DRUGS TO BE AVOIDED BY CONGENITAL LONG QT PATIENTS
CredibleMeds® has reviewed all available evidence and has placed the following drugs in
Generic Name
Abarelix (PR)
Abiraterone (CR)
Aclarubicin (KR)
Albuterol (salbutamol) (SR)
Alfuzosin (PR)
Alimemazine
(Trimeprazine) (PR)
Amantadine (CR)
Amiodarone (KR)
Amisulpride (CR)
Amitriptyline (CR)
Amphetamine
(Amfetamine) (SR)
Amphotericin B (CR)
Amsacrine (Acridinyl
anisidide) (CR)
Anagrelide (KR)
Apalutamide (PR)
Apomorphine (PR)
Arformoterol (SR)
Aripiprazole (PR)
Arsenic trioxide (KR)
Artemether/Lumefantrine
(PR)
Artenimol/piperaquine (PR)
Asenapine (PR)
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designated risk categories for their risk of causing torsades de pointes (TdP): Known Risk
of TdP (KR), Possible Risk of TdP (PR), Conditional Risk of TdP (CR) or Special Risk
(SR). The full description of these categories can be found on the CredibleMeds website.
We recommend that patients with Congenital Long QT Syndrome avoid use of these
medicines if at all possible or take them under close medical observation.
Brand Name Generic Name Brand Name Generic Name Brand Name
Plenaxis Astemizole (KR) Hismanal Cisapride (KR) Propulsid
Zytiga and others Atazanavir (CR) Reyataz and others Citalopram (KR) Celexa and others
Aclacin and others Atomoxetine (PR) Strattera Clarithromycin (KR) Biaxin and others
Proventil and others Zithromax and Clofazimine (PR) Lamprene
Azithromycin (KR)
others
Uroxatral Clomipramine (PR) Anafranil
Bedaquiline (PR) Sirturo
Clotiapine (PR) Entumine
Nedeltran and others
Bendamustine (PR) Treanda and others
Clozapine (PR) Clozaril and others
Symmetrel and others Bendroflumethiazide
Cobimetinib (PR) Cotellic
(Bendrofluazide) Aprinox and others
Cordarone and others
(CR) Cocaine (KR) Cocaine
Solian and others
Benperidol (PR) Anquil and others Crizotinib (PR) Xalkori
Elavil (Discontinued
Bepridil (KR) Vascor Cyamemazine
6/13) and others Tercian
(Cyamepromazine) (PR)
Betrixaban (PR) Bevyxxa
Adderal-XR and others Dabrafenib (PR) Tafinlar
Bortezomib (PR) Velcade and others
Dasatinib (PR) Sprycel
Fungilin and others Bosutinib (PR) Bosulif
Degarelix (PR) Firmagon and others
Buprenorphine (PR) Butrans and others
Amsidine
Delamanid (PR) Deltyba
Cabozantinib (PR) Cometriq
Agrylin and others Desipramine (PR) Pertofrane and others
Capecitabine (PR) Xeloda
Erleada Deutetrabenazine (PR) Austedo
Ceritinib (PR) Zykadia
Apokyn and others Dexmedetomidine (PR) Precedex and others
Aquachloral and
Chloral hydrate (CR)
Brovana others Dexmethylphenidate (SR) Focalin and others
Abilify and others Chloroquine (KR) Aralen Dextroamphetamine
Dexedrine and others
(Dexamfetamine) (SR)
Trisenox Thorazine and
Chlorpromazine (KR)
others Dextromethorphan/Quinidine
Nuedexta
Coartem (PR)
Cilostazol (KR) Pletal
Diphenhydramine (CR) Benadryl and others
Eurartesim Cimetidine (CR) Tagamet and others
Saphris and others Ciprofloxacin (KR) Cipro and others
Generic Name Brand Name Generic Name Brand Name Generic Name Brand Name
Disopyramide (KR) Norpace Formoterol (SR) Foradil and others Leuprolide (Leuprorelin) (PR) Lupron and others
Dobutamine (SR) Dobutrex Furosemide (frusemide) Levalbuterol (Levsalbutamol) (SR) Xopenex and others
Lasix and others
(CR)
Dofetilide (KR) Tikosyn Levofloxacin (KR) Levaquin and others
Galantamine (CR) Reminyl and others
Dolasetron (PR) Anzemet Levomepromazine
Nosinan and others
Garenoxacin (CR) Geninax (Methotrimeprazine) (KR)
Domperidone (KR) Motilium and others
Gatifloxacin (KR) Tequin Levomethadone (levamethadone)
Donepezil (KR) Aricept
(PR)
Gemifloxacin (PR) Factive
Dopamine (SR) Intropine
Levomethadyl acetate (KR) Orlaam
Gilteritinib (PR) Xospata
Doxepin (CR) Sinequan and others
Levosulpiride (KR) Lesuride and others
Glasdegib (PR) Daurismo
Dronedarone (KR) Multaq
Lisdexamfetamine (SR) Vyvanse
Granisetron (PR) Kytril and others
Droperidol (KR) Inapsine and others
Lithium (PR) Eskalith and others
Grepafloxacin (KR) Raxar
Droxidopa (SR) Northera
Lofexidine (PR) Lucemyra
Halofantrine (KR) Halfan
Efavirenz (PR) Sustiva and others
Imodium and many other OTC
Haloperidol (KR) Haldol (US & UK) and others Loperamide (CR)
Eliglustat (PR) Cerdelga and Rx brands
Hydrochlorothiazide (CR) Apo-Hydro and others
Encorafenib (PR) Braftovi Lopinavir/Ritonavir (PR) Kaletra and others
Hydrocodone - ER (PR) Hysinglaâ„¢ ER and others
Entrectinib (PR) Rozlytrek Maprotiline (PR) Ludiomil and others
Hydroquinidine
Eperisone (CR) Myonal and others Serecor Melperone (PR) Bunil and others
(Dihydroquinidine) (KR)
Ephedrine (SR) Rynatuss and others Memantine (PR) Namenda XR and many others
Hydroxychloroquine (KR) Plaquenil and others
Epinephrine (Adrenaline) Mesoridazine (KR) Serentil
Primatene and others Hydroxyzine (CR) Atarax and others
(SR)
Metaproterenol (Orciprenaline)
Ibogaine (KR) None Metaprel and others
Epirubicin (PR) Ellence and others (SR)
Ibutilide (KR) Corvert
Eribulin mesylate (PR) Halaven Methadone (KR) Dolophine and others
Iloperidone (PR) Fanapt and others
Erythromycin (KR) E.E.S. and others Methamphetamine
Desoxyn and others
Imipramine (Melipramine) (Metamfetamine) (SR)
Escitalopram (KR) Cipralex and others Tofranil
(PR)
Methylphenidate (SR) Ritalin and others
Esomeprazole (CR) Nexium and others
Arcapta Neohaler (US) and
Indacaterol (SR) Metoclopramide (CR) Reglan and others
Ezogabine (Retigabine) others
Potiga and others Metolazone (CR) Zytanix and others
(PR)
Indapamide (CR) Lozol and others
Famotidine (CR) Pepcid and others Metronidazole (CR) Flagyl and many others
Inotuzumab ozogamicin
Besponsa
Felbamate (PR) Felbatol (PR) Mianserin (PR) Tolvon

Fenfluramine (SR) Pondimin and others Isoproterenol (SR) Medihaler-Iso and others Midodrine (SR) ProAmatine and others

Fenoterol (SR) Berotec and others Isradipine (PR) Dynacirc Midostaurin (PR) Rydapt

Fingolimod (PR) Gilenya Itraconazole (CR) Sporanox and others Mifepristone (PR) Korlym and others

Flecainide (KR) Tambocor and others Ivabradine (CR) Procoralan and others Mirabegron (PR) Myrbetriq

Fluconazole (KR) Diflucan and others Ivosidenib (PR) Tibsovo Mirtazapine (PR) Remeron

Fluorouracil (5-FU) (PR) Adrucil and others Ketanserin (PR) Sufrexal Moexipril/Hydrochlorothiazide (PR) Uniretic and others

Fluoxetine (CR) Prozac and others Ketoconazole (CR) Nizoral and others Moxifloxacin (KR) Avelox and others

Flupentixol (PR) Depixol and others Lacidipine (PR) Lacipil and others Necitumumab (PR) Portrazza

Fluticasone And Lansoprazole (CR) Prevacid Nelfinavir (CR) Viracept

Advair and others
Salmeterol (SR)
Lapatinib (PR) Tykerb and others Nicardipine (PR) Cardene
Fluvoxamine (CR) Faverin and others
Lefamulin (PR) Xenleta Nifekalant (KR) Shinbit
Lenvatinib (PR) Lenvima Nilotinib (PR) Tasigna

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 Generic Name
Norepinephrine (SR)
Norfloxacin (PR)
Nortriptyline (PR)
Nusinersen (PR)
Ofloxacin (PR)
Olanzapine (CR)
Olodaterol (SR)
Omeprazole (CR)
Ondansetron (KR)
Osimertinib (PR)
Oxaliplatin (KR)
Oxymetazoline (SR)
Oxytocin (PR)
Paliperidone (PR)
Palonosetron (PR)
Panobinostat (PR)
Pantoprazole (CR)
Papaverine HCl (Intra-
coronary) (KR)
Paroxetine (CR)
Pasireotide (PR)
Pazopanib (PR)
Pentamidine (KR)
Perflutren lipid microspheres
(PR)
Perphenazine (PR)
Phentermine (SR)
Phenylephrine (SR)
Phenylpropanolamine (SR)
Pilsicainide (PR)
Pimavanserin (PR)
Pimozide (KR)
Note: Medicines
Pipamperone (PR) on this listDipiperon
regularly and we recommend
Piperacillin/Tazobactam (CR) Tazosyn and Zosyn
on this form.
Pitolisant (Tiprolisant) (PR)
Posaconazole (CR)
Disclaimer and Waiver: The information presented is intended solely for the purpose of providing general information about health-related matters. It is not intended for
any other purpose, including but not limited to medical advice and/or treatment, nor is it intended to substitute for the users
providers. To that extent, by use of this website and the information it contains, the user affirms the understanding of the purpose and releases AZCERT, Inc. from any
claims arising out of his/her use of the website and its lists. The absence of drugs from these lists should not be considered an indication that they are free of risk of QT
prolongation or torsades de pointes. Many medicines have not been tested for this risk in patients, especially those with congenital long QT syndrome.
Brand Name Generic Name Brand Name Generic Name Brand Name
Levophed Pretomanid (PR) none Nolvadex(discontinued 6/13)
Tamoxifen (PR)
and others
Noroxin and others Primaquine phosphate (PR) None found
Telaprevir (CR) Incivo and others
Pamelor and others Probucol (KR) Lorelco
Telavancin (PR) Vibativ
Spinraza Procainamide (KR) Pronestyl and others
Telithromycin (PR) Ketek
Floxin Promethazine (PR) Phenergan
Terbutaline (SR) Brethine and others
Zyprexa and others Propafenone (CR) Rythmol SR and others
Terfenadine (KR) Seldane
Striverdi Respimat Propofol (KR) Diprivan and others
Terlipressin (KR) Teripress and others
Losec and others Prothipendyl (PR) Dominal and others
Terodiline (KR) Micturin and others
Zofran and others Pseudoephedrine (SR) PediaCare and others
Tetrabenazine (PR) Nitoman and others
Tagrisso Quetiapine (CR) Seroquel
Thioridazine (KR) Mellaril and others
Eloxatin Quinidine (KR) Quinaglute and others
Tiapride (PR) Tiapridal and others
Afrin and others Quinine sulfate (CR) Qualaquin
Tipiracil/Trifluridine (PR) Lonsurf
Pitocin and others Ranolazine (CR) Ranexa and others
Tizanidine (PR) Zanaflex and others
Invega and others Ribociclib (PR) Kisqali
Tolterodine (PR) Detrol and others
Aloxi Rilpivirine (PR) Edurant and others
Toremifene (PR) Fareston
Farydak Risperidone (CR) Risperdal
Torsemide (Torasemide) (CR) Demadex and others
Protonix and others Ritodrine (SR) Yutopar
Tramadol (PR) Crispin and others
Romidepsin (PR) Istodax
none
Desyrel (discontinued 6/13)
Roxithromycin (KR) Rulide and others Trazodone (CR)
and others
Paxil and others
Salmeterol (SR) Serevent and others
Trimethoprim and
Signifor Septra and others
Saquinavir (PR) Invirase(combo) Sulfamethoxazole (SR)
Votrient
Sertindole (PR) Serdolect and others Trimipramine (PR) Surmontil and others
Pentam
Sertraline (CR) Zoloft and others Tropisetron (PR) Navoban and others
Definity and others Sevoflurane (KR) Ultane and others Valbenazine (PR) Ingrezza
Sibutramine (SR) Meridia Vandetanib (KR) Caprelsa
Trilafon and others
Siponimod (PR) Mayzent Vardenafil (PR) Levitra
Adipex P and others
Solifenacin (CR) Vesicare Vemurafenib (PR) Zelboraf
Neosynephrine
Sorafenib (PR) Nexavar Venlafaxine (PR) Effexor and others
Acutrim and others
Sotalol (KR) Betapace and others Vilanterol/fluticasone furoate
Sunrythm Breo Ellipta
(SR)
Sparfloxacin (KR) Zagam
Nuplazid
Voriconazole (CR) VFend
Sulpiride (KR) Dogmatil and others
Orap
Vorinostat (PR) Zolinza
Sultopride (KR) Barnetilevidence
and others supports their continued placement on this list. The list changes
are reviewed on an ongoing basis to
(E.U) and others assure that the available Xylometazoline
checking the website at crediblemeds.org for the most up-to-date information. There may be many additional Sinosil and others
Sunitinib (PR) Sutent (Xylomethazoline) (SR) brand names that are not listed
Wakix
Tacrolimus (PR) Prograf and others Ziprasidone (CR) Geodon and others
Noxafil and others Zotepine (PR) Losizopilon and others
Zuclopenthixol (Zuclopentixol)
Cisordinol and others
(PR)relationships with their own health care
Generated: November 5, 2019. List last revised: October 21, 2019