Sensitivity

Oxidation/reduction of TET (pantadreptei Linear

Sensor architecture LOD OBS Ref
(experimental conditions) de calibrare - range
slope)
adsorptive stripping
differential pulse
voltammetry between
4
modulation time = 0.5 s, 1.2 × 10 μA L 2.0 × 10− 5 and
1 GPE/MWCNT-COOH-GO 3.6 × 10− 7 mol L− 1 1
modulation mol− 1 3.1 × 10− 4 mol
amplitude = 75 mV, L− 1
ΔEs = 4 mV, Eacc = 0.2 V,
and tacc = 30 s
Comparatie
CV
GC, GC/ERGO-1.2V,
2 GC/ERGO-0.8V 50 mV/s 2
GC/CRGO, and
between –0.8 and +1.4 V
GC/GO
CV
3 MWCNT-GCE 50 mV/s * 3

GPE – carbon paste electrode; MWCNT-COOH – multi-walled carbon nanotubes functionalized with carboxyl groups; GO – graphene oxide
ERGO-0.8V – electrochemically reduced graphene oxide at –0.8 V; GCE – glassy carbon electrode;

* The use of multi-wall carbon nanotube modified electrodes produced an enhancement of the electrochemical oxidation responses
obtained for tetracycline antibiotics. This allowed amperometric detection of these compounds at the modified electrode to be
performed, exhibiting some advantages with respect to the use of other electrochemical detection methodologies. This improved
electroanalytical performance was exploited to develop an HPLC-EC method useful for the determination of tetracycline antibiotics in
water samples. Furthermore, the possibility of multiresidue analysis is also demonstrated
Refrences:

1. D.P.T.Sotomayor, A. W. (2015). Development and application of an electrochemical sensor modified with multi-walled carbon nanotubes
and graphene oxide for the sensitive and selective detection of tetracycline. Journal of Electroanalytical Chemistry , 250-257
https://www.sciencedirect.com/science/article/pii/S1572665715301405#bb0080

2. Sang, Y. X. (2015). Electrochemically reduced graphene oxide with enhanced electrocatalytic activity toward tetracycline detection.
Chinese Journal of Catalysis , 1936-1942
https://www.sciencedirect.com/science/article/pii/S1872206715609561#cesec110

3. Pingarrón, D. V.-C.-S. (2007). Voltammetry and amperometric detection of tetracyclines. Anal Bioanal Chem
https://www.researchgate.net/publication/6167099_Voltammetry_and_amperometric_detection_of_tetracyclines_at_multi-
wall_carbon_nanotube_modified_electrodes#pf7