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The World Health Organization (WHO) is revising the ICD-10 classification of mental and behavioural disorders, under the leadership
of the Department of Mental Health and Substance Abuse and within the framework of the overall revision framework as directed by the
World Health Assembly. This article describes WHO’s perspective and priorities for mental and behavioural disorders classification in
ICD-11, based on the recommendations of the International Advisory Group for the Revision of ICD-10 Mental and Behavioural Disor-
ders. The WHO considers that the classification should be developed in consultation with stakeholders, which include WHO member
countries, multidisciplinary health professionals, and users of mental health services and their families. Attention to the cultural frame-
work must be a key element in defining future classification concepts. Uses of the ICD that must be considered include clinical applica-
tions, research, teaching and training, health statistics, and public health. The Advisory Group has determined that the current revision
represents a particular opportunity to improve the classification’s clinical utility, particularly in global primary care settings where there
is the greatest opportunity to identify people who need mental health treatment. Based on WHO’s mission and constitution, the usefulness
of the classification in helping WHO member countries, particularly low and middle-income countries, to reduce the disease burden as-
sociated with mental disorders is among the highest priorities for the revision. This article describes the foundation provided by the recom-
mendations of the Advisory Group for the current phase of work.
The World Health Organization (WHO) is in the process national agreement on these issues and is therefore in a
of revising the International Statistical Classification of Dis- unique position to initiate and promote global health stan-
eases and Related Health Problems, currently in its tenth dards. WHO’s classification systems are the basis for track-
version (ICD-10). The WHO Department of Mental Health ing epidemics and disease burden, identifying the appropri-
and Substance Abuse is responsible for the revision of the ate targets of health care resources, and encouraging ac-
ICD-10 classification of mental and behavioural disorders, countability among member countries for public health at
within the overall framework of the ICD revision effort. The the population level. WHO’s classification systems are also
purpose of this article is to articulate WHO’s perspective and among the core building blocks for the electronic health in-
priorities for the ICD-11 mental and behavioural disorders formation systems that are of increasing importance in many
classification, based on the initial period of work by the In- countries.
ternational Advisory Group for the Revision of ICD-10 As a common classification framework, the ICD has fos-
Mental and Behavioural Disorders. tered global communication and information exchange. At
The WHO is a specialized agency of the United Nations the clinical level, classifications enable communication among
established in 1948, whose mission is the attainment by all health professionals, their patients, and the health systems
peoples of the highest possible level of health. The WHO has in which they work, and facilitate the training of health pro-
explicitly defined mental health as a part of health from its fessionals across countries and cultures. WHO classifica-
inception. WHO’s constitution (1), ratified by all 193 current tions also serve other sectors, including health policy mak-
WHO Member States, enumerates its core responsibilities, ers and payers of health care services, the judicial system,
which include: establishing and revising international no- and governments. Because the ICD plays such a crucial role
menclatures of diseases, causes of death and public health in the international health community, it is critical that it be
practice; and standardizing diagnostic procedures as neces- based on the best available scientific knowledge and that it
sary. Classification systems are therefore a core constitution- keep pace with significant advances in health care that have
al responsibility, which the WHO does not have the option the potential to improve its reliability, validity, and utility.
of devolving to other parties. The ICD is the oldest, most The ICD-10 was approved by the World Health Assembly in
central, and most historically important of WHO’s classifi- 1990 and published in 1992 (2), making the current period
cation systems. the longest in the history of the ICD without a major revi-
The purpose of the ICD is to serve as an international sion. The World Health Assembly, comprised of the health
standard for health information to enable the assessment ministers of all WHO member countries, has directed WHO
and monitoring of mortality, morbidity, and other relevant to revise the ICD-10. The technical work associated with the
parameters related to health. The WHO is the only organiza- preparation of ICD-11 is scheduled for completion is 2013.
tion with the ability to secure global cooperation and inter- It is envisioned that the World Health Assembly will ap-
3
In lower-middle income countries, there is an average of information considered as a basis for revising the ICD mental
about 1 psychiatrist per 100,000 population, and an average and behavioural disorders classification, with the goal of im-
of 2.7 in upper-middle income countries (6). proving its clinical utility and cultural applicability. First, a
Therefore, psychiatrists cannot be seen as the primary us- series of international and multilingual literature reviews
ers and the sole professional constituency for the classifica- have served to evaluate major trends, themes, and areas of
tion. Other professional groups should also have a meaning- active debate related to the classification of mental disorders,
ful and proportionate role in the process. This includes particularly concerning clinical utility in low and middle-in-
other mental health professionals such as psychologists, come countries. A second project has been a systematic
social workers, and psychiatric nurses. It also includes other analysis of country-level and regional diagnostic systems for
physician groups, especially primary care physicians, as well mental disorders (e.g., 9, 10), providing important data re-
as lay health care workers who deliver the majority of pri- garding which ICD elements are endorsed by local users as
mary and mental health care in some developing countries. useful, which are seen as lacking, and what additional cate-
For this reason, representatives of international professional gories and alternative disorder descriptions may be needed.
associations representing these groups have been included A third project has been a large survey of use and attitudes of
in the Advisory Group from the beginning. Geographic and psychiatrists of the various countries of the world concerning
linguistic diversity must also be addressed carefully in creat- diagnosis and classification of mental disorders, which has
ing mechanisms for participation, as in the past it has gener- been carried out in collaboration with the WPA (11).
ally been professionals from wealthier, usually Anglophone,
countries who have been most easily able to travel and par-
ticipate in meetings conducted in English. The influence of Uses of ICD-10 mental and behavioural
the pharmaceutical industry on some groups of profession- disorders classification
als must also be addressed seriously. In order to avoid undue
influence, the WHO considers that it is important to exam- The nature of changes that will be made in the course of
ine carefully possible conflicts of interest among participants the revision will be heavily influenced by the uses of the
in the revision of mental disorders classification and diag- classification that are considered important during the revi-
nostic criteria. sion process. Five main uses of the ICD-10 mental and be-
For the mental disorders classification in ICD, the WHO havioural disorders classification can be identified: clinical
recognizes the users of mental health services and their fam- uses; research uses; teaching and training uses; health statis-
ily members as a third direct stakeholder group. The user tics uses; and public health uses. How changes in the clas-
community in mental health has been increasingly aligned sification will influence its utility for all these purposes will
with the disability rights movement, adopting the motto of be an important focus of the revision process.
‘Nothing about us without us!’, rejecting what they see as
medical paternalism, and demanding to be consulted about
the decisions that affect their lives. The ICD revision process Clinical uses
must encompass substantive and serious opportunities for
participation of user groups, not just symbolic and ritualistic Past revisions have focused primarily on the use of the
gestures. At the same time, service user and family organiza- classification by mental health professionals, particularly
tions are not monolithic, but rather characterized by a wide psychiatrists, in specialty mental health settings. The WHO
diversity of perspectives and opinions. Opportunities must published a volume of Clinical descriptions and diagnostic
be created for broader input that are structured and timed so guidelines (3), primarily intended for such applications. But
that they contribute constructively to the revision process the ICD mental and behavioural disorders classification is
and are more than a political exercise. applied in a much broader range of settings - for example,
primary, secondary and tertiary medical settings, substance
abuse settings, and rehabilitation centres - and must be re-
Universality of categories sponsive to their needs.
From WHO’s point of view, the usefulness of the ICD
Universality of specific categories of mental disorders is an mental and behavioural disorders classification in primary
inherent assumption in ICD-10. This assumption has not care settings is one of the most important considerations in
been proven, however, and in spite of the repeated call for the current revision. By definition, primary care settings are
more attention to culture in psychiatric diagnosis by some those in which people are most likely to come into contact
authors, the issue of culture has largely been viewed as a with the health care system. Across the world, when people
distraction or source of error in classification (7). Attention with mental disorders do receive care, they are far more
to cultural framework cannot be optional but should become likely to receive it in primary care than in specialty mental
a key element in defining future classification concepts (8). health settings (12). Therefore, primary care settings repre-
The WHO and the Advisory Group have been pursuing sent the best opportunity to improve the identification and
several strategies for increasing the global scope and range of effective treatment of people with mental disorders.
5
Public health uses tioning may be affected by a health condition. The ICF was
designed to “provide a unified and standard language and
If the ICD-11 classification of mental and behavioural framework for the description of health and health-related
disorders is to be true to WHO’s constitution and charter, its states”. The ICF does not classify diseases, disorders, injuries,
public health application must be its most important orient- or health problems, which is the purpose of the ICD. The ICF
ing principle. The revision should seek to maximize the con- was designed as a complementary system, meant to be used
tribution of the classification to collective action for sus- together with the ICD, to classify the functional conse-
tained population-wide health improvement. More specifi- quences, components, or correlates of health conditions.
cally, as part of the revision process, consideration should be The approval of the ICF represents a policy basis for the
given to how the classification system can assist in: a) de- position that functional status and disability - those things
creasing the incidence and prevalence of mental disorders; that are categorized by the ICF - should not be part of the
b) decreasing disability associated with mental disorders; c) definitions and criteria for the diagnostic entities classified by
improving the accessibility and delivery of mental health the ICD. Another reason that this discussion has been an
services; d) promoting mental health; and e) evaluating pub- important focus of the Advisory Group is that differing con-
lic health needs and monitoring trends. ceptualizations of functioning and disability in relation to
The most important global challenge in mental health is diagnosis are one of the most significant differences between
what the WHO often refers to as the mental health gap (19). the ICD-10 mental and behavioural disorders classification
Neuropsychiatric disorders account for a greater share of and the DSM-IV (25). As noted earlier in this article, the Ad-
total global disease burden and disability than any other cat- visory Group endorsed the ICD-10 definition of a mental
egory of non-communicable disease (20). Yet, treatment re- disorder as a working definition for ICD-11. This definition
mains unavailable or woefully inadequate. In developing refers to functional impairment but does not require it, sim-
countries, fewer than 25% of people with even severe men- ply indicating that mental disorders often interfere with per-
tal disorders receive any treatment at all (21). Worldwide, sonal functioning. The clinical descriptions and diagnostic
the gap between those who need treatment and those who guidelines for ICD-10 mental and behavioural disorders (3)
receive it ranges from 32% to 78%, depending on the disor- provide more specific guidance, stating as a general princi-
der (22). In addition to the scarcity of mental health profes- ple that interference with the performance of social roles
sionals, other factors that contribute to the mental health (e.g., family, employment) should not be used as a diagnostic
gap include the under-resourcing of mental health care sys- guideline or criterion.
tems, issues of stigma, inadequate prevention programming, Üstün and Kennedy (26) have proposed an even stricter
and lack of parity in health financing including through in- separation of functional status and diagnosis than character-
surance coverage (23). izes ICD-10: “No functioning or disability should appear as
To address the mental health gap, WHO considers the part of the threshold of the diagnosis... A separate rating of the
development of more accessible and less stigmatized ser- disorder severity (i.e., mild, moderate, or severe), after a diag-
vices, that reach more of the population in need and in- nosis has been made, would rely on an assessment of the de-
crease the population impact of services for mental health velopment of the disease, its spread, continuity or any measure
and substance abuse disorders, to be an urgent priority. Cur- independent of disability parameters, so as to avoid co-linear-
rently available services often bear little relation to those ity”. The Advisory Group, however, suggested that the ability
with sound scientific support that may be more cost-effec- to make this distinction is less than perfect given the current
tive. In order to improve the quality of mental and substance state of science and clinical practice, citing the general lack of
use disorder treatment at a population level, the allocation direct, objective disease indicators for mental disorders as well
of limited intervention resources should be brought more in as the continuity of some phenomena considered to represent
line with the epidemiology, natural course and disease bur- mental disorders with normal variations in behaviour. Conse-
den of these disorders. The ICD is an integral part of such quently, in some specific diagnoses it may be necessary to refer
an effort. People are only likely to have access to the most to specific types of functional impairment as thresholds for
appropriate mental health services when the conditions that separating disorder from non-disorder when more “direct” in-
define eligibility and treatment selection are supported by a dicators of disease processes are not available.
precise, valid, and clinically useful classification system. Therefore, the Advisory Group has recommended that
the reformulation of diagnostic definitions, descriptions,
and criteria so as to exclude the phenomena considered to
Disentangling diagnosis and the functional be representative of functional impact be undertaken where
impact of mental disorders possible, and categories where it is not possible be clearly
identified. If an inference about an underlying pathological
In 2001, the World Health Assembly approved the Inter- phenomenon is being made based on a distinctive pattern of
national Classification of Functioning, Disability, and Health functional disturbance, this should be made explicit. The
(ICF) (24). The ICF provides a systematic and universal Advisory Group also noted that the development of valid
framework for describing the ways in which human func- and systematic methods for assessing functional status is a
7
The conceptual decisions and recommendations of the sis. Psychopathology 2005;38:192-6.
Advisory Group discussed above have provided a solid 8. Alarcón RD. Culture, cultural factors, and psychiatric diagnosis: re-
view and projections. World Psychiatry 2009;8:131-9.
foundation for the current phase of work on the ICD revi- 9. Chen Y-F. Chinese Classification of Mental Disorders (CCMD-3):
sion. We look forward to even greater collaboration with our towards integration in international classification. Psychopathology
international colleagues as we proceed with the develop- 2002;35:171-5.
ment of ICD-11. 10. Otero-Ojeda AA. Third Cuban Glossary of Psychiatry (GC-3): key
features and contributions. Psychopathology 2002;35:181-4.
11. Reed GM, Maj M, Correia J et al. The WHO-WPA global survey of
psychiatrists’ uses and attitudes toward mental disorders classifica-
Acknowledgements tion. World Psychiatry 2011;10:xx-xx.
12. Wang PS, Aguilar-Gaxiola S, Alonso J et al. Use of mental health
This article is based largely on the discussion and reports of services for anxiety, mood, and substance disorders in 17 countries
the International Advisory Group for the Revision of ICD-10 in the WHO world mental health surveys. Lancet 2007;370:841-50.
13. World Health Organization. Diagnostic and management guidelines
Mental and Behavioural Disorders during the period from
for mental disorders in primary care: ICD-10 Chapter V Primary
2007 to 2010. Members of the Advisory Group during the Care Version. Göttingen: Holgrefe, 1996.
period have included S.E. Hyman (Chair, 2007-2010), G. An- 14. Gask L, Klinkman M, Fortes S et al. Capturing complexity: the case
drews (2007-2008), J.L. Ayuso-Mateos (2009-2010), W. Gaeb- for a new classification system for mental disorders in primary care.
el (2009-2010), D.P. Goldberg (2007-2008), O. Gureje (2007- Eur Psychiatry 2008;7:469-76.
15. Westen D, Novotny CM, Thompson-Brenner H. The empirical sta-
2010), A. Jablensky (2009-2010), B. Khoury (2009-2010), A.
tus of empirically-supported psychotherapies: assumptions, find-
Lovell (2009-2010), M.E. Medina Mora (2007-2010), A. Rahi- ings, and reporting in controlled clinical trials. Psychol Bull 2004;
mi-Movaghar (2009-2010), K. Ritchie (2007-2008), K. Saeed 130:631-63.
(2007-2008), N. Sartorius (2007-2010), P. Sharan (2009-2010), 16. Hyman SE. The diagnosis of mental disorders: the problem of reifi-
R. Thara (2007-2008), P. Udomratn (2009-2010), Xiao Zeping cation. Annu Rev Clin Psychol 2010;6:155-79.
17. Insel T, Cuthbert B, Garvey M et al. Research domain criteria
(2009-2010) and Yu Xin (2007-2008). Organizations repre-
(RDoC): toward a new classification framework for research on
sented on the Advisory Group have included the Internation- mental disorders. Am J Psychiatry 2010;167:748-51.
al Federation of Social Workers (R. Blickle-Ritter, 2007-2008; 18. World Health Organization. The ICD-10 classification of mental
S. Bährer-Kohler, 2009-2010), the International Council of and behavioural disorders: diagnostic criteria for research. Geneva:
Nurses (A. Coenen, 2007-2008; T. Ghebrehiwet, 2009-2010), World Health Organization, 1993.
19. World Health Organization. mhGAP—Mental Health Gap Action
WONCA (M. Klinkman, 2007-2010), the World Psychiatric
Programme: scaling up care for mental, neurological, and substance
Association (J. Mezzich, 2007; M. Maj 2008-2010), and the use disorders. Geneva: World Health Organization, 2008.
International Union of Psychological Science (G. Reed, 2007; 20. World Health Organization. The global burden of disease: 2004 up-
A. Watts, 2008-2010). Principal members of the WHO Secre- date. Geneva: World Health Organization, 2008.
tariat working with the Advisory Group have included B. 21. World Health Organization World Mental Health Survey Consor-
tium. Prevalence, severity, and unmet need for treatment of mental
Saraceno, S. Saxena, G. Reed, S. Chatterji, and V. Poznyak.
disorders in the World Health Organization World Mental Health
Unless specifically noted, the views and ideas expressed in this surveys. JAMA 2004;291:2581-90.
article reflect the discussion and recommendations of the Ad- 22. Kohn R, Saxena S, Levav I et al. The treatment gap in mental health
visory Group and not the official policies or positions of the care. Bull World Health Organ 2004;82:858-66.
World Health Organization. 23. Saxena S, Thornicroft G, Knapp M et al. Resources for mental
health: scarcity, inequity, and inefficiency. Lancet 2007;370:878-89.
24. World Health Organization. International classification of function-
ing, disability and health. Geneva: World Health Organization, 2001.
References 25. First MB. Harmonisation of ICD-11 and DSM-V: opportunities and
challenges. Br J Psychiatry 2009;195:382-90.
1. World Health Organization. Basic documents, 46th edition. Gene- 26. Üstün B, Kennedy C. What is ‘functional impairment’? Disentan-
va: World Health Organization, 2007. gling disability from clinical significance. World Psychiatry 2009;8:
2. World Health Organization. International classification of diseases 82-5.
and related health problems, 10th revision. Geneva: World Health 27. Rounsaville BJ, Alarcón RD, Andrews G et al. Basic nomenclature
Organization, 1992. issues for DSM-V. In: Kupfer DE, First MB, Regier DA (eds). A re-
3. World Health Organization. The ICD-10 classification of mental search agenda for DSM-V. Washington: American Psychiatric As-
and behavioural disorders: clinical descriptions and diagnostic sociation, 2002:1-29.
guidelines. Geneva: World Health Organization, 1992. 28. Hyman SE. Can neuroscience be integrated into the DSM-V? Nat
4. American Psychiatric Association. Diagnostic and statistical manu- Rev Neurosci 2007;8:725-32.
al of mental disorders, 4th ed., text revision. Washington: American 29. Kendell R, Jablensky A. Distinguishing between the validity and util-
Psychiatric Association, 2000. ity of psychiatric diagnoses. Am J Psychiatry 2003;160:4-12.
5. American Psychiatric Association. Diagnostic and statistical manu- 30. First MB. Clinical utility in the revision of the Diagnostic and Statis-
al of mental disorders, 3rd ed. Washington: American Psychiatric tical Manual of Mental Disorders (DSM). Professional Psychology:
Association, 1980. Research and Practice 2010;41:465-73.
6. World Health Organization. Mental health atlas 2005. Geneva: 31. Andrews G, Goldberg DP, Krueger RF et al. Exploring the feasibility
World Health Organization, 2005. of a meta-structure for DSM-V and ICD-11: could it improve utility
7. Kirmayer LJ. Culture, context and experience in psychiatric diagno- and validity? Psychol Med 2009;39:1993-2000.