GENERIC NAME :cefixime

BRAND NAME: gracefix

INDICATION: Treatment of infections due to sensitive gm +ve & gm -ve bacteria.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Hypersensitivity reactions including skin rashes, urticaria, eosinophilia,
fever, serum sickness-like reactions & anaphylaxis. GI disturbances especially diarrhea.

GENERIC NAME: cefuroxime na

BRAND NAME: groxime
INDICATION: Treatment of bone & joint, skin & soft tissue, bronchitis & other lower resp tract
infections; UTI, gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis. Surgical infection
prophylaxis
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION: GI disturbances including diarrhea, nausea & vomiting. Rarely erythema
multiforme; Stevens-Johnson syndrome & toxic epidermal necrolysis.

GENERIC NAME: celtriaxone na

BRAND NAME: groxone
INDICATION: Treatment of susceptible infections including chancroid, gastroenteritis (invasive
salmonellosis, shigellosis), gonorrhea, Lyme disease, meningitis (including meningococcal meningitis
prophylaxis), septicemia, syphilis, typhoid fever & Whipple's disease.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Changes in bowel flora; diarrhea (especially in childn); biliary sludge or
pseudolithiasis; hyperbilirubinemia; neutropenia.
GENERIC NAME: ceftzidime pentahydrate
BRAND NAME: hacef
INDICATION: Treatment of infection due to sensitive gm +ve & gm -ve bacteria.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Burning, discomfort & pain at inj site; diarrhea; elevated alkaline
phosphate, SGOT, SGPT; nausea & vomiting; +ve Coombs' test; pseudomembranous colitis; seizures
(large doses)

GENERIC NAME: cefimine hci,agrinine

BRAND NAME: hapimax
INDICATION: Treatment of infections due to susceptible organisms including UTI, resp tract & skin
infection.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Hypersensitivity reactions. +ve Coombs' test. Neutropenia,
thrombocytopenia & agranulocytosis. Preexisting renal impairment. GI disturbances. Pain at inj site &
thrombophlebitis.

GENERIC NAME: cefuroxime na

BRAND NAME: harox
INDICATION: Treatment of bone & joint infection, bronchitis, gonorrhea, meningitis, otitis media,
peritonitis, pharyngitis, sinusitis, skin disorders. Prophylaxis for surgical infection & UTI.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Skin rashes, urticaria, eosinophilia, fever, serum sickness-like reactions,
anaphylaxis. Bleeding complication related to hypothrombinemia &/or platelet dysfunction.
Nephrotoxicity. Acute renal tubular necrosis. Prolonged use. Pseudomembranous colitis.

GENERIC NAME: cefotaxime

BRAND NAME: haxim
INDICATION: Treatment of infections due to susceptible organisms that are serious & life-threatening.
Also used as prophylaxis for surgical infections.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Thrombocytopenia, eosinophilia, leukopenia, hypersensitivity reactions
& GI effects.

GENERIC NAME: ceftriaxone na

BRAND NAME: haxon
INDICATION: Treatment of susceptible infections eg chancroid, endocarditis, gastroenteritis,
gonorrhea, Lyme disease, meningitis, pneumonia, septicemia, syphilis, typhoid fever & Whipple's
disease. Surgical infection prophylaxis.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Pain, induration or tenderness at the site of inj. Rash, eosinophilia,
thrombocytosis & leukopenia. Diarrhea, elevated SGOT or SGPT & BUN.

GENERIC NAME: cefoxitin na

BRAND NAME: haxotin
INDICATION: Infections due to sensitive gm +ve & gm -ve bacteria; surgical prophylaxis.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Skin rashes, urticaria, eosinophilia, fever, reactions resembling serum
sickness & anaphylaxis; +ve Coombs' test; neutropenia & thrombocytopenia; bleeding complications,
nephrotoxicity, acute renal tubular necrosis, acute interstitial nephritis. CNS toxicity, convulsions;
pseudomembranous colitis. Pain at inj site & thrombophlebitis.

GENERIC NAME: cefazolin na

BRAND NAME: hazolin
INDICATION: Treatment of infections due to susceptible organisms including biliary tract infection,
endocarditis & peritonitis.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Pain at inj site. GI disturbances & hypersensitivity reactions. Allergic
reaction eg urticaria, pruritis, exfoliative dermatitis, morbilliform eruptions, rashes, drug fever, chills,
serum sickness & eosinophilia.

GENERIC NAME: ceftriaxone na

BRAND NAME: hoftrex
INDICATION: Treatment of infections caused by susceptible organisms eg bone & joint infections,
uncomplicated gonorrhea, intra-abdominal infections, Lyme disease, meningitis, otitis media, pelvic
infections (female), resp tract infections, bacterial septicemia, skin & soft tissue infections & bacterial
UTI.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Hypersensitivity reactions (eg fever, swelling, itching, rash, redness),
hematological changes (eg leukopenia, neutropenia, thrombocytopenia, agranulocytosis, aplastic or
hemolytic anemia), skin reactions (eg erythema multiforme or Stevens-Johnson syndrome) &
thrombophlebitis.

GENERIC NAME: cefazoli na

BRAND NAME: ilozef
INDICATION: Biliary tract & urogenital, resp infection, endocarditis, endometritis, peritonitis,
prophylaxis for surgical infection, pneumonia, cholecystitis, hepatic abscess. Septicemia, tonsillitis, otitis
media, pyelonephritis, phlegmon.
CHEMISTRY:
MODE OF ACTION:
ADVERSE DRUG REACTION:(AR) Skin rash, fever, urticaria, eosinophilia, serum sickness & anaphylaxis,
neutropenia, thrombocytopenia, nephrotoxicity, transient increases in liver enzymes, hepatitis,
cholestatic jaundice & convulsions. Nausea, anorexia, vomiting & diarrhea. Pain at IM inj site.