PHARMACOLOGY

1. Calcium channel blocking agent used in treatment of hypertension.

a) AmlodIpine
b) Propranolol
c) Glyceryl trinitrite
d) Furosimide
2. Adverse effect of nifedipine.
a) Headache
b) Flushing
c) Ankle swelling
d) All of above
3. Which of the Calcium channel blocking agent show greater effect on smooth muscle.
a) Verapamil
b) Diltiazem
c) Nefidepine
d) All of above
4. Following Calcium channel blocking drug increase reflex tachycardia.
a) Verapamil
b) Nifedipine
c) Diltiazem
d) All of above
5. Repeated administration of nitrates leads to diminished relaxation because.
a) Increase in SH groups
b) depletion in SH groups
c) no change in SH groups
d) none of the above
6. Adverse effect of verapamil.
a) Constipation
b) Vomiting
c) Nausea
d) diarrhoea
7. antianginal action of nitrates.
a) Reduction of cardiac oxygen consumption by reducing preload & afterload
b) Coronary flow towards ischemic area via collaterals
c) Relief of coronary spasm
d) All of above
8. Action of beta blockers used in treatment of angina pectoris.
a) Slows the heartrate and reduce the metabolic oxygen demand
b) Increase heartrate and reduce oxygen demand
c) Both a & b
d) None
9. Following drug produce improved perfusion,reduce oxygen demand to heart.
a) Glyceryl trinitrate
b) Verapamil
c) A&b
d) None
10. Phenyl alkylamine calcium channel blocker.
a) Verapamil
b) Nifedipine
c) Diltiazem
d) none
11. potassium channel activater
a) nifedipine
b) nicorandil
c) nebivolol
d) all of above
12. Angina characterised by pain at rest
a) Stable Angina

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b) unStable Angina
c) variant Angina
d) none
13. phosphoiesterase inhibitor used in CHF
a) Amrinone
b) Milrinone
c) A&b
d) Dobutamine
14. Increase in potassium ion concentration
a) Decrease effect of cardiac glycosides
b) increase effect of cardiac glycosides
c) no effect of cardiac glycosides
d) none
15. Hormone used in treatment of CHF
a) Insulin
b) Glucagon
c) Stomatostatin
d) All of above
16. Diuretic as aldosterone antagonist
a) Furosemide
b) Sironolactone
c) Dichlorothiazide
d) Captopril
17. Vasodilator which releases NO
a) Nifedipine
b) Hydralazine
c) Minoxidil
d) Sodium nitroprusside
18. Hydralazine can produce
a) Seizures
b) Tachycardia
c) Hepatitis
d) Aplastic anaemia
19. Endogenous vasoconstrictor stimulates aldosterone release from glands
a) Angiotensinogen
b) Angiotensin-I
c) Angiotensin-II
d) ACE
20. Use of beta blockers for hypertensive treatment is
a) Peripheral vasodilation
b) Diminishing blood volume
c) Decrease of heart work
d) Depression of vasomotor centre

21. Unwanted effect of clonidine

a) Parkinsons syndrome
b) Sedative & hypnotic syndrome
c) Agranulocytosis & Aplastic anemia
d) Dry cough & respiratory depression
22. Actions of verapamil except
a) Blocks T type calcium channel
b) Increases heart rate
c) Relaxes coronary artery smooth muscle
d) Depresses cardiac contractility
23. All regarding vasodilators are true except

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a) Hydralazine causes tachycardia

b) Nifedipine is a dopamine receptor antagonist
c) Nitroprusside dilates both arterioles
d) Minoxidil can cause hypertrichosis
24. Which of the following drug produces tachycardia
a) Propranolol
b) Clonidine
c) Enalapril
d) Nifedipine
25. Which of the following drug converted to active metabolite after absorption
a) Labetalol
b) Clonidine
c) Enlapril
d) Nifedipine
26. Drug contracted in patients with bronchial asthma
a) Propranolol
b) Clonidine
c) Enlapril
d) nifedipine
27. nonpeptide angiotensin II receptor antagonist
a) clonidine
b) captopril
c) losartan
d) diazoxide
28. antihypertensive drug activates alfa2 adrenergic receptors
a) labetolol
b) phentolamine
c) clonidine
d) enlapril
29. antihypertensive drug activates alfa1 adrenergic receptors
a) prazocin
b) clonidine
c) enlapril
d) nifedipine
30. diuretic for treatment of hypertension
a) losartan
b) dichlorthiazide
c) captopril
d) prazocin
31. directly acting vasodilator
a) labetalol
b) clonidine
c) enlapril
d) nifedipine