH (7) ‘A. Chit tte ché cephalosporinase B, Khang sinh ho f-lactam C. Chit ire ché dehydropeptidase \Q Chit ite ché penicillinase ~ C4u 24: Enzyme nao tham gia vjp téc dung ciia INH: A. Glutathion reductase WW Feronydase C. Cytocrom P-450 D.ADN gyrase iceefextoue (Céu 25: Diéu kign 4é thu duge Bari sulfat o6 46 min cao: I. Nhiét 6 thdp, II. Nhiét 48 cao, III. Dung dich long, IV. Dung dich dim dc, V. NaySO, du, VI. BaCl; du ALIV, VI B.ILIV,V cmv NI, Ve CAu 26: Céc quinolon tic déng én qué trin! . A, Gin 2 chudi ADN B. Téch 2 chudi ADN C. Xofin cia ADN Dubi thing ctia ADN, E ‘Cau 27: Hop chat (1) ld khang sinh B-lactam c6 edu tri o™ COOH L A.Penam —_B. Cephem Nye teceptei @. carvapenem ‘Cfiu 28: Clofazimin téc dng trén: A, Topoisomerase __ B.ADN gyrase ik “Guanin - Cytosin trén chudi kép D. Thymin - adenin trén chudi kép oe Vai trd cia during amino trong cu trite khdng sinh ho Macrolid: Lam tuong téc gitta thude va thy thé manh hon Vira ting tinh thin di, vira ting tong téc thude va thy thé A~ C. Lam ting tinh thin dua cia phan 1B D. chéng su khang thuéc cita vi khudn CAu 30: Cac phat biéu sau day 14 ding véi vancomycin ngoai tit A. Dc tinh: c6 dc tinh trén thin» B.Duge dong hoc: Gan nhu khéng hip thu qua hé tiéu hoa_~ Phé khang khudn: Dac biét gram am 4é khang D. Cau tgo: La mét glycopeptid ~ thude, cdi thign duge dong hoc cia thube HuFu