Professional Documents
Culture Documents
Pathophysiology Cholelithiasis
Pathophysiology Cholelithiasis
Precipitating Factors:
Predisposing Factors: Birth control pills
Female Low Fat Diet
Age 38 Pregnancy
Ethnicity Rapid weight loss
Diabetes Mellitus Obesity
fasting
Bile stagnates in the
gallbladder
Gallstones
CHOLELITHIASIS
Lumen is obstructed by
stones
Bile stasis
(Prostaglandins)
Fluids leak into Inflammation of the
gallbladder gallbladder
Edema
Increased intraluminal
pressure and distention Biliary Colic
of the gallbladder
(RUQ pain)
ACUTE CHOLECYSTITIS
If not treated
If treated with:
Continued lack of
Continued increase
blood supply to
Surgery, proper in intraluminal
gallbladder
diet (low fat, high pressure of
fiber), compliance gallbladder
to medications Necrosis
Rupture of gallbladder
Good prognosis Gangrene and empyema
Sepsis
Death