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Catatan Genmol 21 Oktober
Catatan Genmol 21 Oktober
Genotype: the genetic constitution of a cell or organism, it can refer to single or multiple genes
Phenotype: the observable characteristics of a cell or organisms including the result of test and
measurements
Gene: a hereditary unit, functional DNA unit, a factor that controls a phenotype and segregates in
pedigrees
2. a “changed” gene
Recombinant: a gamete that contains a combination of allelles that is different from the
combination inherited by parents
Darwinian school
Approah : Holistic
Mendelian School
Approach : Reductionist
Forward genetics : orang liat suatu mutan, kemudian diliat apa yang berubah dari struktur genetic
nya
Reverse genetics : orang merekayasa suatu gen tertentu, kemudian melihat apa yang terjadi setelah
suatu gen diubah
FORWARD GENETICS
Mutants in Arabidopsis :
1. Recessive mutations
2. Mutations in a single gene
3. Mutation affecting two adjacent whorls
4. Homeotic mutations
A. Normal, gen A B dan C diekspresikan, jadinya normal
B. Pistillata, gen B tidak diekspresikan, jadinya mutan
C. Agamous, gen C tidak diekspresikan, jadinya mutan
MUTATIONs
Type of mutation
Recessive
Dominant
Semidominant
Apakah di eukariotik, pembacaan RNA dapat dilakukan pada rantai template dan non-template?
Concept of Polymorphosms
FIND!
1. Overlapping gene
2. Frameshifted gene
3. Nested gene