Name of Patient Anding, Jessica Donaire Age 5 yrs. 5 months Height 105.

5 cm
Diagnosis R/O conjunctivitis secondary Sex Female Weight 17 kg
to trauma
Doctor Dr. Tipgos Date of Admission Not yet admitted Body Build sthenic

Drug Data Classification Mechanism of Action Indication Contraindications Adverse Reaction Nursing Responsibilities
 Generic Name Therapeutic:  Pharmacokinetics  General Hypersensitivity CNS: Agitation,  Before
Antibiotic A Indications to amoxicillin or anxiety, behavior • Patients with
amoxicillin trihydrate Well absorbed from To treat ear, nose, its com- changes, mononucleosis
(amoxycillin) Pharmacologic duodenum (75–90%). throat, GU tract, ponents confusion, shouldn’t
aminopenicillins More resistant to acid skin,  Precaution dizziness, receive amoxicillin
Trade Name inactivation than and soft-tissue Severe renal insomnia, because this class of
Amoxil, Apo-Amoxi other penicillins infections caused insufficiency (↓ reversible drugs may cause an
(CAN), DisperMox, D by sus- dose if CCr <30 hyperactivity, erythematous rash.
Moxatag, Novamoxin Diffuses readily into ceptible gram- mL/min) seizures • Use drug cautiously in
(CAN), Nu-Amoxi most body tissues and positive and CV: patients with hepatic
(CAN), Polymox, fluids. CSF gram- • Infectious Hypersensitivity impairment.
Trimox, Wymox penetration increased mononucleosis, vasculitis • Monitor hepatic and
negative acute
when meninges are organisms, To EENT: Black, renal function and CBC,
 Patients Dose inflamed. Crosses lymphocytic hairy tongue; as ordered, in patients
treat tonsillitis leukemia, or
Suspension for 7 days placenta; enters breast mucocutaneous on prolonged therapy.
or pharyngitis cytomegaloviru
 Minimum Dose milk in small amounts caused by
candididasis; • use cautiously in breast-
Children age 12 s infection (↑ tooth feeding and elderly
Streptococcus risk of rash)
wk and over M&E pyogenes, To discoloration patients.
weighing less than 70% excreted treat lower • OB: Lactation: GI: Diarrhea, • Expect to start therapy
20 kg. 20 mg/kg unchanged in the respiratory Has been used diarrhea related to before culture and
daily in divided urine; 30% safely Clostridium sensitivity test results
tract infec
doses every 8 hr metabolized by the difficile, elevated are known.
tions caused
 Maximum Dose liver by susceptible  Drug interaction
liver enzymes, as ordered.
500 mg every 8 hr gram-positive hemorrhag- ic or PATIENT TEACHING
-drug to drug
or 875 mg every  Onset and gram- allopurinol:
pseudomembrano • Tell patient to refrigerate
12 hr Unknown us colitis, reconstituted sus-
negative Increased risk of
 Availability and Peak jaundice, hepatic pension and to shake
organisms, rash
color Unknown dysfunction, well before each use.
 CAPSULES,  Duration\ Treatment of chloramphenicol, nausea, vomiting • When amoxicillin
CHEWABLE 6–8 hr » Skin and skin erythromycins, GU: Crystalluria, suspension is prescribed
TABLETS, ORAL  Drug Half Life structure sulfon- amides, vaginal mycosis for a child, instruct
SUSPENSION, Neonates: 3.7 hr; infections tetracyclines: HEME: parents to place it
PEDIATRIC Infants and Children: Reduced Agranulocytosis, directly on child’s
DROPS, POWDER 1–2 hr; Adults: 0.7– bactericidal effect anemia (including tongue to swallow. If
OR  Patients of amoxicillin hemolytic this doesn’t work, tell
1.4 hr
TABLETS FOR Actual methotrexate: anemia), parents to mix dose of
ORAL Indication Increased risk of eosinophilia, suspension with formula
SUSPENSION, Treatment of methotrex- ate granulo- cytosis, or cold drink (milk, fruit
TABLETS » Skin and skin toxicity leukopenia, juice, ginger ale, water)
 Routes of structure oral contraceptives thrombocytopenia and have child drink it
administration infections with estrogen: , immediately.
P.O. Possibly thrombocytopenic • Instruct patient using
76 purpura DisperMox tablets to
amphetamine SKIN: Erythema place one tablet and
sulfate multiforme, about 2 teaspoonfuls of
erythematous water in a glass, drink
reduced maculopapular entire mix ture, add
effectiveness of rash, generalized more water to the glass,
contraceptive exanthe- matous and drink again to
probenecid: pustulosis, ensure delivery of full
Increased Stevens-Johnson dose.
amoxicillin effects syn- drome, toxic During
epidermal • Be aware that chewable
necrolysis, tablets and tablets for
urticaria Other: oral suspension contain
Allergic reaction, phenylalanine.
anaphylaxis, • Tell patient to chew or
serum crush chewable tablets
sicknesslike and not to swallow them
reaction (such as whole.
arthralgia, • Don’t confuse
arthritis, fever, amoxicillin tablets with
myalgia, rash, and amoxicillin tablets for
urticaria) oral suspension
(DisperMox). They’re
not interchangeable.
• If allergic reaction
occurs, stop
amoxicillin immediately
and provide emergency
care as indicated and
ordered.
• Monitor patient for
superinfection. If it
occurs, expect to
discontinue drug and
provide treatment

After
• Teach patient to report
adverse reactions
• notify prescriber if
infection worsens or
doesn’t improve after 72
hours.
• To prevent infection
from recurring, urge
patient to take
amoxicillin for full
length of time
prescribed, even if he
feels better.
• Urge patient to tell
prescriber about diar-
rhea that’s severe or
lasts longer than
3 days. Remind patient
that watery or bloody
 stools can occur 2 or
more months after
antibiotic therapy and
may be serious,
requiring prompt
treatment.
• Monitor patient closely
for diarrhea, which may
indicate
pseudomembranous
colitis
• Expect treatment that
lasts at least 10 days for
hemolytic streptococci
infections.

Source: Source: Source: Source: Source: Source: Source:

Deglin, Deglin, http://www.drugguide Deglin, Deglin, http://www.drugg Deglin,
Vallerand, Sanoski, D Vallerand, Sanos .com/ddo/ub/view/Da Vallerand, Sanos Vallerand, Sanosk uide.com/ddo/ub/ Vallerand, Sanoski, Davis’
avis’s Drug Guide for ki, Davis’s Drug vis-Drug- ki, Davis’s Drug i, Davis’s Drug view/Davis-Drug- s Drug Guide for Nurses
Nurses F.A. Davis Guide for Nurses Guide/51047/3/amoxi Guide for Nurses Guide for Nurses Guide/51047/4/a F.A. Davis Company.
Company. 2010 F.A. Davis cillin?q=amoxicillin F.A. Davis F.A. Davis moxicillin?q=amo 2010
Company. 2010 Company. 2010 Company. 2010 xicillin