HAAD Exam 8 June 2017

1-

Drawing as in the exam exactly

(1) MTC also known as :
a. maximum toxic conc.
b. minimum safe conc.
c. maximum safe conc.
d. minimum effective conc.
answer.. C

(2) MEC mean :

a. minimum effective conc

(3) DRUG above MTC will show :

a.toxicty
b.side effect
answer ..A
(4)Drug below MEC will be :
a. toxic
b. ineffective
answer..B

(5) CMAX. :
a.maximum conc. of the drug to reach max.
b. tmax. to reach drug max. in plasma conc.
answer..A ( or ..max. drug conc. in plasma ...or. max. serum
conc. )

(6)TMAX. :
a. max. time to reach drug max. conc.
b. time required to reach max. plasma conc.
answer..B

(7) conc. at CMAX. is 23.5 ,the T will be:

a. 2hrs
b.3hrs
c.4hrs
d.5hrs
answer..B

(8)TOtal time of drug remain in the body :

- 24hrs
 (9)regarding prazocin:

Have first dose effect I

Most patients not developed tolerance to this effect Ii

First dose effect not decrease with decreasing dose Iii

Not usually occur in most patients Iv

answer ...i.have first dose effect

(10) the cough in ACE inhibitors ,Except :

a. accumulation of bradykinine
b. In women more than men
c. appears n 6 months
d. dose related
answer...D

(11)patient with hypertension put on antihypertensive drug, after

few months developed heart failure manifested as reduction in
heart rate and contraction, which antihypertensive drug patient
put on:
a. Lisinopril
b. verpamil
c. prozosin
d. Thiazide diuretic
answer.. B

(12)Mechanism of action of Digitalis all is true expect :

a. inc. contractility
b. dec. vascular resistance
c. reduse ventricular rate in atrial fibrillation
d. have modify effect on central nervous system
answer.. B

(13) patient admitted to ER with chest pain, diagnosed as

prinzmetal angina ,regarding this angina which is true :

a.Occur at rest not associated with physical activity

b.Associated with artery spasm

c.Associated with atherosclerosis

d.Not responsive to nitroglycerin and CCB

answer...all true except D

(14) Nitroglycerin not use in route of administration :

or .(about nitroglycerin least favorable route of administration :)

a. oral

b. buccal

c.Transdermal

d. sublingual

answer... A

(15)side effect of all anti-arrythmic :

a.blurred vision

b. torsade de points

answer.. B

(16) old patient admitted with arrhythmia ,regarding arrthmia

which is true:

a.most common cause is re-entry

b.antiarrythmia more safer

c.most ttt is CCB and NA channel blocker

d.SA is pace of heart contraction

answer..A ,C,D --TRUE

(17)Advantage of IV route is true: (without except)

a.used in emergency

b.dose can be titrated

c.fastest

d. safe and convenient

answer..A ,B,C---TRUE

(18)Foam in pharmacy spray:

a. Topical

b.Burn dressing

c. Rectal

d. all

answer...D

(19) If dose of drug is 0.2 ml ,How many dose will be in 15ml :

answer.. 15ml /0.2 ml =75 ml

(20)How many gram of 5% ointment will be prepared from 2 gm

answer.. (5%= 5gm ----100 ,,2gm---?

2*100/5=40 gm

(21) How many gram will be in 250 ml of 5% solution :

answer.. 5% = 5gm ---100ml

??--------250ml

= 250 *5 /100=12.5 gm

(22)Particle size affect the following :

a.solubililty b.dissolution

c.content-content uniformity

d.suspend abililty e.penetrability

answer...ALL

(23) Aiprazolam (CDA) :

answer... in steel cupboard well closed well(in my exam )

another answer... steel cupboard well closed with single lock

(24) Regarding Fluxetine :

a. half life is 50 hrs

b. have a metabolite as active as the prodrug

c. used in bulimia nervosa

d.undergo first pass effect

answer... ALL

(25) Case scenario about female patient have Chronic GOUT was

weak & dizzy & fatigue and another problems like she can’t raise

her hand and having some blood disorders like agrnaulocytosis and

leucopenia with hematouria and proteinurea which anti gout

are probably to cause this Side effects :

a-allopurinol

b- colchicine

c- probencid

answer... B (SURE)

(26)Pt. have lower HDL and lower dyslipidemia managment :

a. atrovastatin

b. Niacin

c. fenofibtates

d.Rosuvastatin

answer... B

(27)chest x ray show what like to cause this infection :

answer... MYcobacterium avium complex.

(28)BEES bites and symptom scheck , itching :

answer.... Epinephrine

(29) prevent remission in IBD :

answer... INfliximab

(30) conductivity test ,dilution test, dye test used for :

a- Suspension

b- Emulsion

c- Foam

d- Gel

answer...B

(31)Morphine cause tolerance except :

a- Rispiratory depression

b- Euphoria

c- Pint point pupil

answer... C ( least tolerance ..pint point pupil)

N.B: MOrphine cause tolerance (without except):

answer..1- euphoria 2- respiratory depression

(32) safe for pregnancy or can use for pregnancy:

answer... carbamazepine

N.B: used for Seizure in pregnancy : 1-carbamazepine

2-Clonzepam

(33)patient with acute mania , which drug isn’t effective:

answer... phenytoin
N.B: NOT USE OR NOT Effective :

1- phenytoin 2- chlorpromazine

USED IN TTT. : 1-lithium 2-Valproate 3-carbamazepine

4-lamotrigine

(34) all can use in acute Mania ,Except :

answer.. chlorpromazine

(35) ttt. of STatus Epilepsy :

answer... phenytoin

N.B: used in ttt: 1- benzodiazepines (diazepam)

2- Clonazepam 3- phenytoin

(36) - IN absence seizure all of the following prescribed except:

(OR NOT USE):

a- ethosuxamide

b- diazepam

c- lamotrigine

d- carbamezapine

answer.... D
N.B: NOT USED: 1- carbamazepine 2- phenytoin

USED IN TTT. :1- Ethosuximide 2- lamotrigine

(37)-patients with blood pressure 220/150 and glaucoma which

drug should be avoided:

a-labetalol

b-fendolopam

c-Na nitropuroside

d-nitroglycerin

answer... B

(38)SIADH cause all of the following except:

a-hyponatremia

b-hypernatremia

c-water excess

d-Inadequate vasopressin production

answer... B

(39)Ipratropium approved for :

a-maintaining COPD

b-asthma

answer... A
(40)-For treating morphine dependence all of the following

except :

a-Buprenorphine

b-clonidine

c-codiene

d-methadone

answer.... C

(41) patients admitted with morphine over dose what is the

appropriate treatment:

answer... Naloxone

(42) --Meperidine not suitable for use long time beacuse:

Nephrotxicity

b- Neurotoxicity

c- Cardiotoxicity

answer... B

(43)case : - TCA mechanism inhibit :

answer.... SSRT AND NE

(44) TCA metabolized by :

answer... CYP450
(45) TCA act on all ,EXCEPT :

a. alpha adrenoreceptor

b. beta adrenoreceptor

c.Muscrinic receptor

d. Histamine receptor

answer... B

(46) TCA used in all except :

panic attack
b-schizophrenia
c-Migrain
d- Neuropathic pain

answer... B

(47) DOSE pt.75 mg ,How ml. 125mg /5ml solution :

answer.... 125mg -----5ml

75mg ------??

= 75 *5/125=3ml

(48)patient with infection sensitives to tetracycline , pt is renal

impaired Which one of tetracyclines is suitable for him:

a- Doxycycline

b- Minocycline

c- Tetracycline

answer.. A

(49)patient with pharyngitis, the pt was penicillin allergic but

the organism is penicillin sensitive ,injectable abtibiotics is not

preferred in this situation ,what is the safest and effective

alternative :(bs el case kant mo5telfa )

a- Penicillin

b- Cephalosporin

c- Azithromycin

d- Tetracycline

(50) phenytoin S.E. all , Except :

a-gingival hyperplasia

b-nystagmus

c-nephrotoxicity

d-steven-gohnson syndrome

answer.... C

(51) Bacteria move by :

answer... Flagella

(52) NOT Fungus :

 answer.... E.COLI

(53) case : parkinson :

Tremor & agitation i

difficulty to initiate & voluntary movements ii

abnormalities in postural and normal position iii

answer ... ALL

(54) carvidopa used with levodopa to:

answer... inhibit peripheral conversion to dopamine

(55)effect of levodopa decreased with which vitamin:

a-B12

B-B6

C-B2

D-B3

answer... B

(56)effect of levodopa on body diminished :

a- after less than 3 yrs

b-after 2 yrs
c-after 3 yrs up to 5 yrs

d-after 5 yrs

answer.. C

(57) drug not used in Parkinson:

a-levodopa

b-bromocriptine

c-Chlorthalidone

d-MAOI

answer... C

N.B.: NOT USE IN PARKINSON:

( 1- Chlorthalidone 2- Chlorpromazine 3- Halopridol )

(58)high Therapeutic index mean:

answer... no side effect

(59)B adrenergic agonist least effect+:

answer... begin prostatic hypertrophy

(60) TB. medication ,INH,PYZ,RMP ,which is the SE. of INH :

answer... peripheral neuropathy

(61) Affect dissolution rate, absorption rate, content uniformity

and stability:
a. particle size

b. size distribution

c. interaction with surface molecule

d. all

answer... D

(62)antiviral used for influenza and , Parkinson:

a-amantidine

b-lamuvidine

c-zidovudine

answer.... A

(63)mitochondrial toxicity,, ANTIVIRUAL used:

a-lamivudine

b-amatidine

c-zidovudine

answer.... C (N.B. : 1- Stavudine 2- Zidovudine)

(64) antiviral used in HBV:

a-lamivudine

b-amatidine

c-zidovudine
d. stavudine

answer... A

(65)patient with HIv , the CD4 less than:-

a-200

b-400

c-500

d-600

answer... A

(66)CD4 bind to which antigen in the HIV positive Pt:

a-T lymphocyte

b-B lymphocyte

c-macrophages

d-natural killer

answer... A

(67)50% alchohol is to be diluted with purified water, how many

parts of purified water (0% alchohol) to prepare 20%

preparation:

a- 30parts water + 20 parts 50% alchohol.

b-30 part alcohol +20 part water.

c-50 part alcohol+50 part water

answer... A

(68)charcoal used in poisoning due to which properties:

a-adsorption

b-absorption

c-metabolism

d-excretion

answer... A

(69)non-competitive ACH except :

a-rivastigmine

b-Tacrine

c-donazepil

d- galantamine

answer... D

(70)which is true about dry gum emulsion:

a-ratio 4:2:1

b-water gum and oil are added together and triturated slowly

c-oil and gum are triturated and water added slowly

answer.. A

N.B.: DRY : gum and oil are triturated and water added at once

WET : gum and water are triturated and oil added slowly
(71) q about emulsion inversion

a-conversion of W/O emulsion to O/w emulsion and vice versa

72- long case have arrhythmia+ COPD can use except

a-digitalis

b-verpamil

c-amiodarone

d-diltiazem

73- mydratic used to determine the true refractory error of the

eye

a- Atropine

b- Tropicamide

74- pilocarpine used in all of the following except:-

a-acute attack of closed angle of glaucoma

b-standard drug for close angle glaucoma

c-used alternatively with mydriatic to separate the iris

d-standard one for open angle glaucoma✔

75- used for parnzmetal angina except

76-Not used in prinzmetal Angina:

A. Losartan
B. CCB

C. Nitrate

D. B blockers

77-question all about immune reconstitution inflammatory

syndrome except

a-not effected by glucocorticoids or antiinflammatories

c- the action of antiviral starts

d- the patient start to respond to ttt

78- Pt is taking anti-seizure medication and wants to stop it, which

of the following low recurrence:-

a- EEG abnormalities

b-frequent seizure attack

c-cerebral known lesions

d-seizure began at early age✔

79- In mysthenia gravis which is true except:

A. Autoimmune disease againtACh receptors

b. Diagnosed by edrophonium

C. Not treated with cortitcosteroids

This is all about the Exam

It was so easy Al-Hamduleilah and most of calculation was direct

‫وال تنسونا من صالح دعائكم‬

‫ محمد رجب‬.‫د‬