PEMERIKSAAN

SEDIAAN HAPUS DARAH TEPI DAN SUMSUM TULANG

No.Dokumen: No. Revisi: Halaman:
/SOP/RSUDM/I/2014 02 4/4

TIM SOP Tanggal Terbit: Ditetapkan

LABORATORIUM Direktur,
7 JANUARI 2014

Feby Levarina,dr.,Sp.PK.,M.Kes
Nip. 19680218 200212 2 002
PROSEDUR FAB SCORING SYSTEM FOR L1 AND L2 VARIANTS
Criteria Score
High N/C ration > 75% of cells +
Low N/C ratio > 25% of cells -
Nucleoli : 0-1 (small) > 75% of cells +
Nucleoli : 1 or more (prominent) > 25% of cells -
Irregular nuclear membrane > 25% of cells -
Large cells > 50% of cells -

Criteria which are not met (or intermediate results). Result in no score. The possible total
score for a case ranges from –4 to +2. A score of 0 to + 2 results in a diagnosis of L1 and a
score of –1 to –4 in a diagnosis of L2
Cytologic L1 L2 L03

Cell SIZE Small cells pre Large; Large and

dominate heterogenneous in hemogenous
size
Nuclearchromatin Homogeneous in Variable, Finely stippled ang
Any one case helerogeneous in any homogeneous
One care
Nuclear shape Reguler,occsional Irreguler, cleting and Oval to reguler
cleting or Identation common
indetation
Nucleoli Not visible, or One or more present Prominent, one or
small Offen lareg More vesiculer
And incospicucus
Amount of Scanty Variable, offen Moderately abudant
cytoplasm Moderately abudant
Basophlia of Slight or Vriable, deep in some Very deep
cytoplsm moderate,rarely
intense
Cytoplasmic Varible Variable Often prominent

UNIT TERKAIT 1. Penata Laboratorium

2. Dokter