1.

Which of the following is an orally disintegrating tablet formulation of prednisolone, used to treat exacerbations of asthma and other
inflammatory diseases and conditions in children?

a. Celestone Soluspan
b. PediaPred
c. Orapred
d. Vasocidin
e. Juvéderm
View Answer

1(c). Orapred ODT (Prednisolone sodium phosphate disintegrating tablets) is a sodium salt of the phosphoester of the glucocorticoid prednisolone. It is indicated in the treatment of the
atopic dermatitis, Crohn's disease, ulcerative colitis and acute exacerbations of chronic obstructive pulmonary disease (COPD).

Dosage of Orapred ODT should be individualized according to the severity of the disease and the response of the patient.

The initial dose of Orapred ODT may vary from 10 to 60 mg (prednisolone base) per day, depending on the specific disease entity being treated.

Fluid retention, alteration in glucose tolerance, elevation in blood pressure, behavioral and mood changes, increased appetite and weight gain are commonly reported side effects of
Orapred.