Adult Critical Care IV Medication Infusion Sheet

March 2010
DRUG STD CONC STD DILUTION STD FLUID COMMON ADULT MAX ADMIN. RATE MAX CONC/ Administration
ALT FLUID ADMINISTRATION RATE REFERENCE Central (C) or
3,4
Peripheral (P)
Abciximab 2 mg/mL (bolus) Bolus: 10mg/5mL D5W / NS Bolus: 0.25 mg/kg 10 mcg/min 2 mg/mL C or P
36 mcg/mL 9mg/250mL 0.125 mcg/kg/min x 12 hours Use 0.22 micron filter

Amiodarone 1.5 mg/mL (bolus) Bolus: 150mg/100mL D5W Bolus: 150 mg over 10 min Max dose 2.2g/ 24hr 2 mg/mL C or P:
1.8 mg/mL 450mg/250mL (use non-PVC bag) 1 mg/min x 6 hours (≤ 2 mg/mL)
0.5 mg/min x 18 hours
Argatroban 1 mg/mL 250mg/250mL D5W/NS 2 mcg/kg/min 10 mcg/kg/min 1 mg/mL C or P
Hepatic Failure, Heart Failure,
Multisystem organ failure start at
0.5 – 1 mcg/kg/min
Bivalirudin 5 mg/mL 250mg/50mL D5W/NS Bolus: 0.75mg/kg 2.5mg/kg/hr 5mg/mL
3 C or P
1.75mg/kg/hr
For CrCl < 30mL/min: 1 mg/kg/hr
Bumetanide 0.04 mg/mL 10mg/250mL D5W 0.25 - 0.5 mg/hr 0.25 mg/mL C or P
(undiluted)
Cisatracurium 0.8 mg/mL 200mg/250mL D5W / NS Bolus 0.15 mg/kg IV 2 mg/mL C or P
0.15-0.2 mg/kg/hr
Dexmedetomidine 4 mcg/mL 200mcg/50mL NS 0.2 – 1.4 mcg/kg/hr 4 mcg/mL
3 C or P
Diltiazem 1 mg/mL 100mg/100mL D5W / NS Bolus 0.25 mg/kg over 2 min 15 mg/hr 1 mg/mL C or P
5-15 mg/hr
4
Dobutamine 2 mg/mL 500mg/250mL D5W Premix/ NS 2.5-20 mcg/kg/min 40 mcg/kg/min 12.5 mg/mL C or P

Dopamine 1.6 mg/mL 400mg/250mL D5W Premix/ NS 2-20 mcg/kg/min 20 mcg/kg/min 12.8 mg/mL
4 C: preferred
3.2 mg/mL 800mg/250mL P: large vein
Drotrecogin alfa 0.1 mg/mL 15mg/150mL NS 24 mcg/kg/hr (max 135 kg) Not to exceed 96hrs 0.1 mg/mL C or P
Epinephrine 64 mcg/mL 16mg/250mL D5W / NS 1-10 mcg/min 1 mg/mL
4 C: preferred
128 mcg/mL 32mg/250mL P: large vein
Eptifibatide 2 mg/mL (bolus) Bolus: 20mg/10mL RTU Premix glass vials Bolus: 180 mcg/kg (PCI: bolus x 2) Max bolus: 22.6mg 2 mg/mL C or P
0.75 mg/mL 75mg/100mL 2 mcg/kg/min Max inf: 15 mg/hr
For CrCl < 50 mL/min: 1 mcg/kg/min
Esmolol 10 mg/mL 2500mg/250mL RTU Premix/ D5W Bolus: 500mcg/kg over 1 min 300 mcg/kg/min 40 mg/mL
1 C or
50-300 mcg/kg/min P: (≤ 10 mg/mL)
Esomeprazaole 0.8 mg/mL (bolus) Bolus: 80mg/100mL NS Bolus: 80mg over 30 min C or P
Acute UGI Bleed 0.32 mg/mL 80mg/250mL 8 mg/hr up to 72 hrs
Fentanyl 10 mcg/mL 1000mcg/100mL D5W / NS 25-150 mcg/hr 20 mcg/mL C or P
Furosemide 1 mg/mL 250mg/250mL D5W / NS 10-40 mg/hr 160 mg/hr 10 mg/mL C or P
500mg/250mL
Heparin 100 units/mL 25,000units/250mL D5W Premix/ NS Bolus: 65 unit/kg C or P
13 units/kg/hr
See Heparin Protocol
Insulin 1 unit/mL 100units/100mL NS / D5W See Insulin Protocol Titrate to target serum C or P
glucose level

Isoproterenol 16 mcg/mL 4mg/250mL D5W / NS 0.5-20 mcg/min 0.1 mcg/kg/min 16 mcg/mL C or P

Ketamine 1 mg/mL 500mg/500mL NS 8 - 25 mg/hr C or P
Labetalol 2 mg/mL 500mg/250mL D5W / NS 1-2 mg/min C or P
 Adult Critical Care IV Medication Infusion Sheet
March 2010
DRUG STD CONC STD DILUTION STD FLUID COMMON ADULT MAX ADMIN. RATE MAX CONC/ Administration
ALT FLUID ADMINISTRATION RATE REFERENCE Central (C) or
3,4
Peripheral (P)
4
Lidocaine 4 mg/mL 1000mg/250mL D5W Premix / NS 1-4 mg/min 5 mg/min 16 mg/mL C or P

1,3
Lorazepam 0.2 mg/mL 24mg/120mL D5W/NS 0.5-2 mg /hr 8 mg/hr 1 mg/mL C or P
Midazolam 1 mg/mL 50mg/50mL D5W / NS 2-4 mg/hr 20 mg/hr 2 mg/mL C or P
100mg/100mL
2
Milrinone 200 mcg/mL 20mg/100mL D5W / NS Bolus: 50mcg/kg over 10min 1 mcg/kg/min 200mcg/mL C or P
0.375-0.75 mcg/kg/min
2
Morphine 1 mg/mL 50mg/50mL D5W / NS 1-10 mg/hr 5mg/mL C or P
100mg/100mL
3
Nesiritide 6 mcg/mL 1.5mg/250mL D5W / NS Bolus: 2mcg/kg 0.03 mcg/kg/min 6 mcg/mL C or P
0.01 mcg/kg/min
Nicardipine 0.1 mg/mL 25mg/250mL D5W / NS 5 mg/hr 15 mg/hr 0.1 mg/mL C or P*
Titrate by 2.5 mg/hr q15min * site change q12
Nitroglycerin 0.2 mg/mL 50mg/250mL D5W Premix/ NS 5-25 mcg/min 300 mcg/min 0.8 mg/mL C or P
2
0.4 mg/mL 100mg/250mL GLASS
Nitroprusside 0.2 mg/mL 50mg/250mL D5W / NS 0.5-8 mcg/kg/min 10 mcg/kg/min 0.8 mg/mL C or P
0.4 mg/mL Protect from light
Norepinephrine 32 mcg/mL 8mg/250mL D5W / NS 0.5 - 30 mcg/min 1 mcg/kg/min 128 mcg/mL C: preferred
64 mcg/mL 16mg/250mL P: large vein
Octreotide 5 mcg/mL 500mcg/100mL NS / D5W 50-100 mcg/hr 10 mcg/mL C or P
Pentobarbital 1 mg/mL 500mg/500mL D5W/NS Bolus: 10-15 mg/kg over 1-2hrs Goal level 20-40 8 mg/mL C: preferred
0.5-4 mg/kg/hr mcg/mL P: large vein
4
Phenylephrine 400 mcg/mL 100mg/250mL D5W / NS 100-180 mcg/min 400mcg/min 6.4mg/mL C: preferred
P: large vein
Procainamide 4 mg/mL 1000mg/250mL NS Bolus: 15-18mg/kg over 30 min 16 mg/mL C or P
Protect from light 1-4 mg/min
Propofol 10 mg/mL 1000mg/100mL 10% Intralipid Premix 5-75 mcg/kg/min 75 mcg/kg/min 10 mg/mL C or P
Change tubing q12
Rocuronium 5 mg/mL 500mg/100mL D5W Bolus: 0.6 mg/kg C or P
0.6 - 0.9 mg/kg/hr
Sodium Bicarbonate 0.15 mEq/mL 150meq/1000mL D5W 0.15 mEq/mL C: preferred
0.6 mEq/mL 300meq/500mL P: large vein
Vasopressin 0.4 unit/mL 20units/50mL NS/ D5W 0.04 units/min 0.04 units/min 1 unit/mL C
5

Septic Shock
Vasopressin Variceal 0.4 unit/mL 100units/250mL NS/ D5W Bolus: 20 units 0.9 units/min 1 unit/mL C
Bleed 0.2-0.4 units/min
Vecuronium 1 mg/mL 100mg/100mL D5W / NS Bolus: 0.1 mg/kg 1 mg/mL C or P
0.08-0.1 mg/kg/hr

To review clinical care guideline G-13.6ADULT CRITICAL CARE MEDICATIONS FOR CONTINUOUS IV INFUSION