CHAPTER

DRUG STUDY

NAME OF DRUG MECHANISM OF ACTION INDICATION SIDE EFFECT NURSING IMPLICATIONS

DRUG NAME: Effective against Treatment of Eye stinging,  Use a single-

Erythromycin gonorrhea and superficial ocular burning sensation dose
Ophthalmic ointment chlamydia. infections caused application
Erythromycin also tube.
by susceptible
GENERIC NAME: has actions that  After gently
Erythromycin make it useful strains of
pulling down on
outside of the microorganisms; a newborn’s
BRAND NAME: infectious disease prophylaxis of lower eyelid,
Erycortin field. It mimics the ophthalmia extrude a line
effects of the neonatorum caused of ointment the
DOSAGE: gastrointestinal by gonorrhoeae or length of the
About 1 cm polypeptide motilin trachomatis. lower eyelid
on gastrointestinal from the inner
ROUTE: motility. canthus
Ophthalmic The physiologic CONTRAINDICATION: ADVERSE EFFECT: outward.
action produced is Antibiotic therapy Blurred vision  Discard any
FREQUENCY: an increased in can result in remaining
Up to 6 times daily motility during the superinfection or ointment to
depending on interdigestive suprainfection with prevent its
severity of period, without non-susceptible being used
infection affecting organisms. again
posprandial Overgrowth of  Close the
motility. candida can occur child’s eyes
Erythromycin does with erythromycin and count to
not affect either therapy. Patients about 5.
dopamine receptors should be monitored  Wipe away any
or increase closely during excess ointment
acetylcholine therapy. from the
concentration in the child’s face.
gut. Tachyphylaxis  If desired,
can result from delay
motilin receptor application for
downregulation. an hour after
birth to allow
the infant to
view his or her
parents for the
first time with
the clearest
vision
possible.
 NAME OF DRUG MECHANISM OF ACTION INDICATION SIDE EFFECT NURSING IMPLICATIONS

DRUG NAME: Promotes hepatic Prevention treatment Flushing, pain and  Anticipate the
Vitamin K formation of of hemorrhagic swelling at need for
coagulation factors states in neonates. injection site. injection
GENERIC NAME: II, VII, IX, X. immediately
Phytomenadione Essential for normal after birth
clotting of blood.  Administer IM
BRAND NAME: Readily absorbed injection into
Phytomen from GI tract after CONTRAINDICATION: ADVERSE EFFECT: large muscle,
IM. Dyspnea, cyanosis, such as the
DOSAGE: anaphylactic shock anterolateral
1.0 ml muscle of a
newborn’s thigh
ROUTE:  If giving for
IM treatment,
obtain
FREQUENCY: prothrombin
Once immediately time before
after birth within administration
24 hours (the single
best indicator
of vitamin K-
dependent
clotting
factors
 Assess for
signs of
bleeding, such
as black, tarry
stools
(different from
meconium
stools, which
have a greenish
shade],
hematuria
decreased
hemoglobin and
hematocrit
levels, and
bleeding from
any open wounds
or base of the
cord. (These
signs would
indicate that
more vitamin K
is necessary,
because
bleeding
control has not
been achieved.}
 NAME OF DRUG MECHANISM OF ACTION INDICATION SIDE EFFECT NURSING IMPLICATION

DRUG NAME: Many epidemiological Immunization against Local reactions such  As with all
Hepatitis B studies indicate infection caused by as erythema, pain, biologicals,
that patient who known subtypes of swelling or minor epinephrine
GENERIC NAME: develop anti- hepatitis B virus. fever may occur should always
Hepavax- Gene hepatitis B surface rarely. be readily
TF antigen antibodies available for
following infection CONTRAINDICATION: ADVERSE EFFECT: immediate use
BRAND NAME: with hepatitis B are Do not administer in Hyperthermia in case of a
Euvax B immune to the virus the gluteal region & (>38.8oC); systemic rare
upon reexposure. it must not be reactions e.g anaphylactic
DOSAGE: Active immunization administered IV. malaise, asthenia, reaction
0.5 ml with hepatitis B headache, nausea,
vaccine stimulates vomiting, dizziness,
ROUTE: the immune system to myalgia or
IM produce anti-HB’s arthritis; skin rash
without exposing the and transient
FREQUENCY: patient to the risks increase of
3 doses (1st: at of active infection. transaminases.
birth 2nd Infection with
hepatitis D can
occur only with
infection, so
vaccination with
recombinant
hepatitis B vaccine
provides protection
against hepatitis D
as well.
 NAME OF DRUG MECHANISM OF ACTION INDICATION SIDE EFFECT NURSING IMPLICATIONS

DRUG NAME: Live BCG vaccine is Active immunization Rash, injection site  Assess client
BCG an attenuated strain or prevention of TB. reaction, fever, for allergic
of bacillus infection reactions
GENERIC NAME: Calmette-Guerin;  Assess client
Bacillus Calmette- used for active CONTRAINDICATION: ADVERSE EFFECT: with
Guerin immunization against Serious illness or Swelling at site compromised
tuberculosis. high fever, developing to a immune system
BRAND NAME: malnutrition small vesicle and such as those
Japan BCG Vaccine progressive then ulcer in 2-4 who are
dermatitis, serious days infected with
DOSAGE: heart, kidney or HIV/AIDs
0. 05 ml liver disease,  Assess clients
serious cell- for common side
ROUTE: mediated immune effects
Intradermal deficiency. Children
with AIDS
FREQUENCY:
Once after delivery