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Bio-Medical RF Simulations

with CST Microwave Studio®

 Biological Models

 Specific Absorption Rate (SAR)

 Bio-Medical Examples

www.cst.com | May-10
Biological Models
The right choice of the biological model is essential for the reliability
of a SAR or EMI simulation.
SAM Phantom,
CST Voxel Family
homogeneous
models
Visible Human
voxel data

other voxel data

www.cst.com | May-10
Homogeneous Hand/Body Models
• New .obj import allows import of biological models, e.g. from
Poser® 8 (http://my.smithmicro.com/win/poser/index.html)
• For most high frequency applications fully sufficient
• Simulate much faster then voxel models

www.cst.com | May-10
SAM - Standard Anthropomorphic Model
• Originally created for measurements plastic shell
• Shape specified in IEEE/CENELEC/IEC tissue
standards simulant
• Filled with homogeneous glycol-containing liquid
tissue-simulant liquid, only two materials (TSL)
for simulation
• Virtual prototyping through simulation

Frequency dependent material


properties (according to
standard) can be modelled by
dispersive materials via
tabulated input.

Only one simulation run for


broadband results!!
www.sam-phantom.com
www.cst.com | May-10
CTIA Hand Models
Hand fold

Hand narrowdata

Hand monoblock

Hand PDA
www.cst.com | May-10
CST Voxel Family
CHILD

BABY

KATJA
(pregnant)

LAURA DONNA EMMA GUSTAV


www.cst.com | May-10
CST Voxel Family

 Macros -> Solver -> Calculate


Human Material Properties

www.cst.com | May-10
HUGO
Available in
different
resolutions

Materials of
interest can be
chosen

Visible Human Project


produced by the National Library of
Medicine (NLM), Maryland
http://www.vr-laboratory.com/

www.cst.com | May-10
Cole-Cole-Materials

www.cst.com | May-10
SAR: Overview and Background
SAR – Specific Absorbtion Rate
A measure for electromagnetic energy absorbed by biological
tissue mass when exposed to radiating device (e.g. mobile phone)

Unit of SAR: W/kg


E P J 2 2
SAR    P: Power loss density
 2 2  E: Electric field strength
J: Current density
s: Conductivity
Typically averaged over pre-defined mass r: Density

www.cst.com | May-10
Averaging Procedure
1. Point of avg. SAR calculation
2. Search for 10 g cube (iteratively)
3. Integrate losses in cube

At boundary treatment depends on


chosen averaging standard:
IEEE C95.3, IEEE 1528.1, CST C95.3
CST legacy

The „constant volume“ assumption uses an averaged cube size:


- Faster (no iterative search for cube with correct mass)
- Only approximative (not according to official SAR standard)
www.cst.com | May-10
SAR Standards under Development
• Several guidelines and standards specify SAR safety limits (i.e.
ICNIRP).
• Standards like IEEE 1528 regulate measurement methods for
practical assessment of compliance.
• A simulation standard IEEE 1528.X is in development
• 1528.1 requirements for hexahedral time domain codes (end
of 2010)
• 1528.2 application to cars with passenger/bystander (~2011)
• 1528.3 application to mobile phones near head (~2011)
• 1528.4 requirements for tetrahedral frequency domain codes
• CST participates in standards committee.
• IEEE C95.3 Annex E specifies SAR averaging scheme for
simulation.
• CST MICROWAVE STUDIO® has already been approved by the FCC
(USA) to comply with hex td standard drafts.
www.cst.com | May-10
Visualization of SAR
2D or 3D plot including information about position of the maximum

www.cst.com | May-10
Visualization of Max. SAR Cube

www.cst.com | May-10
Dispersive Broadband Simulation
Typical requirement for dual band phones:

Re(er) Im(er)
0.9 GHz 41.5 17.98 (= 0.9 S/m)
1.8 GHz 40.0 13.98 (= 1.4 S/m)

Frequency dependent
material definition:
Second order dispersive
fit for tabulated values,
only one simulation run
required

www.cst.com | May-10
Dispersive Broadband Simulation
S-Parameter comparison: Compared material settings:
 Constant settings for 0.9 GHz
sim. time 45 min.
 Constant settings for 1.8 GHz
sim. time 45 min.
 Dispersive broadband fit
total sim. time: 57 min.

SAR value comparison:

0.9 GHz, 1g 1.35 1.31 1.74

0.9 GHz, 10g 0.96 0.93 1.13

1.8 GHz, 1g 0.69 1.32 1.32

1.8 GHz, 10g 0.99 0.83 0.83

Dispersive fit agrees very well for S-Parameter and SAR


values in both bands for only 25% extra simulation time
www.cst.com | May-10
Measured vs. Computed SAR Distribution
Example: 7T MRI endorectal coil
0 dB = 2.8 W/kg

Overall:
SAR computed
 1.08 – 1.15
SAR measured

Simulation
Measurement

Courtesy of Erwin L. Hahn Institute Essen,Germany


www.cst.com | May-10
Magnetic Resonance Imaging (MRI)
Three EM-fields needed for imaging
• STRONG magnetostatic field (human: 1 – 9.4
Tesla, up to 21 T for animals)
Mostly superconducting magnets, aligning the
spinning protons
-> M-Statik Solver

• Gradient field for positioning (in kHz range)


-> Magneto-Quasistatik Solver, LT-Solver

• HF field to excite spinning protons and


receive relaxation signal (60 – 500 MHz)
Rotating B-Field most interesting (B1+)
-> Both T- and F-Solvers are of intererst!

Most interesting for MRI R&D


www.cst.com | May-10
Design Challenge: Increase SNR of image
SNR ~ static biasing field ~ spin resonance frequency fres

For 7T MRI -> fres = 297 MHz -> lbody ~ 13 cm


-> It is difficult to obtain homogeneous field
distribution inside body, specialized coils
required

Safety issue: SAR ~ fres2


-> SAR critical for higher fres

-> Alternative: queck directly body


temperature increase, bioheat solver!

Advantages of CST: Complete Technology, Static, LF, T, F and


bioheat solvers in one frontend, Voxel Family, fast SAR, etc…

www.cst.com | May-10
8 Channel Head Coil

Courtesy of Erwin L. Hahn Institute Essen,Germany


www.cst.com | May-10
8 Channel Head Coil
Vs/m²
|B1 +| SAR voxel

[°]
arg(B1+) SAR 10g

www.cst.com | May-10
8 Channel Head Coil
location of max. SAR10g in
left shoulder for off-centre
position of head location of max. SAR on
left side of the head
max. perm. power = 23 W
(CW)

SAR10g most critical aspect SAR10g SARhead

25 W max. perm. power 27 W 33 W

SAR10g

www.cst.com | May-10
Spine Loop Array
• loops overlapped and shifted

• 70 cm cable length

• box with TR-switches + pre-amps

20 cm
x

43 cm

www.cst.com | May-10
Comparison to Measurement
Measurement Simulation
max B1+ = 15.9 µT max B1+ = 13.5 µT

www.cst.com | May-10
SAR Compliance
critical aspect: localized SAR (10g averaged)

www.cst.com | May-10
Microwave Breast Cancer detection

Dr. Maciej Klemm, Electromagnetics Group, Centre for Communications


Research (CCR), University of Bristol, United Kingdom
e-mail: m.klemm@bristol.ac.uk

www.cst.com | May-10
Model setup and clinical results
• dipole antennas
• dispersive tissues
• inhomogeneous breast !
• model 30-40M cells
• full imaging (30 simulations)
takes about 10h (hardware
accelerated; 4 GPU cards)

www.cst.com | May-10
Pace Maker Simulation
Complete Technology:

T-Solver

T-Solver F-Solver

www.cst.com | May-10
Results at 400 MHz
Inside biological tissue phantom

SAR

E-Field
Averaging Cube for
max SAR

www.cst.com | May-10
Pacemaker inside Human Body Model

www.cst.com | May-10
Cardiac Pace Maker
Frequency dependent field coupling into a Cardiac Pace Maker (CPM)

Courtesy of Lehrstuhl für Theoretische Elektrotechnik, Bergische Universität Wuppertal, Germany


www.cst.com | May-10
BABY besides Baby-Phone

Stimulated power: 500 mW at 865 MHz

Max. SAR value (averaged over 10g): 0.02 W/kg


(well below accepted maximum of 2 W/kg for public exposure)

Courtesy of Lehrstuhl für Theoretische Elektrotechnik, Bergische Universität Wuppertal, Germany


www.cst.com | May-10
New CST Examples!

Can only be opened by customers who have


-Voxel Import
- BioModel License
-> offer for evaluation license!!
www.cst.com | May-10
Summary
 CST STUDIO SUITE offers a wide range of tools for
bio-medical simulations (MRI, cancer treatment,
diathermy, implants, etc.)

 Both flexible homogeneous and detailed voxel models


are available

 „Complete Technology“ allows combined simulations


from static to GHz including circuit simulation

 SAR and Bio-Thermal simulations help to improve


performance and safety of medical devices

www.cst.com | May-10
Appendix

www.cst.com | May-10

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