FCPS Part-I Model Test 3 Paper: 3, Exam: Model Test 10, A sexually active 24-year-old woman complains of vaginal itching and a malodorous purulent vaginal discharge. To verify your tentative diagnosis of trichomoniasis, you should include which of the following in your workup? Specific serologic test (Ova and parasite fecal smear ‘Wet mount of vaginal fluid Enzyme-linked immunoassay (ELISA) test of serum E. Stool culture pnw 11, Which of the following substances most likely has the greatest affinity for neutrophils? A. Ca B. Fucosyl transferase C. p2ntegrin D. P-selectin E, TNFa 12, A 25-year-old man has a lifelong hemorrhagic diathesis. The PT and bleeding time are normal, but the APTT is prolonged. The most likely cause of the Dleeding disorder is a platelet fimctional disorder. factor VII deficiency. factor VIII deficiency. factor IX deficiency von Willebrand disease. rPonp> 13, A 56-year-old diabetic woman has recently been. treated with a 2-week course of antibiotics for a skin infection. She returns to the clinic for follow-up with a new complaint of a “cottage cheese-like” vaginal discharge with significant vaginal itching. The most likely cause of these symptoms is A. C. granulomatis B. albicans. CC. chaneroid. D. herpes simplex. E. Neisseria meningitidis MCQ: 1-35, SBA: 36-50, Total time: Lhour 40 min 14, A 68-year-old postmenopausal woman presents for evaluation of the recent onset of vaginal bleeding, and a diagnosis of type I endometrial carcinoma is made on endometrial biopsy. Which of the following is a risk factor for this condition? A. Endometriosis B. Multiparity CC. Salpingitis D. Early sexual activity with multiple partners E, Obesity 15. A 5-year-old gitl begins developing secondary sextal characteristics, including pubic hair growth and breast development. Her concerned parents bring her to the pediatrician for evaluation. An abdominal ultrasound examination reveals an ovarian mass. The mass is resected, and pathologic examination reveals it to be a granulosa cell tumor. Which of the following histologic findings is a characteristic of this type of ovarian tumor? Signet-ring cells Call-Exner bodies Schiller-Duval bodies Hyperfunctioning thyroid tissue ‘Transitional cell epithelium moopeFCPS Part-I Model Test 3 Paper: 3, Exam: Model Test MCQ: 1-35, SBA: 36-50, Total time: Lhour 40 min SBA 6.4 10-year-old child has a primary pulmonary Mycobacterium tuberculosis infection. Which of the 1. Within minutes of a bee sting, a 23-year-old woman following features of tuberculosis is most comect? develops generalized pruritus and hyperemia of the skin, followed shortly by swelling of the face and eyelids, ‘dyspnea, and laryngeal edema. This reaction is mediated by- antigen-antibody complexes. cytotoxic T cells IgA antibodies. IgE antibodies. IgG antibodies. roow> 2. HLA B27 associated disease — Multiple sclerosis, Gonococcal urethritis Gonococeal uveitis, Sjogren's syndrome RA roap> 3 .Wrong information about serum sickness — A. can be caused by injection of Diphtheria antitoxin. B. is common following imnmnization against tetanus. C. can follow au injection of penicillin D. is mediated by immune complexes. may involve IgE. ft 4. Long-term carriage and shedding is most likely to occur after gastrointestinal infection with which of the following species? A. Escherichia coli 0157:H7 B. Shigella dysenteriae C. Vibrio cholerae D. Campylobacter jejuni E. Salmonella typhi 5. All of the following are virulence factors associated ‘with N gonorthoeae except Pa, Por Lipooligostecharide (Opa proteins A thick polysaccharide capsule ryose A. In primary tuberculosis, an active exudative lesion develops and rapidly spreads to lymphatics and regional lymph nodes. B. The exudative lesion of primary tuberculosis often heals slowly. C. Iftuberculosis develops years later, it isa result of another exposure to M tuberculosis D. Inprimary tuberculosis, all of the infecting M ‘tuberculosis organisms are killed by the patient’s. immune response. E, Inprimary tuberculosis, the immune system is primed, but the PPD skin test result remains negative until there is a second exposure to M tuberculosis. 7. Which one of the following groups of antimicrobial agents acts on microorganisms by inhibiting protein synthesis? Fluoroquinotones Amiinoglycosides Penicillins Glycopeptides (eg. vancomycin) Polymyxins moap> 8. A. 36-year-old nurse is found to be both HBsAg positive and HBeAg positive. The nurse most likely ‘Has acute hepatitis and is infectious Has both HBV and HEV infections Has a clonic HBV infection Has cleared a past HBV infection ‘Was previously immunized with HBV vaccine prepared from healthy HBsAg-positive carriers moab> 9. Human papillomavirus can cause cancer in humans and is most commonty associated with A. Rectal polyps Breast cancer Prostate cancer Anogenital cancers, Mesothetiomas moo30. FCPS Part-I Model Test 3 Paper: 3, Exam: Model Test MCQ: 1-35, SBA: 36-50, Total time: hour 40 min cIN- > Arises most commonly at squamocolumnar junction Has a peak incidence of 50-55 years Becomes invasive in 70-80% cases Involves mucous glands of endocervix Is predominantly squamous in type moo Genital TB — A. Most commonly affects the fallopian tubes, B. Is sexually transmitted C. May cause ascites D. Causes infertility E, Mode of spread is ascending Risk of developing pre-eclampsia increases with — Increased maternal age High parity H mole ‘Maternal cardiac disease DM rPonw> Lactose fermenters — E.coli ‘Salmonella Klebsiella Proteus Enterobacter rPonw> ). Microorganisms passing through breast milk — Staph, aureus cu HILV an HBV moow> About endotoxin — Polypeptide Gene located at bacterial chromosome Heat labile Poorly antigenic Secreted fiom cell room 31 32 Toxin of streptococcus ~ Exythrogenic toxin Enterotoxin Leukocidin Exotoxin B Streptolysin mone DNA enveloped virus ~ A. HSV B. EBV C. Adeno virus D. HPV E. Pox virus 33. About Toxoplasma — 34 Only cystic form is present Infection provides cell mediated immunity Definitive host is human ‘Congenital infection occurs only when mother is infected during pregnancy ‘Trophozoites crosses placenta yopp nm Comrect pairs — ‘Campylobactor—GBS Shigella — Reiter's syndrome ‘Yersinia — Lyme arthritis Hepatitis C virus —Multiple sclerosis CMY —Cryoglobutinemia monwp - Example of type II hypersensitivity reaction — Farmer's lung AGN Rheumatoid arthitis Syphilis Malaria moope13 14. 15 16. 17. 18 FCPS Part-I Model Test 3 Paper: 3, Exam: Model Test MCQ: 1-35, SBA: 36-50, Total time: Lhour 40 min Benign tumors having no capsule — Hemangioma Leiomyoma Papilloma Polyp Lipoma rone> ‘Stein Leventhal syndrome — Oligomenorthoea Increased level of FSH Low level of LH Persistant ovulation Absent corpora lutea room ‘Normal resistance of vagina — Apposing two wall ‘Stratified squamous epithelia Acidic pH Gram positive anaerobie bacteria Secretion of apocrine gland rPonw> Parabasal cell found during ~ Childhood Pregnancy Post partum period (Oral pill users Menopause roop> Dermatomyositis is a paraneoplastic syndrome of — A. Bronchogenie carcinoma B. Thymoma C. Breast carcinoma D. Pancreatic carcinoma E, Gastric carcinoma ‘The metabolic response to injury — ‘The main source of energy is liver glycogen. Potassium excretion in urine is increased. ‘There is an increase in insulin secretion. ‘The specific gravity of the urine is increased, Liver glycogen is mobilized. rPonp> 19. Haemolytic disease of the newborn ~ 23 24 A moape Itis reduced if there is parental ABO incompatibility. Factor ILVIL, IX and X are vitamin K~ dependent Platelet counts are reduced. Could be due to anti-Lewis antibodies. The direct Coombs’ test detects the presence of free immunoglobulin in serum. ). Risk factors for fibroid — ‘Multiparity Smoking Obesity Black woman Hyperestrogenic state HPV with high oncogenic risk — 16 18 31 33 u Specific tests for diagnosis of Syphilis — monw> FTA —abs VDRL ‘TPHA EIA (enzyme immmne assay) ‘TPI (Treponema pallidum immobilization) About bacterial vaginosis — . Greenish yellow vaginal discharge moo Thick vaginal discharge pH A imeversible process May be caused by chronic irritation May be caused due to vitamin A deficiency Always occurs in epithelial tissue Precancerous condition 2. Causes of metastatic calcification — rPonwP Neoplasm of parathyroid ‘Vitamin D intoxication Multiple myeloma Sarcoidosis Renal tubular acidosis 3. Regarding hyperplasia — A B. c. D. E. Increased mumber of cell division Occurs in labile cell only ‘Nature of stinmuli is hormonal or growth factors Growth occurs in the G2 phase Physiologic hyperplasia isa fertile soil for ‘malignant transformation 4, Antioxidants — rPonw> Vitamin E Ceruloplasmin ‘Serum albumin Cysteine Lactoferrin 5. Comect pair — 6 monee Emenee ‘Vasoconstriction —LT C4 Vasodilatation—TXA2 Increased vascular permeability - LT E4 Leucocyte adhesion — HETE ‘Vasoconstriction — PGI2 sic infarct found in — Heart Intestine Kidney Spleen Brain 7. Extrinsic causes of cardiogenic shock — Cardiac temponade Pulmonary embolism MI Amhythmias Rupture of heart mone 8. Secondary Amyloidosis — Rheumatic fever Tuberculoid leprosy Bronchiectasis, Heroin abuse Non Hodgkin’s lymphoma Poop 9. Primary immune deficiency due to T cell deficiency- 10. Chronic Gramulomatous disease Hereditary angioedema Wishkott Aldrich syndrome Hyper TeE syndrome ‘Thymic aplasia ronwP Sex cord stromal tumor of ovary — Fibroma —Thecoma Sertoli cell tumor ‘Theca cell tumor Granulosa cell tumor Androblastoma rmoop> - About complete mole — Karyotype is triploid Some villi are edematous Cellular atypia is absent Seruim hCG is less elevated (Chance of transforming into choriocarcinoma is rare than partial mole monwp . Structure of hemoglobin — Hb A : 0262 Hb F: 022 Hb Barts : 74 Hb Gower 2 : a2e2 Hb A2: 282 moappEFFIT 10.1 1LFFFEF wFIFIT 13.TTFFF .4FTFIT 1SFFTET 16.TTFTT AVIFTET 18.TTTFF Ou Bmows