Superior Technology Over Traditional Analyzers

Critical Care

Immediate Care Diagnostics

 Superior Technology Over Traditional Analyzers

pH, PCO2, PO2

Ca++, Na+, K+

Glucose, Lactate

Hct

CO-Oximetry *

PT, APTT, ACT, ACT-LR **

Superior Technology
GEM Premier 3000 features state-of-the-art technologies in biosensors,
cartridges, quality control and information management to deliver a system
of unrivaled simplicity, reliability and analytical performance.
Only GEM Premier 3000 offers:
• Patented planar biosensors for pH, gases, electrolytes, hematocrit, glucose and lactate
• Unique single disposable, multi-use cartridge technology
• iQMTM, a proprietary, revolutionary, automatic quality assurance system
• GEMwebTM, an innovative remote management system

* With the optional

GEM OPLTM or IL 682 CO-Oximeter module
** With the optional
GEM PCLTM coagulation module
 Comparison with Traditional Analyzers

Patented State-of-the-art Sensor Comparison Traditional Analyzers GEM Premier 3000

Planar Biosensors
Measurement • Traditional • Planar biosensors
▲ GEM Premier 3000 incorporates Technology electrodes
advanced maintenance-free biosensors
laid in a solid-state card Maintenance • Routine replacement • None
▲ Requirements of electrodes
In contrast, traditional analyzers are • Routine changing of caps
based on technologies developed or membranes
• Running of cleaning and
nearly 50 years ago deproteinizing solutions

Maintenance Traditional Analyzers GEM Premier 3000

Comparison

Typical Consumables • Gas Tanks • One disposable PAK

• Electrodes • Printer paper
• Electrode caps or membranes
Exclusive Multi-use, Single-component, • Flush solutions
Maintenance-free Cartridge Technology • Calibrants
• Cleaning solutions
▲ Only GEM Premier 3000 offers a single • Waste container
component, multi-use PAK that includes • Conditioners
everything you need: sensors, solutions, • Deproteinizers
• Pump tubing
gases, tubing, waste bag and even the • Sampler
sampler. Just replace the cartridge once • Printer paper
every three weeks
▲ Maintenance • Replace gas tanks • Replace printer paper
Traditional systems require dozens of requirements • Replace electrodes
consumables and labor consuming • Replace electrode caps
maintenance tasks or membranes
• Clean sampler
• Replace solutions
• Decontaminate empty
waste container
• Replace tubing
• Deproteinize electrodes
• Clean electrodes and
sample path
• Replace printer paper

Labor requirements • Hours every week • None

for upkeep • Complex training
• Downtime for
troubleshooting
Comparison with Traditional Analyzers

GEM Premier 3000 Correlation 1 CV 2

Analyte r Reference Low Control High Control
pH 0.992 IL 1745 0.006 SD 0.010 SD
PCO2 0.992 IL 1745 3.6% 2.3%
PO2 0.998 IL 1745 1.5% 2.6%
Na+ 0.953 IL 1745 1.1% 0.9%
K+
0.968 IL 1745 1.6% 1.0%
Excellent Analytical Performance Ca ++
0.955 IL 1745 2.2% 1.8%
Glucose 0.997 VITROS® 3.4% 2.6%
▲ GEM Premier 3000 delivers analytical
Lactate 0.992 VITROS ®
3.9% 3.0%
results as good as the best traditional
systems. Hct 0.979 IL 1745 1.1% 1.5%

GEM Premier 3000 delivers first-rate analytical performance.

1 Correlation of GEM Premier 3000 versus reference analyzers.
Cost-effectiveness 2 Coefficient of Variation of controls over 20 cartridges during 3-week use life (total of 450 samples per level).

▲ The cost of the GEM Premier 3000 is

comparable to traditional analyzers, GEM Premier 3000 offers
significant labor savings
while delivering significant labor savings. and guarantees confidence
▲ The single cartridge greatly facilitates in the annual operational cost.
(1) Data on file, IL
inventory management, budgeting and
assures that there are no hidden or
unplanned material costs.
▲
Traditional systems require scarce
skilled labor for routine maintenance
and troubleshooting. Budgeting and
inventory management can be complex
when expensive, unplanned, component
replacement is necessary.

Quality Control Breakthrough: iQM TM

▲ Only GEM Premier 3000 incorporates
the new and revolutionary Intelligent
Quality Management (iQM) system. QC Comparison Traditional Analyzers GEM Premier 3000
iQM is an active total process control Method • Traditional QC ampoules • iQM
system that automatically, and without
human intervention, manages the Automation • External mechanical • Completely integrated
quality of the system. iQM’s real-time, ampoule breakers in PAK
propietary Pattern Recognition software Process • Passive, discrete process, • Active, real-time and
automatically detects errors identifies controlling quality typically continuous process control
micro-clots and interferences, takes every 8 hours
corrective action and documents the Automatic • No • Automated corrective
event. Corrective action action and documentation
▲ implemented without
Traditional analyzers require external
human intervention
QC solutions run at discrete intervals.
A skilled operator must choose to
implement the appropriate corrective
action when traditional QC fails.
 Comparison with Traditional Analyzers

Remote System Management: GEMwebTM

▲ Only GEM Premier 3000 offers GEMweb,
an innovative remote management
system that turns the GEM Premier 3000
into a website accessible by any
authorized user from any network
computer. Among other operations,
GEMweb allows remote control of
decentralized analyzers with remote
review of QC and patient data.

GEMweb allows remote management from any network computer.

Standardized Platform, Cartridge size, Blood Gas Blood Gas Blood Gas On-Board
Customized Cartridges Analyte menu and Hematocrit Electrolytes Electrolytes Use-Life
Use-life Hematocrit Metabolites
▲ Only GEM Premier 3000 offers true Hematocrit
standardization: one single platform 75-Test ✔ ✔ -- 3 weeks
for whole blood testing throughout the 150-Test ✔ ✔ ✔ 3 weeks
hospital: laboratory, respiratory and 300-Test ✔ ✔ ✔ 3 weeks
point-of-care. Using identical systems
450-Test ✔ ✔ ✔ 3 weeks
in all settings helps assure correlation
and standardizes procedures, training 600-Test -- ✔ ✔ 2 weeks
inventory management and overall GEM Premier 3000 cartridges allow customization of the system to the needs of any location.
supervision, assuring support of remote And if needs change, it is as easy as inserting a different cartridge.

locations.
▲ 13 different cartridge options allow
the GEM Premier 3000 to meet the
demands of every testing location, both
high and low volume, centralized and
decentralized.
 GEM OPL™
Superior Technology Over Traditional Analyzers CO-Oximetry
tHb, O2Hb, COHb, MetHb,
RHb, SO2m

IL 682
CO-Oximetry
tHb, O2Hb, COHb, MetHb,
RHb, SO2m
System Comparison Traditional Analyzers GEM Premier 3000

Core technologies • Traditional electrodes • Planar biosensors

• Single disposable, GEM PCL™
• Dozens of consumables
multi-use cartridge Coagulation
PT, APTT, ACT, ACT-LR
Maintenance • Extensive • None
• Labor-consuming
IMPACT™ for Critical Care
Analytical performance • Excellent • Excellent
Information Management
Quality control • Traditional ampoules • iQM, automated active EDI or Terminal Emulation
run at discrete intervals process control Option
• Manual corrective action • Automated corrective
action and documentation

Remote Management • No • Yes

via GEMweb IL Synthesis™

Total hospital • No • Yes ABG, ISE, CO-Ox,

standardization Hct, Glucose,

GEM is a registered trademark and GEMweb, IMPACT, OPL, PCL, Premier and Synthesis are trademarks of Instrumentation Laboratory.
Lactate, Bilirubin

Worldwide Locations US, Canada, Latin America

Headquarters
Pacific Headquarters
Minato-ku, Tokyo, Japan
Europe, Middle East,
Africa Headquarters
France
Paris
Lithuania
Kaunas
Lexington, MA, U.S.A. Tel. 81-3-3437-6350 Milano, Italy Tel. 33-1-53338600 Tel. 370-37-313157
Instrumentation Laboratory Tel. 1-781-861-0710 Tel. 39-02-25221
Hong Kong Germany Poland
Corporate Headquarters Mexico Hong Kong Austria Kirchheim bei München Warszawa
Barcelona, Spain Colonia Juarez Tel. 852-27927773 Wien Tel. 49-89-909070 Tel. 48-22-3361800
Tel. 34-93-4010101 Tel. 52-5-525-8639 Tel. 43-1-2565800-0
Japan Hungary The Netherlands
USA Minato-ku, Tokyo Belgium Budapest Breda
All rights reserved - Printed in Italy - Grafica Briantea - 12/02

Lexington, MA Tel. 81-3-3437-6350 Zaventem Tel. 36-1-4527810 Tel. 31-76-5480100

Tel. 1-781-861-0710 Tel. 32-2-7252052
Italy United Kingdom
Czech Milano Warrington, Cheshire
Praha Tel. 39-02-25221 Tel. 44-1925-81-0141
Tel. 420-2-7816047

Instrumentation Laboratory on the Internet: www.ilww.com

This Brochure is used throughout the world. Applications / tests listed may not yet be approved by the regulatory authorities in your country.
p/n 98087-60 EU - Rev. 0

Please contact the appropriate office above for specific information regarding availability in your country.
IL product specifications are subject to modification to assure the highest quality performance.
Some of the IL sites may still be in the process of completing ISO.

A CH Werfen Company