Professional Documents
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in Affective Disorders
Nancy J. C. Andreasen, MD, PhD, Bruce Pfohl
\s=b\ Various aspects of speech and language were compared, these investigations are of two types: those that attempt to
using psycholinguistic techniques, in a group of 15 depressed examine formal elements of speech and writing such as
patients and 16 manic patients: lexical diversity, syntactical grammar and syntax, and those that attempt to examine
complexity, syntactical elements, and content analysis. Contrary aspects of content such as vocabulary word choice.
to anticipation, the manic patients did not show more varied
word choice or complexity of sentence structure than the depres- Analyses of form have grown increasingly sophisticated.
sives. In particular, they did not differ significantly in type-token
Newman and Mather1 made an early effort to examine
ratio. The greatest difference was in syntactical elements, with speech in patients suffering from mania or depression by
manics using more action verbs, adjectives, and concrete nouns, studying such variables as pitch, tempo, syntax, and
while the depressed patients used more state of being verbs, latency of response. Their results are largely descriptive,
modifying adverbs, first-person pronouns, and personal however, and provide no quantitative data. Lorenz and
pronouns. When compared by content analysis, the manics used Cobb have compared the speech of manies to that of
more words reflecting a concern with power and achievement. normals by using more rigorous quantitative methods such
These results imply that depressive speech tends to be more as determining the distributions of parts of speech or the
vague and qualified and to show considerable self-preoccupa- number of words spoken per minute.- Manies were found to
tion, while manic speech tends to be colorful and concrete and to have significantly different speech patterns. Lorenz and
show more concern with things than with people.
Cobb have also examined speech in neurotic patients.'·'
(Arch Gen Psychiatry 33:1361-1367, 1976) Determination of the verb-adjective (V-A) ratio was
developed in an effort to find a quantitative method of
patients' relating grammatical forms to psychopathology. Originally
Psychiatrists thought,
content of
frequently speak
disorder. Too often we
forget
stream of
about their
thought, or thought
that our only way of learning
developed by Busemann,'' it was considered to be an "action
quotient" or an index of emotional instability. Although
about a patient's thoughts is through his speech and the measure was developed for use in children, a variety of
language, either spoken or written. Spoken or written investigators have applied it to psychiatric patients. Fair¬
language may not be an accurate or reliable index of banks" and Mann7 have found schizophrenics to have a
thought, even when it is supposed to approximate it closely higher V-A quotient than normals, while Lorenz and Cobb-
as in free association, but is the only index we have have found manies and hysterics to have a higher quotient
available. Given this fact, it is something of an oddity that than normals. Benton et al8 obtained a higher quotient in
so much has been written by psychologists and psychia¬ people with high anxiety as compared to low anxiety, while
trists about thought and so little about language. Balken and Masserman" found anxiety states to have a
Linguistics is a relatively new field, of course, and higher quotient in comparison with conversion hysterics.
psycholinguistics is even newer. Nevertheless, a number of Very few studies have been able to replicate the actual
investigators have attempted to apply linguistic figures of the others, however; for example, the quotient in
techniques to a variety of psychiatric disorders. Basically, normals has been variously reported as 1.07, 1.98, and 3.43.
Such variability is probably due to differences in definition
of terms and in sample collection.
Accepted for publication Dec 19, 1975.
From the Department of Psychiatry, University of Iowa College of Spreen and Wachal have attempted to refine methodol¬
Medicine, Iowa City. ogy in syntactical analysis still further by describing a
Reprint requests to Department of Psychiatry, University of Iowa
Hospitals and Clinic, 500 Newton Rd, Iowa City, IA 52242 (Dr precise method of collecting and transcribing speech
Andreasen). samples and developing sophisticated statistical methods
suffering from a wide range of psychiatric disorders: prominent part of the illness and relatively persistent, although it
delusional behavior, impulsive behavior, compulsive behav¬ may alternate with depressive mood. If the manic symptom only
occurs during periods of alcohol or drug intake or withdrawal from
ior, and depression. Gottschalk and associates--"1 have
attempted to examine interpersonal and emotional aspects them, it should not be considered here.
B. If mood is elevated, at least three of the following symptom
of content by developing an elaborate weighted scoring
categories must be definitely present to a significant degree (four
system designed to evaluate anxiety, social alienation, if mood is only irritable) (for past episodes, because of memory
uncertainty, and feelings of being controlled. They have difficulty, one less symptom is required):
developed this primarily as a method of defining and 1. More active than usual—either socially, at work, sexually—or
differentiating schizophrenic thought. physically restless
The methods of Weintraub and Gottschalk and col¬ 2. More talkative than usual or felt a pressure to keep talking
leagues require individual scoring of phrases and clauses in 3. Flight of ideas or subjective experience that thoughts are
transcribed samples of speech. Thus they are necessarily racing
4. Inflated self-esteem (grandiosity, which may be delusional)
time-consuming and, to some extent, dependent on the 5. Decreased need for sleep
subjective judgment of the scorer. Other experiments in 6. Distractability, ie, attention is too easily drawn to unimpor¬
content analysis have developed as a way of surmounting
tant or irrelevant external stimuli
these problems. Several investigators have attempted to 7. Excessive involvement in activities without recognizing the
analyze content by developing "dictionaries" or sets of high potential for painful consequences, eg, buying sprees, sexual
word categories that group together words considered to indiscretions, foolish business investments, reckless driving
share a similar psychological significance.-4 For example, C. Overall disturbance is so severe that at least one of the
all words dealing with the concept of failure would be following is present:
enumerated under this category. After a series of these 1. Meaningful conversation is impossible
dictionaries have been developed and their reliability and 2. Serious impairment socially, with family, at home, or at
validity determined, they can be used to analyze vocabu¬ work
3. In the absence of No. 1 or 2, hospitalization
lary content through more accurate and efficient comput¬ D. Duration of manic features at least one week (or any
erized methods. Such computerized content analysis has duration if hospitalized).
been used to analyze a wide variety of speech samples,
E. None of the following, which suggest schizophrenia is pres¬
ranging from the political pronouncements of foreign ent:
statesmen to spontaneous productions by schizophrenics. 1. Delusions of being controlled or of thought broadcasting,
Its application to psychiatric populations has, however, insertion, withdrawal
or
been quite limited to date. 2. Hallucinations of any type throughout the day for several
Thus, a variety of methods for analyzing speech and days or intermittently throughout a one-week period, unless all of
behavior each sentence was also coded to indicate sentence type: simple,
C. Dysphoric features of illness lasting at least one week. compound, complex, compound-complex, and fragment. This
Definite if lasted more than two weeks, probable if one to two method of coding also permitted an examination of sentence
weeks. length.
D. Sought or was referred for help from someone during the Several speech samples were coded independently by each of the
dysphoric period or had impaired functioning socially, with family, investigators. Since codings differed on only 1.5% of the words,
at home, or at work. this was considered to represent suitable interrater reliability.
E. None of the following, which suggest schizophrenia is pres¬ Thereafter coding was divided between the two investigators,
ent: with each taking half the manic sample and half the depressed
1. Delusions of being controlled or of thought broadcasting, sample in order to randomize any systematic error that might
insertion, withdrawal
or occur.
2. Hallucinations of any type throughout the day for several Other methods were used to examine aspects of speech content,
days or intermittently throughout a one-week period, unless all of such as vocabulary and word choice, as opposed to the above
the content is clearly related to depression or elation syntactical aspects. At the simplest level, richness or convention¬
3. Auditory hallucinations in which either a voice keeps up a ality of vocabulary was examined by determining what
running commentary on the patient's behaviors or thoughts as percentage of words used by the patients were among the 1,000
they occur, or two or more voices converse with each other. most commonly used words as determined by the Lorge-Thorndike
4. At some time during the period of illness had delusions or Dictionary. Which particular words were used most frequently by
hallucinations for more than one month in the absence of promi¬ each subject was also determined. In addition, the lexical diversity
nent affective (manic or depressive) symptoms (although typical of each subject was determined by calculating the type-token
depressive delusions, such as delusions of guilt, sin, poverty, ratio. The number of negators (no, not, never, etc) and the number
nihilism, or self-deprecation or hallucinations of similar content of qualifiers (perhaps, if, maybe, etc) were also determined for
are permitted) each subject, using a standard predetermined list.
5. Preoccupation with a delusion or hallucination to the relative In an attempt to achieve a more sophisticated approach to
exclusion of other symptoms or concerns (other than delusions or vocabulary and word choice, techniques of content analysis were
guilt, sin, poverty, nihilism, or self-deprecation or hallucinations also used. The most recent revision of the Harvard Psychosociolog-
with similar content) ical Dictionary, the Harvard IV-3, was obtained from Phillip
Mean SD Mean SD
No. of sentences
Simple 13.27 8.00 13.31 8.44 0.02 NS
Compound 280 1.90 2.13 1.15 1.16 NS
Complex 9.53 3.44 8.19 3.19 1.09 NS
Compound-complex 3.20 1.37 3.81 2.23 0.88 NS
No. of fragments 4.20 2.48 3.69 2.68 0.53 NS
No. of sentences in 400-word sample 33.00 9.54 31.13 10.62 0.50 NS
Stone and his associates. This dictionary divides 8,700 words or d. Personalization: It was predicted that manies would show
word senses into 170 content categories. Since using all 8,700 word more preoccupation with themselves, as reflected in increased use
senses and 170 content categories was thought to be too large an of first-person
pronouns.
undertaking for a pilot study of this type, 28 categories were Time orientation: It was predicted that depressives would be
e.
selected as being of possible relevance to affective disturbance. more preoccupied with the past, as reflected by the use of more
These categories contained words that tend to denote or connote past-tense verbs and more adverbs referring to time and place.
such ideas or feelings as achievement, failure, abandonment, /. Concrete vs abstract usage: It was predicted that manies
hostility, submission, strength, weakness, virtue, vice, disorder, or would be more concrete and depressives more abstract, as
negation. Each of these categories contained from 10 to 37 words. reflected by manies using more concrete nouns referring to places
The specific 28 categories used were: INCR, IMPLNEG, HOST, and things and depressives using more abstract nouns referring to
FEEL, ABANDON, EXPRS, EXERT, EVAL, EMOT, DISORDR, qualities or ideas.
DECR, CAUSAL, CHANGE, ACTV 3, ACH, FALL, WEAK 3, g. Verb-adjective ratio: This can be calculated as a verb-
VIRTUE, VICE, UNDRST, SUBM, STRNG 3, SOLVE, QUALIF, adjective, verb-noun, or verb-noun plus adjective ratio. If a higher
POWER, OVRST, NGTV 3, INDEF. ratio is associated with greater emotional instability, one would
Speech samples were transferred to computer cards, as were the expect a higher ratio in manic patients.
Lorge-Thorndike Dictionary and the 28 categories for content h. State of being-Action Verb Ratio: It was predicted that
analysis. The various frequency counts of word choice, and syntac¬ depressives would have a higher ratio, which would serve as an
tical elements, and vocabulary were all determined by computer¬ index of anergy.
ized analysis, using either stock programs locally available or 4. Content analysis: It was predicted that manies would use
programs written by one of the investigators. (B.P.) more words from the groups dealing with concepts such as
These data were used to test a number of hypotheses concerning strength or achievement, while depressives would choose words
several variables in structure and content of speech in affective reflecting a concern with weakness or failure.
disorder.
1. Lexical diversity: It was predicted that manies would have RESULTS
greater lexical diversity as reflected in higher type-token ratios The results of data analysis illustrate quite well how
and more words not occurring in the Lorge-Thorndike. difficult it is to predict language behavior on the basis of
2. Syntactical complexity: It was predicted that manies would
tend to use longer sentences and employ more complicated syntax
clinical experience. Subjective impressions were not always
as reflected in more compound, complex, and compound-complex supported by objective information, and a considerable
sentences and fewer simple sentences. It was also anticipated that number of the hypotheses were not proved.
they would use more fragments. As shown in Table 1, the depressives and manies did not
3. Frequency of syntactical elements: These were subdivided differ in lexical diversity. Although the manies did have a
into several groups that might reflect similar aspects of speech. slightly higher type-token ratio, suggesting a wider range
a. Vagueness: It was predicted that depressives would show of word choice, this was not statistically significant. Like¬
more vagueness as reflected by an increase in such syntactical
elements as indefinite adjectives, state of being verbs, and
wise, the manies used slightly fewer "commonly used"
relative, demonstrative, and indefinite pronouns.
words, as represented by the Lorge-Thorndike Dictionary,
but the difference was not statistically significant.
6. Colorfulness of speech: It was predicted that manies would
have more colorful or emotional speech, as reflected in more
As Table 2 demonstrates, the manies also did not show a
adverbs, adjectives, nouns, and action verbs. significant difference in syntactical complexity. Both
c. Use of qualifiers: It was predicted that depressives would manies and depressives used similar numbers of simple
tend to qualify their statements more often, as reflected by the sentences, and this tended to be the most common sentence
use of more modifying adverbs. type in both groups. They also did not differ significantly
Mean SD Mean SD
Vagueness
Indefinite adjectives 15.13 4.56 18.38 5.54 1.72 NS
Relative demonstrative and indefinite pronouns 25.60 6.63 24.38 5.73 0.53 NS
State of being verbs 61.13 13.35 49.44 9.45 2.74 .02
Colorfulness
Adverbs 46.60 8.25 39.44 7.19 2.50 .02
Action verbs 45.93 16.20 57.63 8.17 2.48 02
Adjectives 40.40 11.27 48.44 8.27 2.20 .05
Concreteness
Concrete nouns 31.20 7.35 43.94 11.73 3.48 .01
Abstract nouns 11.73 6.18 13.59 6.99 0.72 NS
Nouns 42.93 7.01 57.44 9.99 4.60 .001
Qualifiers
Modifying adverb 30.87 8.92 21.56 5.19 3.46 .01
Personalization
First-person pronouns 38.87 7.08 31.69 5.31 3.10 .01
Personal pronouns 69.93 9.17 61.50 11.06 2.25 .05
Time orientation
Past-tense verbs 24.53 14.35 17.81 14.43 1.26 NS
Adverb Indicating time 10.40 4.29 13.81 1.82 NS
in the numbers of compound, compound-complex, or difference significant at the .05 level. They used more past-
complex sentences used, and both used nearly the same tense verbs and therefore showed some preoccupation with
number of fragments. Depressives tended to use slightly the past, but the results did not reach statistical signifi¬
shorter sentences, but again the difference was not signif¬ cance, and they did not use significantly more adverbs
icant. referring to time and place.
Table 3 shows the frequency of syntactical elements in Table 4 contains a series of ratios that were calculated to
the two patient groups, and in this area the manies and permit comparison of our data with those of other studies.
depressives were often different, although not always in Each of these ratios is statistically significant, although
the direction predicted. As hypothesized, depressed slightly less so than if the various syntactical elements are
patients tended to show more vagueness, although only on compared singly. Contrary to prediction, the depressives
one index. They did not use significantly more indefinite have a higher verb-adjective ratio than the manies. They
adjectives or relative, demonstrative, and indefinite also have a higher verb-noun and verb-noun plus adjective
pronouns, but they did use significantly more state-of- ratios. These differences are significant at the .05, .02, and
being verbs at the .02 level. Manies, on the other hand, did .02 levels, respectively. If a ratio of state of being-action
tend to have more colorful language. Their use of action verbs is constructed, then the depressed patients also are
verbs and adjectives was greater at the .05 and .02 levels, higher at the .05 level. This index is probably relevant
respectively, but the depressed patients did use more because it indicates that the verb-adjective ratio cannot
adverbs with a difference significant at the .02 level. truly be considered an action quotient, since it does not
The issue of concrete vs abstract usage is somewhat reflect a high use of action verbs among the depressed
obscure. The manic patients tended to use considerably patients.
more nouns, and they therefore used both more concrete Table 5 reports the results of content analysis, which
nouns and more abstract nouns than the depressed were statistically significant. As expected, manies tended
patients. The difference in abstract nouns is not statisti¬ to choose words that reflected concern with power and
cally significant, however, while the differences in nouns achievement, but somewhat surprisingly the depressives
generally and in concrete nouns are significant at the .001 were higher in the overstatement category. Since the total
and .01 levels, respectively. The manies, therefore, were number of dictionaries examined was 28 and since only
definitely more concrete. three were found to differentiate the two groups signifi¬
As predicted, the depressed patients tended to qualify cantly, the differentiation may be purely on the basis of
their statements often, as reflected in their use of
more chance.
more qualifying adverbs, with the difference significant at Table 6 compares the results of our analysis of manic and
the .01 level. On the other hand, the hypotheses concerning depressive speech expressed in percentages with that of
personalization and time reference were not supported by Lorenz and Cobb. Since they reported their data in
the data. The depressed patients, rather than the manies, percentages and did not report means and standard devia¬
tended to show a greater preoccupation with themselves, as tions, statistical comparison is not possible, but the results
reflected in their greater use of the first person pronoun, for manic patients are strikingly similar and suggest that
with the difference significant at the .01 level. They also data of this type can be replicated. Their patient sample
tended to use more personal pronouns generally, with the size was smaller (ten) and their word sample size larger
Table 5—Content Analysis pretation and the relatively short length of the sponta¬
neous speech samples may well have produced an artifac-
Depressives Manies tual homogeneity in word choice and sentence type. Subse¬
(N 15)
=
(N = 16)
quent investigations in this area should probably be
Mean SD Mean SD limited to "spontaneous speech" only and increase the word
Power (18*) 9.26 2.67 13.19 3.86 3.17 .02 sample to at least 500 words per patient and possibly 1,000
Overstatement (19) 17.53 5.48 12.00 4.83 2.88 .02 words. Most of the content analysis dictionaries consist of
Achievement (37) 7.53 2.75 10.19 3.15 2.42 .05 20 to 30 words, and a 400-word sample is probably not long
'Numbers in parentheses are the number of words In the category.
enough to assess the use of this relatively small number of
words. Further, subsequent studies should probably control
for verbal intelligence quotient rather than using consecu¬
Table 6.—Syntactical Elements in tive admissions, since vocabulary size and intelligence may
Two Studies of Speech in Affective Disorders well play a significant role in syntactical complexity and
lexical diversity. The higher educational level of the manies
% of Words
may have distorted results in some way, although neither
Lorenz & Cobb2 Andreasen & Pfohl group is of a very high educational level.
(Current Study)
Nevertheless, manic and depressed patients did differ
Normals Manies Manies Depressives from one another substantial number of variables
on a
Nouns 16.7 14.9 13.3 9.9 probably not related to education. The
analysis of syntac¬
Adjectives 12.2 9.6 7.0 5.9 tical elements was particularly useful in distinguishing
Adverbs 12.5 11.7 9.1 10.8 between the two groups, and several working hypotheses
Verbs 16 8 22 3 24.8 24.8 were validated. The speech of the depressives was charac¬
Pronouns 13.8 18.2 19.9 22.1 terized by the use of more state of being verbs, adverbs,
Prepositions 10.4 8.3 5.6 5.9 modifying adverbs, first-person pronouns, and personal
Conjunctions 8.9 7.5 8 1 8.9 pronouns, while the manies used significantly more action
Articles 6.4 5.9 5.5 3.5 verbs, adjectives, concrete nouns, and nouns generally.
Although the characteristics of speech that these syntac¬
tical elements are assumed to represent are somewhat
(1,000 words), but nevertheless none of the categories arbitrary and theoretical, these results imply that depres¬
differ by more than 3%. Oddly, our depressed patients tend sive speech tends to be more vague, qualified, and person¬
to differ from Lorenz and Cobb's normal subjects in a more alized, while manic speech is more colorful and concrete. If
extreme way than the manies, suggesting that "normality" one wishes to reject the descriptive categories altogether
is not necessarily a mean between mania and depression. as too arbitrary, one nevertheless is left with the clear
COMMENT
implication that depressed patients tend to qualify more,
to talk more in terms of a "state of being," and to talk more
Because it is a pilot study, this investigation deals with a both about themselves and other people. Manies, on the
large number of linguistic variables. A considerable other hand, tend to talk more about things than about
number, thought to be potentially promising, were not of people, to discuss them in terms of action, and to use more
any value in discriminating between the two groups statis¬ adjectives to describe them. Because our data on manies
tically. In particular, measures of lexical diversity such as are so similar to those of Lorenz and Cobb, it seems likely
the type-token ratio have been of considerable value in that these positive findings can be replicated in future
other linguistic studies of psychiatric populations. The studies.
content analysis dictionaries have been described as a very The results of one familiar linguistic variable, the verb-
interesting method for examining the emotional tones adjective ratio, were particularly surprising. Originally
expressed in samples of language. The negative results described as an "action quotient" or an index of instability,
obtained with these two linguistic tools were particularly it has been consistently higher among psychiatric groups
disappointing. In addition, greater differences in syntac¬ than normals. If it were indeed either an action quotient or
tical complexity were also anticipated. an index of instability, one would anticipate that it would
However, these negative results may have been due to an be higher in manies than depressed patients, but the
error in experimental design, which should be remedied in reverse was true. Other aspects of the data analysis
subsequent studies. The use of 80 words of proverb inter- suggest that one must consider not only the quantity of