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Psychiatry Research 196 (2012) 123–132

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Psychiatry Research
journal homepage: www.elsevier.com/locate/psychres

Taxometric analyses of paranoid and schizoid personality disorders


Anthony Olufemi Ahmed a,⁎, Bradley Andrew Green b, Peter Francis Buckley a, Megan Elizabeth McFarland b
a
Department of Psychiatry and Health Behavior, Georgia Health Sciences University, 997 Saint Sebastian Way, Augusta, GA 30912, United States
b
Department of Psychology, University of Southern Mississippi, 118 College Drive, #5025 Hattiesburg, MS 39406, United States

a r t i c l e i n f o a b s t r a c t

Article history: There remains debate about whether personality disorders (PDs) are better conceptualized as categorical,
Received 2 February 2011 reflecting discontinuity from normal personality; or dimensional, existing on a continuum of severity with
Received in revised form 9 October 2011 normal personality traits. Evidence suggests that most PDs are dimensional but there is a lack of consensus
Accepted 11 October 2011
about the structure of Cluster A disorders. Taxometric methods are adaptable to investigating the taxonic sta-
tus of psychiatric disorders. The current study investigated the latent structure of paranoid and schizoid PDs
Keywords:
Paranoid
in an epidemiological sample (N = 43,093) drawn from the National Epidemiological Survey on Alcohol and
Schizoid Related Conditions (NESARC) using taxometric analyses. The current study used taxometric methods to an-
Personality disorders alyze three indicators of paranoid PD — mistrust, resentment, and functional disturbance — and three indica-
Taxometrics tors of schizoid PD — emotional detachment, social withdrawal, and functional disturbance — derived factor
Latent structure analytically. Overall, taxometrics supported a dimensional rather than taxonic structure for paranoid and
Schizophrenia spectrum schizoid PDs through examination of taxometric graphs and comparative curve fit indices. Dimensional
models of paranoid and schizoid PDs better predicted social functioning, role-emotional, and mental health
scales in the survey than categorical models. Evidence from the current study supports recent efforts to rep-
resent paranoid and schizoid PDs as well as other PDs along broad personality dimensions.
© 2012 Elsevier Ireland Ltd. All rights reserved.

1. Introduction Disorders — fifth edition (DSM-V) imminent, there has been a strong
push for a dimensional reorganization of PDs. A number of studies
The question of whether psychiatric disorders should be repre- have also presented viable dimensional alternatives to the predominant
sented categorically or dimensionally in diagnostic systems (e.g., categorical scheme, most of which suggest organizing personality
World Health Organization, 1992; American Psychiatric Association, pathology along three to seven broad domains (e.g., Cloninger et al.,
2000) remains a point of contention in psychiatry. This debate is espe- 1993; Harkness and McNulty, 1994; Cloninger, 2000; Livesley, 2003;
cially salient to personality disorders (PDs), which many argue are Shedler and Westen, 2004; Widiger and Simonsen, 2005).
best represented dimensionally (Clark et al., 1997; Widiger and Trull, In general, attempts at organizing PDs into broad dimensions have
2007). Categorical models consider diagnostic entities qualitatively dis- ensued without direct empirical evidence that they are actually
tinct from one another and non-pathology. Dimensional models, how- dimensional. Evidence supporting the superior predictive validity of
ever, view PDs as existing on a continuum of severity with normal severity scores relative to diagnosis in relation to clinically relevant
personality traits and attempt to represent PDs along a set of broad variables does not establish latent structure as inherently dimensional
facets of normal personality (Widiger and Trull, 2007). Critics highlight (e.g., Goedeker and Tiffany, 2008). Further, evidence that PDs can be
limitations of categorical representations of PDs including high rates of organized into dimensions via factor modeling does not provide direct
diagnostic co-occurrence, limited construct validity, and high rates of tests of their latent structure as dimensional rather than taxonic. Direct
subthreshold cases and Not Otherwise Specified (NOS) diagnoses (Clark empirical evidence of the relative viabilities of continuity and disconti-
et al., 1997; Widiger and Clark, 2000; Widiger and Trull, 2007). More- nuity models of PDs can be obtained using taxometric methods devel-
over, evidence suggests that dimensional models of PDs are better at oped by Meehl and colleagues (Grove and Meehl, 2009; Meehl and
predicting variables such as functional impairment, suicidal gestures, Yonce, 1994; Meehl, 1995; Meehl and Yonce, 1996; Waller and Meehl,
hospitalization, and criminal offender status than categorical models 1998). Taxometric methods determine latent structure by modeling
(Ullrich et al., 2001; Skodol et al., 2005; Morey et al., 2007). With the pattern of relationships among indicators of a construct, which are
the publication of the Diagnostic and Statistical Manual of Mental depicted graphically. Using a multiple hurdles framework, it requires
convergence across multiple procedures with the aid of consistency
tests and numerical indices (Meehl, 1995; Ruscio, 2007). Taxometric
investigations of the latent structure of PDs appear to support a dimen-
⁎ Corresponding author. Tel.: + 1 706 721 7874; fax: +1 706 721 1793. sional structure for most PDs investigated to date with a few exceptions
E-mail address: aahmed@geogiahealth.edu (A.O. Ahmed). (Haslam, 2003, 2007). Schizotypal PD has been the most extensively

0165-1781/$ – see front matter © 2012 Elsevier Ireland Ltd. All rights reserved.
doi:10.1016/j.psychres.2011.10.010
124 A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132

demonstrated to possess a taxonic structure (e.g., Tyrka et al., 1995; samples and indicators drawn from diagnostic interviews and a self-
Lenzenweger, 1999). report measure provided support for a dimensional structure.
The consensus that PDs likely exist on a continuum of severity The Arntz et al. study sampled only a few putative taxon members.
with normal personality traits wanes when Cluster A disorders are Of a sample of 1816, only 95 participants met paranoid PD diagnostic
in question. One reason for this departure relates to the perceived criteria. Although Monte Carlo simulations have demonstrated the
genetic/familial relationship between Cluster A disorders and schizo- ability of taxometric methods to detect low base rate taxons, there
phrenia. Studies have demonstrated that there is a higher rate of have been limited systematic studies of the threshold for the absolute
Cluster A disorders among relatives of individuals with schizophrenia size of the putative taxon required to obtain clear taxonic results via
when compared to controls (Kendler et al., 1993; Chang et al., 2002; visual inspection. Schmidt et al. (2004) suggested a threshold of 30
Kendler et al., 2006). Given evidence of the taxonic structure of taxon members; however, this was not based on a systematic evalu-
schizophrenia phenotypes or schizotypy (Tyrka et al., 1995; ation of taxon group size in combination with other data conditions.
Lenzenweger, 1999), Cluster A symptoms may demonstrate a taxonic For example, whether the threshold of 30 would still be reasonable
structure. Meehl (1962, 1990) suggested in his theory that schizo- if the total sample size was much more than the 300 minimum
phrenia emerges from a genetic defect that leads to hypokrisia, a recommended for taxometric studies (Meehl, 1995) is an empirical
generalized CNS defect or neurological aberration caused by neuro- question. Further investigation with larger taxon group sizes may
chemical, neurophysiological, or neuroanatomical deficiencies. confirm or disconfirm their latent structure findings. We investigated
Hypokrisia leads to schizotaxia characterized by “neurointegrative the latent structure of paranoid PD in a large epidemiological sample
defect” that leads to social avoidance and sociocognitive deficits. Schi- using taxometric methods. Using a large epidemiological sample to
zotaxia results in the vulnerability to schizophrenia and spectrum dis- study the latent structure of paranoid PD increases our likelihood of
orders by working in tandem with other predispositions and including more putative taxon members in the analysis. In fact, the
environmental factors such as personality traits, life stressors, social number of individuals meeting diagnostic criteria for paranoid PD in
learning, and polygenetic factors to result in a schizotypic personality the sample is 2105. Given that there have been no taxometric studies
organization. Although neither equivalent to nor isomorphic with of the DSM-defined schizoid PD; our study consolidates this gap in
DSM diagnosis of schizophrenia or Cluster A PDs, schizotypy overlaps the taxometric literature on PDs by examining if the 1425 individuals
with the DSM constructs and some schizotypes do in fact develop meeting diagnostic criteria for schizoid PD in the survey represent a
Cluster A PDs or schizophrenia. qualitatively distinct class. Unfortunately, the survey did not collect
Although their study supported ultimately a dimensional structure data on schizotypal PD so we were unable to investigate the latent
for paranoid PD, Edens et al. (2009) suggested the possibility that is structure of schizotypal PD in the study.
similar to the relationship between schizotaxia, schizotypal personality,
and schizophrenia; a paranoid taxon could result in vulnerability to 2. Method
paranoid PD that could work in tandem with other factors to increase
the risk of developing paranoid schizophrenia or delusional disorder. 2.1. Participants
Similarly, a schizoid taxon may be present in schizoid PD that subse-
The study analyzed the responses of participants on the 2001–2002 National Epi-
quently results in negative symptoms characteristic of schizophrenia demiologic Survey on Alcohol and Related Conditions (NESARC; National Institute on
in some individuals (American Psychiatric Association, 2000; Chang et Alcohol Abuse and Alcoholism (NIAAA), 2006). The survey obtained a representative
al., 2002). Social anhedonia, a core feature of schizophrenia and schizoid sample (N = 43,093) of individuals living in the United States at least 18 years of age
PD has received attention in taxometric studies, which suggest a taxonic and currently non-institutionalized. African-Americans (19.1%) and Hispanics (19.3%)
were well represented in the sample. The age of participants ranged from 18 to 98
structure (Blanchard et al., 2000; Horan et al., 2004). It is noteworthy
(M = 46.40, S.D. = 18.18). Women represented a majority (57%) of the sample. Individ-
that although Golden and Meehl (1979) reported a taxometric study uals who participated in the survey completed diagnostic interviews assessing a range
of schizoid taxon or schizoidia, the construct investigated was more con- of psychiatric disorders including substance use problems, mood disorders, anxiety
sistent with a schizotypic personality organization described in Meehl's disorders, and PDs. The psychiatric symptoms were assessed using the NIAAA Alcohol
Use Disorders and Associated Disabilities Interview Schedule — DSM-IV Version
theory. Thus, there have been no taxometric studies of schizoid person-
(AUDADIS-IV;Grant et al., 2001). The AUDADIS was designed to be administered by
ality or schizoid PD. trained lay interviewers. Grant et al. (2003) obtained test–retest reliabilities ranging
In addition, taxonicity has yet to be demonstrated for paranoid PD. from .50 to .79 for PD dimensions (10-week retest interval) in a subsample of 315 re-
Arntz et al. (2009) conducted a series of taxometric analyses in a sample spondents who completed the original NESARC survey. Personality pathology as mea-
of 1879 individuals drawn from various mental health facilities, prisons, sured by the PD section of the AUDADIS-IV has been demonstrated to be associated
with disability as measured by subscales of the Short-Form 12-Item Health Survey,
and hospitals across Europe. One of the constructs investigated was
Version 2 (SF-12v2) (Pulay et al., 2008).
paranoid PD, the indicators of which they drew from the Structured The paranoid PD portion of the survey included 18 items assessing suspiciousness and
Clinical Interview for DSM-IV Axis-II Personality Disorders (SCID-II). pervasive mistrust in personal relationships as well as items assessing disturbance in
Arntz et al. analyzed the indicators using the MAMBAC, MAXEIG, and occupational and relational functioning. The schizoid PD portion of the survey included
20 items assessing emotional constriction, detachment from interpersonal relationships,
L-Mode taxometric procedures and determined latent structure by
social isolation, and functional problems.
examining graphical outputs with simulated comparison data, and
comparative curve fit indices. Their results across procedures supported
a dimensional structure. Similarly, Edens et al. (2009) examined the 2.2. Analyses

latent structure of paranoid PD in two studies using taxometric To investigate the latent structure of paranoid and schizoid PDs, responses on the
methods. The first study examined the latent structure in a clinical sam- survey were submitted to taxometric procedures including MAMBAC (Mean Above
ple (n = 713) drawing indicators of paranoid PD from a diagnostic in- Minus Below A Cut; Meehl and Yonce, 1994), MAXEIG (MAXimum EIGenvalue;
terview. The second study examined latent structure in a clinical Waller and Meehl, 1998), and L-Mode (Latent Mode Factor Analysis; Waller and
Meehl, 1998). The MAMBAC procedure is implemented with at least two indicators
(n = 1246) and community sample (n = 1000), drawing indicators
of the construct. One of the indicators is designated as the input indicator and the
from the Personality Assessment Inventory (PAI). Both studies imple- other is designated as the output. Successive cuts are made on the input indicator
mented the MAMBAC and MAXCOV taxometric procedures and also and at each cut; the difference (d) between the mean score of cases falling above the
compared the criterion-related validities of both a taxonic and a dimen- cut and cases falling below the cut on the output variable is computed. A graph of
sional model. Overall, the results of their study supported a dimensional the successive cuts (50 in the current study) on the x-axis is plotted against d on the
y-axis. For the MAMBAC analyses, each indicator served as both the output, paired
model through an examination of taxometric plots, fit indices, and the with another indicator as input, and input, paired with another indicator as output,
relative criterion-related validities of a taxonic versus dimensional yielding one MAMBAC graph per each permutation of indicator pairs. Taxonic situa-
model. The convergence of evidence from community and clinical tions usually yield single-peaked d(x) functions with the location of the peak
A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132 125

corresponding to the base rate of the taxon. Dimensional situations typically yield a For the remaining 10 schizoid PD items, a two-component solution accounting for
“concave up” graphical function. 38.25% variance in the model was selected. The first component labeled emotional de-
The MAXEIG procedure is implemented with at least three indicators of the construct. tachment comprised five items assessing constriction in emotional expression and
One of the indicators is designated as the input and the remaining indicators are designat- emotional disconnection from others. The second component labeled social withdraw-
ed as outputs. Successive overlapping windows (50 in the current study) are created on al comprised five items assessing social isolation and lack of interest in engaging with
the input variable with adjacent windows sharing 90% of their cases. At each window, others socially. We created two additional candidate indicators for both paranoid and
the first eigenvalue reflecting the covariation among all of the output indicators is schizoid PDs by summing items into scales guided by the component solutions.
obtained. The graph of the eigenvalue (on the y-axis) is plotted against the windows Table 1 summarizes the items used in the study and their corresponding scales.
created on the input indicator (x-axis). Taxonic situations will yield single-peaked condi- The paranoid and schizoid PD scales were submitted to MAMBAC, MAXEIG, and L-
tional eigenvalue functions with peaks representing the location of the hitmax, whereas Mode to determine the latent structure of paranoid and schizoid PDs in the sample.
dimensional situations yield plots with no apparent peaks. In MAXEIG analyses, each indi- Following Meehl's (1995) recommendation, indicators are evaluated to ensure ade-
cator served as an input with the remaining indicators serving as the multivariate output quate validities for detecting taxonicity (threshold d ≥ 1.25 separations between puta-
indicator for that analysis, yielding one MAXEIG graph per indicator. We configured tive taxon and complement groups) and adequate nuisance correlation — i.e., residual
MAXEIG to produce graphs of Bayesian posterior probability distributions for putative correlations not accounted for by group membership. To this end, we estimated the
taxon group membership for both the paranoid and schizoid PD analyses. Taxonic situa- validities and nuisance correlation of the data using the Indicator.Dist function in the
tions usually produce probabilities that cluster around 0 and 1, whereas dimensional program using DSM-IV diagnostic status as a priori classification. For paranoid PD, in-
situations produce probabilities that cluster around various values between 0 and 1, dicator validities ranged from 2.29 to 5.21 (M = 3.89, S.D. = 1.48). The average nui-
thus providing a useful inferential tool of latent structure. sance correlation within the taxon (r = 0.21, S.D. = 0.33) and complement groups
The L-Mode procedure conducts an exploratory factor analysis on the indicator vari- (r = 0.31, S.D. = 0.04) were acceptable. For schizoid PD, validities ranged from 1.68 to
ables and identifies latent structure by calculating factor scores for all cases using a one- 5.62 (M = 3.18, S.D. = 2.14) and nuisance correlation within taxon (r = 0.11,
factor latent variable model. L-Mode graphs the factor density plot of the distribution S.D. = 0.25) and complement groups (r = 0.19, S.D. = 0.21) were also acceptable. The
and the distribution is examined for local modes. If the construct of interest is taxonic, indicators for paranoid and schizoid PDs had average correlations of 0.54 and 0.35 re-
the distribution of factor scores should be bimodal. L-Mode estimates the base rate of spectively. We conducted taxometric runs using the same a priori classifications based
the taxon by using the location of the upper (right) and lower (left) modes of the research on DSM-IV diagnostic status using the “Supplied.Class” option in the program that al-
curve. On the other hand, dimensional situations should produce evidence of a unimodal lows class membership to be defined. We also generated simulated categorical com-
distribution of factor scores. It was conjectured that if the latent structure of paranoid PD parison data to accompany the research data using the same a priori classifications
was taxonic, the putative groups would have unequal mixing proportions. Thus, it was de- thus ensuring that identical populations of comparison data are being generated across
cided prior to analysis that the program would be configured to manually search for latent taxometric procedures.
modes following an initial visual inspection of the research curve to ensure that the right While not direct tests of latent structure, some researchers have recommended
mode was correctly located. that taxometric investigations also compare the relative validities of taxonic and di-
The shape of taxometric curves often deviates from the descriptions offered above, mensional models of psychiatric disorders to determine how well both models predict
usually due to factors such as non-normality, base rate, and levels of nuisance covariance relevant clinical variables (Watson, 2006). It may be that even when a construct is
and indicator validity. The graphical outputs of research data obtained from the taxo- taxonic, a dimensional model accounts for substantially more variance in relevant cri-
metric procedures were interpreted by visual inspection aided by comparison to graphical terion variables that the utility of dimensional assessment is still substantiated. In the
outputs obtained from simulated taxonic and dimensional data, generated to match the current study, three variables in the NESARC data were designated as external vari-
distributional characteristics of the research data including sample size, skew, kurtosis, ables for investigating the comparative validity of categorical and dimensional models
and indicator correlations. For each analysis, 100 to 1000 samples of taxonic and dimen- of paranoid and schizoid PDs. These were the Mental Health Component, Social Func-
sional comparison data were generated. In addition to visual inspection aided by simulat- tioning, and Role-Emotional Function scales derived from the Short-Form 12-item
ed comparison data, the use of simulated taxonic and dimensional datasets allows a Health Survey (SF-12v2), which was administered in the NESARC survey. Norm-
Comparison Curve Fit Index (CCFI) to be computed to compare the relative fits of taxonic based scores on the scales range from 0 to 100 (M = 50), with lower scores on the vari-
versus dimensional latent structures to the data. CCFI values range from 0 (strongest sup- ables generally denote poorer functioning. The scales have been shown to be associat-
port for dimensional structure) to 1 (strongest support for taxonic 0.structure), with ed with personality pathology (Pulay et al., 2008). We compared the severity scores to
values close to 0.50 representing ambiguous results. In the current study, CCFIs are imple- DSM-IV diagnostic status in terms of their association with external variables. We
mented with dual thresholds with values between 0.40 and 0.60 suggesting ambiguous obtained severity scores by summing the number of endorsed items into a total sever-
results. CCFIs have demonstrated excellent accuracies at distinguishing between taxonic ity indicator. Whereas severity scores represented the dimensional model, DSM-IV di-
and dimensional data in several large-scale Monte Carlo studies under data configurations agnostic status represented the categorical model.
that violate multiple statistical assumptions (Ruscio and Kaczetow, 2009; Ruscio et al.,
2010). Taxometric analysis implements a multiple hurdles consistency testing approach
to determining correct latent structure by requiring that conclusions be drawn based on
3. Results
converging evidence from multiple methods (Meehl, 1995). Ruscio et al. (2010) deter-
mined that this is best implemented with CCFIs by computing the mean CCFI across taxo- 3.1. Latent structure of paranoid PD
metric methods. When mean CCFIs are implemented with dual thresholds in inferring
latent structure, CCFIs distinguish taxonic from dimensional Monte Carlo samples with
3.1.1. MAMBAC analysis
over 99% accuracy (Ruscio et al., 2010). The analysis configurations were carried out
using Ruscio's taxometric program (Ruscio, 2010) implemented in the R Computing Envi- MAMBAC (all pairs) produced six individual graphs, five of which
ronment (R Foundation for Statistical Computing, 2010). appeared to be rising, and one demonstrating a “hook” at the high
end of the distribution. The average MAMBAC curve appeared to be
2.3. Construction of indicators rising, consistent with a dimensional structure. Comparing the aver-
age MAMBAC curve to the curves produced by the simulated taxonic
Indicators for the taxometric analyses were created by first identifying items mea- and dimensional data, the average curve appeared to equally fit both
suring the symptoms of paranoid and schizoid PDs. Following recommendations by
simulations across the entire distribution (Fig. 1).
Cole (2004) and Beauchaine (2003), the current study used composite indicators rath-
er than item level indicators to increase the likelihood of obtaining stable taxometric
curves with clear resolution. In the NESARC survey, each item assessing DSM-IV PD 3.1.2. MAXEIG analysis
symptom was followed up with an item assessing social and/or occupational dysfunc- MAXEIG produced two individual curves that appeared to be ris-
tion phrased as “did this ever trouble you or cause problems at work or school, or with
ing and one that was flat or fluctuating around a mean eigenvalue.
your family or other people?” In all, 18 items assessed paranoid PD and 20 items
assessed schizoid PD. In the diagnostic algorithm for the NESARC survey, at least one The average curve appeared to be rising with no apparent peaks con-
of the criteria for diagnosis had to be associated with social and/or occupational dys- sistent with a dimensional structure. Fig. 2 depicts the average curve
function for a diagnosis to be assigned when the required number of symptoms has superimposed over curves produced by the simulated taxonic and di-
been met. mensional data. The average curve appears more consistent with that
To create candidate indicators for the taxometric analyses, we summed the social/
occupational dysfunction items into two functional disturbance scales — one for each
of the simulated dimensional data.
construct. Next, we submitted the remaining items to principles components analyses
(PCA) with Promax rotation. For the remaining nine paranoid PD items, we selected a 3.1.3. L-Mode analysis
two-component solution accounting for 46.90% variance in the model. The first compo- The L-Mode curve produced appeared quite atypical of a taxonic
nent labeled mistrust comprised six items assessing mistrust in interpersonal relation-
ships including beliefs about others motives. The second component named
or dimensional structure. It was characteristically multimodal with
resentment comprised three items assessing antipathy towards others including emo- the height of the modes decreasing progressively. The form of devia-
tional coldness and hypersensitivity to criticism. tion from prototypical L-Mode curves is likely a result of the indicator
126 A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132

Table 1
Items used, scale location, and endorsement rates.

Construct Scale Endorsed Not-endorsed

Paranoid PD items
Often have to keep an eye out to keep people from using/hurting/lying to you Mistrust 16.40 83.60
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 5.30 94.70
Spend a lot of time wondering if can trust friends/people you work with Mistrust 7.50 92.50
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 2.80 97.20
Find it is best not to let others know much about you because they will use it against it Mistrust 12.10 87.90
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 2.60 97.40
Detect hidden threats or insults in things people say or do Mistrust 6.80 93.20
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 2.50 97.50
The kind of person who takes a long time to forgive people who have insulted/slighted you Resentment 16.90 83.10
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 4.60 95.40
Many people you can't forgive because they said/did something long ago Resentment 8.70 91.30
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 2.90 97.10
Often get angry or lash out when someone criticizes or insults you Resentment 9.40 90.60
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 3.30 96.70
Often suspected that your spouse or partner has been unfaithful Mistrust 8.00 92.00
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 4.50 95.50
When around people, often feel that you are being watched or stared at Mistrust 6.60 93.40
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 1.60 98.40

Schizoid PD items
Are there very few people you're really close to outside of immediate family? Social withdrawal 32.40 67.60
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 1.40 98.60
Would be just happy without having any close relationship Social withdrawal 17.10 82.90
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 0.70 99.30
Take little pleasure in being with others Social withdrawal 8.30 91.70
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 0.70 99.30
Have almost always preferred to do things alone rather than with others. Social withdrawal 15.60 88.40
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 1.50 98.50
Could be content without ever being sexually involved with anyone Social withdrawal 32.00 68.00
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 1.10 98.90
Rarely show much emotion Emotional detachment 17.40 82.60
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 2.00 98.00
Very few things that give you pleasure Emotional detachment 8.20 91.80
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 1.00 99.00
Rarely react to praise or criticism Emotional detachment 13.10 86.90
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 0.90 99.10
The sort of person who doesn't care about what people think about you Social withdrawal 32.50 67.50
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 1.80 98.20
Find nothing makes you happy or sad Emotional detachment 5.60 94.40
Ever trouble you or cause problems at work/school or with family/other people Functional disturbance 0.70 99.30

N = 43,093. Scale locations of study items. All scales except functional disturbance scales are based on PCA with promax rotation.

distribution deviating from a continuous distribution and approxi- 3.2.2. MAXEIG analysis
mating an ordered categorical variable. However, this characteristic MAXEIG produced three curves that appeared to be rising at the
of the data is unlikely to confound the performance of L-Mode high end of the distribution. Although most of the average MAXEIG
when implemented with CCFIs (Ruscio and Walters, 2009). In Fig. 3, curve did not fall within the area bounding the graph from the simu-
the research curve appeared to be more consist with that of the sim- lated dimensional data, it still appears to be rising like the graph from
ulated dimensional data. the simulated dimensional data (Fig. 5). It is also a better fit compared
Applying the multiple hurdles consistency testing approach to to that of the simulated taxonic data, thus supporting a dimensional
evaluating our results, there appears to be greater support for a di- structure.
mensional model. The CCFIs across the three taxometric methods
(0.521, 0.378, and 0.274, respectively) have an average of 0.391. 3.2.3. L-Mode analysis
This just falls outside the dual-threshold range of 0.40 to 0.60 and bet- Similar to paranoid PD indicators, the L-Mode curve produced also
ter supports a dimensional, rather than taxonic structure for paranoid appeared atypical, characteristically multimodal with the height of
PD. the modes decreasing progressively. Notwithstanding, the L-Mode re-
search curve appeared to be a better fit with that of the simulated di-
mensional data (Fig. 6).
3.2. Latent structure of schizoid PD Overall, results appear to converge on a dimensional structure.
The CCFIs produced from the taxometric procedures (0.384, 0.36,
3.2.1. MAMBAC analysis and 0.436, respectively) have an average of 0.368. This falls outside
MAMBAC produced six individual curves; five appeared to be rising the dual threshold of 0.40 to 0.60 and better supports a dimensional
at the high end of the distribution, and one appeared flat. The average rather than taxonic structure for schizoid PD.
curve also appeared to be rising at the high end of the distribution. In The Bayesian probability distributions for paranoid and schizoid
Fig. 4, the average MAMBAC curve superimposed over curves produced PDs (Figs. 7 and 8, respectively) conform to what may be expected
from simulated data suggests a closer fit with the simulated dimension- of a dimensional structure. Probability estimates are converging
al data. around five or six values including 0 and 1 rather than conversing
A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132 127

Categorical Comparison Data Dimensional Comparison Data

0.35
0.35

0.30
0.30

0.25
0.25
Mean Difference

Mean Difference
0.20
0.20

0.15
0.15

0.10
0.10
0.05

0.05
0.00

0.00
0 10000 20000 30000 40000 0 10000 20000 30000 40000

50 Cuts 50 Cuts

Fig. 1. Averaged MAMBAC (all pairs) curve for the paranoid PD indicators juxtaposed over taxonic and dimensional comparison simulations in the left and right panels respectively.
For all figures, darker lines represent the actual data and the lighter lines represent the area bounding the minimum and maximum values of the taxonic and dimensional compar-
ison data. The gray band when visible represents the middle 50% of data points obtained in the simulation.

around 0 and 1 alone, which may have been expected for a taxonic social functioning, role-emotional, and mental health scales. For the di-
construct. mensional model, we summed all the scales into one severity indicator.
For the categorical model, cases were designated based on diagnostic
3.3. Comparative validities of categorical versus dimensional models information contained in the survey (i.e., meeting or not meeting DSM
criteria). There were some missing cases for these analyses for individ-
Next, we examined the comparative validities of categorical and di- uals who did not complete the SF-12v2 scales (327, 323, and 339 cases
mensional models of paranoid and schizoid PDs (Table 2) at predicting respectively). From Table 2, it is clear that the dimensional model

Categorical Comparison Data Dimensional Comparison Data


1.5

1.5
Eigenvalue

Eigenvalue
1.0

1.0
0.5

0.5
0.0

0.0

-0.5 0.0 0.5 1.0 1.5 2.0 2.5 -0.5 0.0 0.5 1.0 1.5 2.0 2.5

100 Windows 100 Windows

Fig. 2. MAXEIG average curve for the paranoid PD indicators juxtaposed over taxonic and dimensional comparison simulations in the left and right panels, respectively.
128 A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132

Categorical Comparison Data Dimensional Comparison Data

6
6

5
5

4
4
Density

Density
3
3

2
2

1
1

0
0

0 2 4 6 0 2 4 6
Factor Scores Factor Scores

Fig. 3. L-Mode curve obtained from the paranoid PD analysis juxtaposed over simulated taxonic and dimensional data in the left and right panels, respectively.

generally outperforms the categorical model at predicting the three dimensional structure for both paranoid and schizoid PDs across the
variables. three taxometric procedures. For both paranoid and schizoid PDs, a di-
mensional model outperformed a categorical model at predicting the
4. Discussion designated external variables — mental health, social, and role-
emotional functioning.
We set out to investigate the latent structure of paranoid and schiz- Our evidence of a dimensional structure for paranoid PD is consis-
oid PDs, two personality disorders that have received little attention tent with similar studies from two prior investigations of the same
from taxometric investigations. We obtained converging evidence of a construct (Arntz et al., 2009; Edens et al., 2009), adding to growing

Categorical Comparison Data Dimensional Comparison Data


0.25
0.25

0.20
0.20
Mean Difference

Mean Difference
0.15
0.15

0.10
0.10

0.05
0.05
0.00

0.00

0 10000 20000 30000 40000 0 10000 20000 30000 40000

50 Cuts 50 Cuts

Fig. 4. Averaged MAMBAC (all pairs) curve for the schizoid PD indicators juxtaposed over taxonic and dimensional comparison simulations in the left and right panels, respectively.
A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132 129

Categorical Comparison Data Dimensional Comparison Data

0.8

0.8
0.6

0.6
Eigenvalue

Eigenvalue
0.4

0.4
0.2
0.2

0.0
0.0

-0.5 0.0 0.5 1.0 1.5 -0.5 0.0 0.5 1.0 1.5
50 Windows 50 Windows

Fig. 5. Averaged MAXEIG curve for the schizoid PD indicators juxtaposed over taxonic and dimensional comparison simulations in the left and right panels, respectively.

support for the dimensionality of this construct. Our study was the factor for schizophrenia spectrum has received consistent support
first to examine the structure of schizoid PD. We were somewhat sur- for a taxonic structure.
prised at our dimensional findings for this construct, given the partial The results of our study should, however, not be regarded as being
overlap of schizoid symptoms with social anhedonia, which has dem- in conflict with numerous taxometric studies supporting a taxonic
onstrated taxonicity in previous studies (Blanchard et al., 2000; structure for schizotypy. It may be that paranoid and schizoid PDs
Horan et al., 2004). Obtaining dimensional evidence for schizoid and possess latent structures dissimilar from schizotypy and schizotypal
paranoid PD is also surprising given their perceived genetic/familial PD because they represent phenomenologically separate entities
relationship with schizophrenia. Further, schizotypy, a vulnerability from the rest of the schizophrenia spectrum. As noted by Edens and

Categorical Comparison Data Dimensional Comparison Data


1.2

1.2
1.0

1.0
0.8

0.8
Density

Density
0.6

0.6
0.4

0.4
0.2

0.2
0.0

0.0

0 2 4 6 8 0 2 4 6 8
Factor Scores Factor Scores

Fig. 6. L-Mode curve obtained from the schizoid PD indicators juxtaposed on simulated taxonic and dimensional comparison data.
130 A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132

DISTRIBUTION OF BAYESIAN PROBABILITIES


35000

Table 2
Predictive validities of categorical and dimensional Models.
30000

External variables Categorical model Dimensional model

Paranoid PD
25000

Norm-based social functioning scale rpb = − 0.15** r = − 0.20**


rpb = − 0.14** r = − 0.18**
Frequency

Norm-based role emotional scale


20000

Norm-based mental health scale rpb = − 0.19** r = − 0.25**


15000

Schizoid PD
Norm-based social functioning scale rpb = − 0.12** r = − 0.16**
10000

Norm-based role emotional scale rpb = − 0.11** r = − 0.13**


Norm-based mental health scale rpb = − 0.14** r = − 0.16**
5000

Categorical model is based on DSM-IV status and the dimensional model is based on
severity scores.
0

Missing cases (n = 327 for norm-based social functioning scale, n = 323 for norm-
0.0 0.2 0.4 0.6 0.8 1.0
based role emotional scale, and n = 339 for norm-based mental health scale).
Prob(Taxon Member)

Fig. 7. Bayesian posterior probability distribution for paranoid PD.

colleagues, this state of affairs may be reflected in the lack of consen- 1998; Kirkpatrick et al., 2002). Recently, Kirkpatrick et al. (2008) de-
sus in studies examining the genetic relationship between schizo- termined that summer birth and male biological sex, critical factors in
phrenia and paranoid PD. In this regard, it may also be useful to the pathogenesis of deficit schizophrenia, were also associated with
consider the indicators that have been used to study schizotypy and schizoid-like features in non-clinical individuals. This state of affairs
schizotypal PD and our indicators for paranoid and schizoid PDs. is also explainable within a threshold model of vulnerability to deficit
The majority of the studies that obtained a taxonic structure for schi- schizophrenia. Similar risk factors are found within deficit schizo-
zotypy drew indicators from Chapman et al. (1976) widely used mea- phrenia and individuals with schizoid features because the distribu-
sure of schizotypy and focused on the Perceptual Aberration, Magical tion of risk is dimensional and additive. At critical levels of other
Ideation, Referential Thinking, Social Anhedonia, and Physical Anhe- vulnerability factors working in tandem with summer birth and
donia subscales. Lenzenweger et al. (2007) obtained taxonic findings male biological sex (e.g., neurocognitive functioning), a likely taxonic
with endophenotypes. Social and Physical Anhedonia scales slightly deficit syndrome emerges (Blanchard et al., 2000; Horan et al., 2004).
overlap with our Social Withdrawal and Emotional Detachment Our dimensional results add to growing taxometric evidence of
scales for schizoid PD but are hardly equivalent. Thus there is no rea- the dimensional structure of most DSM-defined PDs (Haslam, 2003,
son to expect that our results would be congruent with studies using 2007). The study findings support incorporating paranoid and schiz-
those scales as indicators. oid PDs into current research efforts to organize PDs into broad di-
Another possibility is that schizoid and paranoid symptoms do mensions. Tackett et al. (2008) recently demonstrated that the
exist on a dimension of severity and impairment relative to non- application of a five-factor model of personality pathology adequately
pathology. However, in combination with other vulnerability/protec- incorporates Cluster A PDs. They uncovered a “peculiarity” factor cor-
tive and environmental factors (e.g., birth environment), individuals related with “odd/eccentric” features in a sample that included first
scoring high on the paranoid and schizoid PD spectrums diverge degree relatives of individuals with schizophrenia and schizoaffective
into a distinct taxon. This is consistent with multifactorial threshold disorder. Although some researchers have called for a complete over-
models of schizophrenia (e.g., Gottesman and Shields, 1976; McGue haul of the current categorical scheme, taxometrics has not complete-
et al., 1983) that allow for dichotomous outcomes when continuously ly supported dimensionality for all PDs. Indeed more studies support
distributed dispositions reach a critical threshold. Gottesman's model the taxonic status of schizotypal PD although a recent study sug-
incorporates the effects of multiple genes and multiple environmen- gested that it may be dimensional (Rawlings et al., 2008). Our find-
tal factors working in an additive fashion to yield schizophrenia. ings add to growing support for their dimensional representation,
Schizoid features are peculiar in their symptomatic overlap with but the presence of taxonic PD findings may lend better credence to
the deficit subtype of schizophrenia, characterized primarily by social a combination of categorical and dimensional models rather than a
anhedonia, blunted affect, and poverty of speech (Kirkpatrick et al., complete overhaul of a categorical model (Ruscio et al., 2006). More-
over, as Arntz and colleagues contend, a number of other considerations
should factor into decisions to adopt a completely dimensional model.
DISTRIBUTION OF BAYESIAN PROBABILITIES
10000 15000 20000 25000 30000 35000

These include the degree to which diagnostic criteria of individual PDs


are incorporated into studies of normal personality functioning and
the extent to which the broad domains proposed in factor models
truly represent the spectrum of clinical phenomena of interest to
clinicians.
Frequency

4.1. Limitations

The limitations of our study are as follows. One limitation is the


number and scope of the items we used to create candidate indicators,
half of which were items assessing functional problems. This reflects a
5000

limitation of using archived epidemiological data, as the researcher is


often constrained to variables contained in the data. Notwithstanding
0

0.0 0.2 0.4 0.6 0.8 1.0 the few items contained in the survey, DSM diagnostic criteria were
Prob(Taxon Member) assessed for both PDs, increasing confidence in conclusions about
their latent structure. It was the case that the simulated taxonic and
Fig. 8. Bayesian posterior probability distribution for schizoid PD. dimensional comparison curves were often similar, particularly
A.O. Ahmed et al. / Psychiatry Research 196 (2012) 123–132 131

MAMBAC and L-Mode making it difficult to clearly determine latent Conflict of interest
structure by mere visual inspection. This may reflect a limitation in
the indicators — we had only three indicators per construct one of None
which had only four ordered categories. A rejoinder is that Walters
and Ruscio (2009) found that with adequate validities and nuisance
Role of funding source
correlation, indicators with four or more ordered categories distin-
guished with high accuracy.
The reported study was not externally funded or sponsored.
A related issue is the degree to which DSM criteria thoroughly ac-
cess the characteristics of paranoid and schizoid PDs (Arntz et al.,
2009). Current results better support a dimensional structure based Acknowledgment
on DSM criteria; however, it may be that features not included in
DSM criteria such as cognitive style, self-concept, endophenotypes, The authors acknowledge the National Institute of Health and the
or perhaps features specifically shared with schizotypy may reveal a National Institute on Alcohol Abuse and Alcoholism for providing
taxonic structure. Meehl (1989) noted that efforts at studying “schi- access to the NESARC data.
zotaxia” should focus on biological indicators or endophenotypes
given their closeness to genetic causes. He suggested that such indica-
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