All India Institute of Medical Sciences Bhopal

Institutional Human Ethics Committee

COVERING LETTER

To,
The Dean Research
AIIMS Bhopal

Subject: Submission of intramural research project proposal for review

Respected Sir,
Hereby, I am submitting proposal for intramural research for review titled “An audit of male factor
infertility at a newly established tertiary care centre in Central India”. Kindly accept by submission
for the needful.
Thanking You,
Regards,
Dr Tanya Sharma
Assistant Professor,
Department of Pathology and Lab Medicine

Date: 10.8.19

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 All India Institute of Medical Sciences Bhopal
Institutional Human Ethics Committee

Print copy of the following documents are attached for review

N Documents Attached
(Yes/No/NA)
1 Covering letter duly forwarded by Head of Department √
2 Completed Proforma of IHEC, AIIMS Bhopal V
3 Detailed protocol with the budget √
4 Brief 2 page CV of Investigators (including number of projects with Principal √
Investigator)
5 Investigator Assurance form √
6 Undertaking that the scales/questionnaires/scores to be used are not √
copyrighted or permission to use them has been obtained
7 In case of multicentric study, IEC clearance of other centres must be provided NA
8 Definite undertaking as to who will bear the expenditure of injury related to √
the project
9 In case an insurance cover is intended, insurance certificate must be provided NA
(as per ICMR guidelines)
10 Investigator should provide undertaking what they will do with the leftover √
sample tissue.
11 Soft copy of all the documents in PDF format by email √
(ihec@aiimsbhopal.edu.in)
12 Any other document
Thanking you,

Name

Dr Tanya Sharma

Assistant Professor, Department of Pathology and Lab Medicine

Signature

Submit a print copy and email PDF (single scanned copy) to ihec@aiimsbhopal.edu.in

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 All India Institute of Medical Sciences Bhopal
Institutional Human Ethics Committee

Investigator Assurance

I certify that information provided by me is complete and correct.

I understand that as Principal Investigator, I will take full responsibility for the protection of
rights and welfare of all trial subjects including the conduct of study and ethical performance
of the project.

I agree to comply will all rules and regulations of IHEC and All India Institute of Medical
Sciences Bhopal regarding conduct of the trial/ research project. I hereby declare.

 Qualified persons according to IHEC will conduct the study.

 No change will be made in the protocol or consent form until approved by the IHEC.
 Legally acceptable informed consent will be taken
 Adverse events will be reported to IHEC as per ICH GCP / DCGI Adverse event
reporting policy.

I further certify that the proposed research is not currently being conducted and will not
begin until IHEC approval has been obtained.

Investigators (affiliations) Signature Date

Principal Investigator

Dr Tanya Sharma

Co – Investigators

Dr Hemlata Panwar

Dr Sheetal Rathi

Dr Garima Goel

Dr Deepti Joshi

Dr Neelkamal Kapoor

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Institutional Human Ethics Committee

Format for submission of proposal to IHEC, AIIMS Bhopal (Version 1.2)

SL. ITEM
NO
1 Full title of the study: “An audit of male factor infertility at a newly established tertiary care
centre in Central India”

2 Name and role of Investigators/co-investigators with designation, departments and

signatures:
Principal Investigator
Name- Dr Tanya Sharma
Designation and department- Assistant Professor, Pathology and Lab Medicine
Role- Overall execution, literature search and manuscript preparation.
Signature-

Co – Investigators
Name- Dr Hemlata Panwar
Designation and department-Assistant Professor, Pathology and Lab Medicine
Role- Literature search, manuscript preparation
Signature:

Name- Dr Sheetal Rathi

Designation and department- Senior Resident, Pathology and Lab Medicine
Role- Literature search, Data collection, record maintenance, manuscript preparation
Signature-

Name- Dr Garima Goel

Designation and department- Associate Professor, Pathology and Lab Medicine
Role- Supervision and manuscript editing
Signature-

Name- Dr Deepti Joshi

Designation and depatment- Additional Professor, Pathology and Lab Medicine
Role- Overall supervision and manuscript editing
Signature-

Name- Dr Neelkamal Kapoor

Designation and department- Professor and Head, Pathology and Lab Medicine
Role- Conception, planning and guidance of project
Signature-

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3 Email ID and contact number of the Principal investigator:

tanya.patho@aiimsbhopal.edu.in
8224922257

4 Objectives of the study:

1. To study the prevalence of male factor infertility in patients presenting with infertility.
2. To study the profile of parameters of semen analysis in patients presenting with
infertility.
5 Justification of the study:
According to the International Committee for Monitoring Assisted Reproductive Technology,
World Health Organization (WHO), infertility is a disease of reproductive system defined by
failure to achieve the clinical pregnancy after 12 months or more of regular unprotected sexual
intercourse [1]. Infertility affects 8–12% of couples worldwide, out of which, approximately
40–50% is due to “male factor” infertility [2]. Semen analysis is a fundamental diagnostic
tool in the evaluation of the male partners of infertile couples. Careful evaluation of the
seminal parameters may suggest the possible causes of infertility and their identification could
help to institute appropriate therapy.
There are no reliable figures for global prevalence of infertility, but estimates suggest that
nearly 72.4 Million couples globally experience fertility problems [3]. To the best of our
knowledge, there is scarcity of data highlighting the profile of male factor infertility in central
India [4]. The present study will highlight upon the prevailing status male factor infertility and
the profile of abnormal seminal parameters in this region.

6 STUDY PROTOCOL

Study design-Cross Sectional Retrospective observational Study

Study settings- Department of Pathology and Lab Medicine, AIIMS Bhopal

Study duration- From February 2017 till July 2019

Methodology:

Inclusion criteria:
All semen samples received for analysis in Department of Pathology and Lab Medicine for
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Institutional Human Ethics Committee

infertility.

Exclusion criteria:
All semen samples received for semen analysis for cause other than infertility like post-
vasectomy specimens.

Sample collection:
Semen specimens collected by masturbation after 3–5 days of sexual abstinence in standard
sterile container will be collected by patient. The patient will be given instructions concerning
the collection of the semen sample that the sample needs to be complete and that the man should
report any loss of any fraction of the sample. Sample collection should be done in laboratory
premises.

Transport to laboratory: The specimen is then submitted by patient within half an hour of
collection.

Semen Analysis:
 Sample is analysed following liquefaction, using automated semen analyzer SQA-
Vision,
as per standard operating procedure
 Relevant clinical details of patient will be noted by pathology technician /pathologist
o Age of husband and wife
o Years of marriage
o No. of children
o Obstetrics history of wife
o Mode of contraception used previously/presently
o History of alcohol and smoking
o Any other medications
o History of chronic illness-TB, Diabetes, Hypertension, etc

 Semen analysis involves the following steps

 In the first 5 minutes:
 Placing the specimen container on the bench or in an incubator (37 °C) for liquefaction.
 Between 30 and 60 minutes:
 Assessing liquefaction and appearance of the semen.
 After liquefaction for 30-–60 min at room temperature, following parameters will be
noted
1. Volume
2. Appearance
3. Viscosity
4. pH (pH strip)
5. Preparing a wet preparation for assessing microscopic appearance, sperm motility and
the dilution required for assessing sperm number. Wet mount, stained smears and
Neubeaurs chamber preparation of sample for examination prepared according to SOP
Clinical pathology in department will be prepared and studied by two observers
6. White blood cells (>1×106/ml or (< 1×106/ml )will be noted on wet mount of sample by
reporting pathologist and data shall be entered in SQA Vision and manually in case data

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sheet by two independent observers

7. Aggregation and its grading
8. Assessing sperm vitality as % assessed by identifying those with an intact cell
membrane, by Eosin Y dye exclusion method
9. Making semen dilutions for assessing sperm concentration[Spermatozoa
per ×400 field->101:1: 20 dilution, for 16–100 : 1:5 dilution, 2–15 :1: 1 dilution and all 3
central grids are assessed. For extremely low spermatozoa i.e <2 :all 9 grids will be
counted in a dilution of 1:1 (As per WHO manual)]
10. Total sperm concentration on improved Neubauer haemocytometer chamber and
total spermatozoa per ejaculate
11. Motility will be assessed after counting 200 sperms and graded as
o Progressive motility%
o Non progressive motility%
o Total motility: (PR+ NP)%
o Immotile%
 After 4 hours:
 Preparing direct or centrifuged wet fixed and papanicolaou stained smears for
assessing sperm morphology
 Teratozoospermic index (TZI)and Sperm deformity index (SDI)will be calculated
 In case no sperms are seen, a centrifuged deposit will be examined to conclusively
report azoospermia and a repeat sample will be advised to patient as mentioned in SOP
of clinical pathology
 All parameters will be assessed using strict criteria of WHO 5th edition semen analysis
[5].
Reference range for semen analysis according to WHO Reference 2010:
Parameter Normal cut-off range
Volume 2ml
pH 7.2
Liquefaction time 60 minutes
Total sperm concentration 15 Million/ ml

Total sperm number 39 Million/ejaculate

Vitality 58%
Total motility 40%
Progressive motility 32%
Morphology 4% normal forms
WBCs <1X106/ml

Statistical analysis:
All statistical analyses will be performed by using SPSS21.0 version software for Windows. P
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value less than 0.05 (<0.05) will be considered statistically significant.

7 Permission from Drug Controller of India (DCGI):

7a. Required/Not required NOT REQUIRED
7b. Received on:
7c.Application date:

8 Permission from DGFT:

9998a. Required/Not required NOT REQUIRED
8b. Received on:
8c. Application date:

9 Safety measures for proposed interventions

9a. Results of relevant laboratory tests NOT APPLICABLE
9b. Result of studies in humans

10 Plan(s) to withdraw standard therapy during the course of research: NOT

APPLICABLE

11 Plan(s) for provision of coverage of medical risks during the study period. NOT
APPLICABLE

12 How will you maintain the confidentiality of the subject?

An identification number will be assigned to all participants and their identity
will not be disclosed anytime during the study and description of results; as well
as while preparing the manuscript. The data collected from one
individual/household will not be shared by the other people of the
Village/community.

13 Funding : None
14 Participant information sheet: Retrospective study
Attached Hindi version No
Attached English version No
Other regional languages as applicable
Certified that Hindi version is true translation of English version

15 Participant informed consent sheet: Retrospective study; We request a waiver of consent .

Attached Hindi version No
Attached English version No
Other regional languages as applicable
Certified that Hindi version is true translation of English version
16 Conflict of interest among investigators: NO
17 In case of clinical trials provide the CTRI status: Not applicable
18 No. of projects already with the Principal investigator: See Annexure 1
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REFERENCES:

1. International Committee for Monitoring Assisted Reproductive Technology (ICMART)

and the World Health Organization (WHO) revised glossary of ART terminology, 2009.
Zegers-Hochschild F, Adamson GD, de Mouzon J, Ishihara O, Mansour R, Nygren K,
Sullivan E, Vanderpoel S, International Committee for Monitoring Assisted
Reproductive Technology., World Health Organization. Fertil Steril. 2009; 92:1520-4.
2. Mascarenhas MN, Cheung H, Mathers CD, Stevens GA. Measuring infertility in
populations: constructing a standard definition for use with demographic and
reproductive health surveys. Popul Health Metr. 2012; 10:17
3. International estimates of infertility prevalence and treatment-seeking: potential need
and demand for infertility medical care. Boivin J, Bunting L, Collins JA, Nygren KG. Hum
Reprod. 2007; 22:1506-12
4. Kumar N, Choudhari AR, Singh AK. Prevalence of Male Factor Infertility in Last Ten
Years at a Rural Tertiary Care Centre of Central India: A Retrospective Analysis. Indian
Journal of Obstetrics and Gynaecology Research. 2015;2 :132-136.
5. WHO laboratory manual for the examination and processing of human semen. Fifth
Edition, 2010.

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Annexure 1

Project report
Date: 31.07.2018
LOP Number: LOPSTS0148
Project Title: Utility of scrape cytology in rapid diagnosis of tumors
Duration of the project: STS project of 2Months duration Report: (Annual/Final)
Name and affiliation of the investigators:
PI- Sheetal Singhal (MBBS Student)
Guide- Dr Tanya Sharma, Assistant Professor, Pathology and Lab Medicine
Introduction: Rapid diagnosis of tumors is crucial as it decides upon the surgical management to be
undertaken. Frozen section, intraoperative fine needle aspiration cytology and imprint cytology are
used by the surgical pathology laboratories for rapid and intraoperative diagnosis of tumors. Facility to
perform frozen sections may be lacking in many setups. Further, intraoperative FNAC may not be
feasible or conclusive in all cases.
Objectives:
Brief Methodology:A prospective study was conducted to evaluate the utility of scrape cytology for
rapid diagnosis of tumors and to correlate the findings of scrape cytology with histopathological
findings. A total of forty cases with clinicoradiological diagnosis of neoplasia were included in the
study. Scrape smears were prepared from specimens received either in formalin or in normal saline and
stained by rapid Hematoxylin and eosin technique
Results and conclusion: There were 30 (75%) cases of benign lesions and 10 (25%) cases of malignant
lesions. Overall, the diagnostic accuracy of scrape cytology was found to be 95% with a sensitivity of
90 % (CI-55.50 to 99.75) and specificity of 96.7 %( CI-82.78 to 99.92). In the present study, we found
that scrape cytology is a reliable, cost-effective and fairly accurate cytodiagnostic technique for rapid
intraoperative diagnosis of tumors. The study highlights the merits and pitfalls of scrape cytology. The
material and knowledge obtained can be utilized as a teaching material and may help unveil diagnostic
cytopathological features of cytologically less encountered lesions.
Work remaining: None
Outcome: Publications, presentations (poster or platform), patents, others. Attachments of the same
Poster presentation at ICP-AIPNA 2019 at AIIMS Bhopal.
The project was (tick whichever is applicable with brief reason)
a) not initiated
b) discontinued before completion

The brief report shall not exceed two A4 size pages (excluding attachments) and submitted to IHEC,
AIIMS Bhopal through proper channel.
Font shall be Times New Roman, size 11, line spacing 1.
One hard copy signed by the PI shall be provided to the IHEC office and scanned copy (with signatures)
mailed to ihec@aiimsbhopal.edu.in.

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Time bound milestones:

 Time duration  Work Plan

 August 2019- October 2019  Obtaining ethics approval, Data
Collection

 November 2019-February 2020  Data Analysis, compilation of

results, manuscript preparation

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Budget Page- NA

Budget requirement with justification:

A. Contingency:

B. Consummables:

C. Minor equipment:

D. Any other (please specify):

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Institutional Human Ethics Committee

UNDERTAKING

This is to declare that the project titled “: “An audit of male factor infertility at a newly
established tertiary care centre on Central India” .The study does not include any
procedure which is injurious to the patient or breaches the confidentiality of the patient. Also,
residual human tissue will be discarded according to waste discarding policy of our institute.

Dr Tanya Sharma

Assistant Professor

Department of Pathology & Lab Medicine

AIIMS Bhopal

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Institutional Human Ethics Committee

Brief CV of Investigators

Principal Investigator

Dr Tanya Sharma, Assistant Professor, Department of Pathology and Lab Medicine

Email Id: tanya.patho@aiimsbhopal.edu.in

LIST OF PUBLICATION

1. Sharma T, Bhargava R, Sharma J, Sharma S. Lymphadenopathic form of solid

variant of alveolar rhabdomyosarcoma: A rare case report. J Cytol. 2014 Jul-Sep;
31(3): 168–170.
2. Sharma T, Garg N, Singh B. ABO blood group discrepancies among blood donors
in Regional Blood Transfusion Centre GTB Hospital, Delhi, India. Apheresis.
2014 Volume 50, Issue 1, Pages 75–80
3. Garg N, Sharma T, Singh B. Prevalence of irregular red blood cell antibodies
among healthy blood donors in Delhi population. Apheresis. 2014 Volume 50, Issue
3, Pages 415–417.
4. Sharma J, Bhargava R, Vinay Bharat V, Sharma T, Bansal R, Upreti S, Kansal R.
A study of spectrum of morphological changes in endometrium in abnormal uterine
bleeding. JARBS. 2013; 5: 370-75.
5. Ruchika *, Tanya S, S. HS, Prakash K, Nidhi V, Juhi S. A Study of Fine Needle
Aspiration Cytology of Intra-Abdominal Masses In And Around Davangere,
Karnataka. JARBS. 2013; 5(3): 290-293.
6. Enterobius vermicularis: An unusual cause of recurrent urinary tract infection in a
seven year old female-A case report & review of literature- Bhupeshwari Patel,
Tanya Sharma, Girish Chandra Bhatt, Bhavna Dhingra Bhan. Trop Doct
OnlineFirst, published on January 13, 2015
7. Sharma J, Sharma T, Bhatt GC, Bhargava R. Isolated cold abscess of the thigh in an
immunocompetent infant. Trop Doct. 2014 Feb 19.
8. Ghatt GC, Sharma T. Comments on "clinical profile and outcome of Japanese
encephalitis in children admitted with acute encephalitis syndrome".Biomed Res Int.
2014;2014:767538.

9. Bhatt GC, Sharma T, Agrawal PK, Dhingra B. Not a typical urinary tract infection: A
case of urethritis due to an exogenous oil instillation in penile urethra of an infant. Annals
of Tropical Medicine and Public Health2014. 7 (2), 148.
10. Bhatt GC, Bondre VP, Sapkal GN, Sharma T, Kumar S, Gore MM, Kushwaha KP,
Rathi AK. Changing clinico-laboratory profile of encephalitis patients in the eastern Uttar
Pradesh region of India. Trop Doct. 2012 Apr. 42:106-8.
11. Bhatt GC, Sharma T, Kushwaha KP. Concurrent infection of JE and mixed malarial
infection. J Pediatr Neurosci.2012 ;7 :52-4.

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12. Bhatt GC, Sharma T*. Letter to editor “Aseptic meningitis following intravenous
immunoglobulin therapy of common variable immunodeficiency. J Pediatr Neurosci
2012; 7:242-3.
13. Bhatt GC, Sharma T. Author reply. J Pediatr Neurosci 2013; 7: 241-2.
14. Bhatt GC, Sharma T. Letter to editor “Outbreak of hand, foot and mouth disease in
Bhubaneswar, Odisha. Indian Pediatr 2013; 50:250.
15. Sharma T, Singh B, Bhatt GC. Profile of deferral of blood donors at regional blood
transfusion centre in north India. Asian Journal of Transfusion Science 2013; 7:156-
157.
16. Bhatt GC, Sharma T, Kushwaha KP. Enterovirus 76 associated severe acute
encephalitic syndrome complicated by myocarditis and successfully treated with
intravenous immunoglobulin. Annals of tropical medicine and public health 2013;
5:594-596.
17. Sharma T, Joshi D, Khurana A,Vikas Gupta, Kapoor NK. Bilaterally enlarged parotids
and sicca symptoms as a presentation of sarcoidosis: Pivotal role of aspiration
cytology in diagnosis. J Cytol. 2015 ; 32: 281–83.
18. Khurana U, Joshi D, Santosh JA, Sharma T, Kapoor NK. Oligosecretory multiple
myeloma: a case report. Blood Res. 2016 Mar; 51: 63–65
19. Khurana U, Majumdar K, Kapoor NK, Joshi D, Goel G, Sharma T et al. Spectrum
of parasitic infections in centrifuged urine sediments from a newly developed
tertiary care centre in Central India.Journal Of Parasitic Dis. 2018, DOI:
10.1007/s12639-018-1043-6

CO-INVESTIGATORS

Dr Hemlata Panwar, Assistant Professor, Department of Pathology and Lab Medicine

Email Id: hemlata.patho@aiimsbhopal.edu.in

List of Publications:

S.N Title of Work Authors/ Coauthors Details of journal

o
1. Nodular cystic hidradenoma Panwar H, Santosh T, Med J DY Patil Univ 2017;
over the gluteal region: A rare Shrivastava N, Singh V,
cytomorphological diagnosi Hussain N.

2. Incidental cytodiagnosis of Santosh T, Panwar H, Bugalia Natl Med J India.

microfilaria from A, Singh VY, Hussain N 2017;30(4):241.
subcutaneous nodule
3. Diagnostic utility and pitfalls Panwar H, Joshi D, Goel G, J Cytol 2017;34:179-82.
of Tzanck smear cytology in Asati D, Majumdar K,
diagnosis of various Kapoor N
cutaneous lesions

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Institutional Human Ethics Committee

4. Cytomorphology of skin Panwar H, Goel G, Joshi D, J Cytol 2018;35:60-2

adnexal tumours: A tale of Majumdar K, Asati D,
two scalp swellings Kapoor N
5. FNAC of the Thyroid Santosh T, Panwar H, i Oncology, Gastroenterology
Following Carbimazole Kumari B, Singh VY, Arora and Hepatology Reports
Therapy in Hyperthyroidism: RD, Hussain N 2018;7(1):38-40
A Diagnostic Dilemma

6. Thoracic Endometriosis Viswanath V, Khurana A, Sultan Qaboos Univ Med J.

Presenting with Bilateral Goyal A, Niwariya Y, Singh 2018 May;18(2)
Hydropneumothorax.Sultan MP, Panwar H, Goel G
Qaboos Univ Med J.
2018;18:e245-e246.

7. Tubercular mastitis Das A, Panwar H, Hussain Indian J Med Paediatr Oncol

masquerading as carcinoma N. 2018;39:516-8
breast in elderly female: A
diagnostic dilemma
8. A clinicopathological study Panwar H, KhuranaU, Gupta Indian journal of Obstetrics
of neoplastic and K, Shrivastava S, Jain A, and Gynaecology Research
preneoplastic lesions of Sankhala K 2016;3(4):400-406
cervix along with HPV
genotyping in biopsy proven
preneoplastic lesions
9. Loose bodies in right elbow Hemlata Panwar, V Senthil Journal of Emergencies,
joint: Post traumatic? or post Kumar, Vivek Trikha, Trauma, and Shock (J Emerg
infective? Arulselvi Subramanian Trauma Shock)2013 | April-
June | Volume6 | Issue2

Dr Sheetal Rathi

Senior Resident, Department of Pathology and lab medicine

Email Id. rathi.1988@gmail.com

Publications:
1) Jindal R, Jain P, Joseph M, Krishnan S, Malpani S, Yadav J, Kaur K. Idiopathic calcinosis cutis of
the medial canthus of eye: A case report. European journal of pharmaceutical and medical
research.2017; 4 :478-480
2) Jindal R, Krishnan S, Jain P, Malpani S, Joseph M. Endometrial stromal sarcoma masquerading
as uterine fibroid. Sch J Med Case Rep 2017; 5:17-19

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Dr Garima Goel

Associate Professor, Department of Pathology and Lab Medicine

Email.Id. garima.atho@aiimsbhopal.edu.in

Publications:

Research Papers, Reports: 25

Important recent publications:

1. Awasthi P, Goel G, Khurana U, Joshi D, Majumdar K, Kapoor N. Reproducibility of

‘The Bethesda System for reporting Thyroid Cytopathology’: A Retrospective
Analysis. J Cytol 2018;35:33-6

2. Panwar H, Joshi D, Goel G, Asati D, Majumdar K, Kapoor N. Diagnostic utility and

pitfalls of Tzanck smear cytology in diagnosis of various cutaneous lesions. J Cytol
2017;34:179-82.

3. Sharma T, Goel G, Majumdar K, Joshi D, Kapoor N. Cytomorphology of basaloid squamous

cell carcinoma: A diagnostic dilemma. Journal of Clinical and Diagnostic Research.
2017;11(4):21-22

4. Panwar H, Goel G, Joshi D, Majumdar K, Asati D, Kapoor N. Cytomorphology of skin adnexal

tumours: A tale of two scalp swellings. J Cytol 2018;35:60-2.

5. Semwal S, Joshi D, Khare A, Goel G, Kapoor N. Validation and Modification of the

Masood Scoring Index for the Diagnosis of Atypical Breast Lesions. Acta Cytol. 2017
Apr 12. doi: 10.1159/000471783. [Epub ahead of print]

6. Shrivastava A, Tadepalli K, Goel G, Gupta K, Gupta PK. Melanized fungus as an

Epidural abscess: A diagnostic and therapeutic challenge. Medical Mycology Case
Reports 2017;16:20-24.

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Institutional Human Ethics Committee

Dr Deepti Joshi, Additional Professor, Department of Pathology and Lab Medicine, AIIMS

Bhopal

Email : deepti.patho@aiimsbhopal.edu.in

Publications:

1. Joshi D, Beuhring GC. Are Viruses associated with human Breast cancer ? Scrutinizing
the molecular evidence. Breast Cancer Research and Treatment. 2012. DOI
10.1007/s10549-011-1921-4
2. D Joshi, P Singh, Y Zonunfawni, N Gangane.Metaplastic carcinoma of the breast:
cytological diagnosis and diagnostic pitfalls. Actacytological 2011; 55 (4):313-31
3. Deepti Joshi , Munira Quadari , Neha Gangane , Rajnish Joshi, Nitin Gangane.
Association of Epstein Barr Virus Infection (EBV) with Breast Cancer in Rural
Indian Women. PLoS One. 2009 Dec 4;4(12):e8180
4. Upadhye V, Majumdar A, Gomashe A, Joshi D, Gangane N, Thamke D,
Mendiratta D, Harinath BC. Inhibition of Mycobacterium tuberculosis secretory
serine protease blocks bacterial multiplicationboth in axenic culture and in
human macrophages. Scand J Infect Dis. 2009 May 27:1-8.
5. Meena M, Joshi D, Joshi R, Sridhar S, Waghdhare S, Gangane N, Kalantri SP.
Accuracy of a multispecies rapid diagnostic test kit for detection of malarial parasite
at the point of care in a low endemicity region. Trans R Soc Trop Med Hyg. 2009
Dec,103(12):1237-44.

Dr Neelkamal Kapoor,

Professor and Head, Department of Pathology and Lab Med.

Email Id: head.patho@aiimsbhopal.edu.in

Significant Professional Achievements:

1. Awarded National Academy of Medical Sciences (India) Sir Shriram

2. Memorial Award for Cancer Education 2010 (www.nams-india.in).

3. Awarded E M L Haagedoorn Prize and Keynote address 2009 at International

Cancer Education Conference held at Houston Texas USA. First Indian to be awarded
this prestigious honor (www.eaceonline.com).

4. FAIMER (Federation for Advancement of InternationalMedical Education &

Research, USA (www.faimer.org) Fellowship. First Medical teacher to be selected

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Institutional Human Ethics Committee

for this prestigious fellowship in Madhya Pradesh.

5. Fellow Indian College of Pathologist.

Recent Publications:

Books

1. Member of Indian Advisory Board of “Robbins Pathologic Basis of Disease”

South East Asia edition.

2. Contributor to “Cancer incidence in five continents” Vol X (IARC) as PI PBCR

Bhopal.

3. Authored "Practical Manual of Pathology" Publishedby SR Publishers New

Delhi. ISBN No. 978-81-8191-223-7.

Recent publications in Indexed Peer Reviewed Journals

No of Name of the Indexed/N Year of Impa Citations

publicatio journal on Indexed publicati ct
ns on factor

1 Indian J Indexed 2018 0.75 Semwal S, Joshi D, Goel G,

Dermatol. Asati D, Kapoor N.
Clinico-Histological
Correlation in Hansen's
Disease: Three-year
Experience at a Newly
Established Tertiary Care
Center in Central India.
2018 Nov-Dec;63(6):465-
468.

Citations: Nil

2 J Parasit Dis Indexed 2018 0.36 Khurana U, Majumdar K,

Kapoor N, Joshi D, Goel
G, Sharma T, Biswas D.
Spectrum of parasitic
infections in centrifuged
urine sediments from a
newly developed tertiary
care centre in Central India.

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2018 Dec;42(4):608-615

Citations: Nil

3 Breast J. Indexed 2018 2.424 Semwal S, Rai R, Joshi,D,

Asati D, Goel G, Kapoor
N. Cutaneous metastases
from carcinoma breast
presenting as vesiculo-
bullous lesion. 2018
Jul;24(4):660-661

Citations: Nil

4 J Cytol Indexed 2018 0.68 Awasthi P, Goel G,Khurana

U, Joshi D, Majumdar K,
Kapoor N Reproducibility
of ‘The Bethesda System
for reporting Thyroid
Cytopathology’: A
Retrospective
Analysis2018;35:33-6

Citations: Nil

5 J Cytol Indexed 2018 0.68 Semwal S, Joshi D, Goel G,

Mittal N, Majumdar K,
Kapoor N . Cytological
diagnosis of Erythema
Nodosum Leprosum in
clinically unsuspected
cases- A report of two
cases2018;35:63-5

Citations: Nil

6 J Cytol Indexed 2018 0.68 Panwar H, Goel G, Joshi D,

Majumdar K, Asati D,
Kapoor N.
Cytomorphology of skin
adnexal tumours: A tale of
two scalp swellings. J
Cytol2018;35:60-2

PMCID:PMC5795733

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 All India Institute of Medical Sciences Bhopal
Institutional Human Ethics Committee

Citations: 01

7 Med Sci Law Indexed 2018 0.51 Sangita C, Garima G,

Jayanthi Y, Arneet A,
Neelkamal K. Histological
indicators of cutaneous
lesions caused by
electrocution, flame burn
and impact abrasion.Med
Sci Law. 2018
Oct;58(4):216-221.

Citations : Nil

8 J Cytol Indexed 2017 0.68 Panwar H, Joshi D, Goel G,

Asati D, Majumdar K,
Kapoor N.Diagnostic
utility and pitfalls
of Tzanck smear cytology
in diagnosis of various
cutaneous lesions J Cytol
2017;34:179-82.

Citations: 02

9 Acta Cytol Indexed 2017 1.16 SemwalS, Joshi D, Goel G,

Khare A, Kapoor N.
Validation of Masood
scoring index for
assessment of atypical
breast
lesionsActaCytologica
2017;61:111-116

Citations: Nil

10 JCDR Indexed 2017 0.35 Sharma T, Goel G,

Majumdar K, Joshi D,
Kapoor N.
Cytomorphology of
basaloid squamous cell
carcinoma: A diagnostic
dilemma Journal of Clinical
and Diagnostic Research.
2017;11(4):21-22

21
 All India Institute of Medical Sciences Bhopal
Institutional Human Ethics Committee

Citations: Nil

11 J Cancer Res Indexed 2017 0.842 Majumdar K, Khurana U,

Ther Asati D, Goel G, Joshi D,
Kapoor
N.Multinodularfibroepitheli
oma of Pinkus with an
isolated focus of evolving
basal cell carcinoma in
chronic lymphedematous
lower limbJ Cancer Res
Ther. 2017;13(6):1038-
1041

PMID: 29237972

Citations: Nil

12 DiagnCytopat Indexed 2016 1.014 Khare A, Joshi D,

hol Majumdar K, Gupta V,
Goel G, Kapoor N
Cytological findings of
odontogenicmyxofibroma:
A diagnostic dilemmaDiagn
Cytopathol.
2016;44(4):329-33.

PMID:26801006

Citations: 01

13 Blood Res Indexed 2016 0.94 Khurana U, Joshi D,

Sharma T, Santoshi J,
Kapoor NOligosecretory
multiple myeloma: a case
report. Blood Res. 2016;
51(1): 63–65.

PMCID: PMC4828533

Citations: 05

14 Diagn Indexed 2016 1.014 KhareA,JoshiD,Majumdar

Cytopathol. K, Goel G, Kapoor N.
Negative shadows
conveying a positive note
Diagn Cytopathol.

22
All India Institute of Medical Sciences Bhopal
Institutional Human Ethics Committee

2016;44(5):410-2

PMID: 26879040

Citations: Nil

23