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Laboratory Tests used in Definition

Hematology
White Blood Cell Count (WBC ct.) The number of white cell counted in 1 liter of
whole blood
Red Blood Cell Count (RBC ct.) The number of red cell counted in 1 liter of
whole blood
Hemoglobin Level Determination (Hgb) Test used to diagnose and follow the treatment
of anemia

Hematocrit (Hct) Packed red cell volume expressed as a


percentage of the total whole blood volume
Mean Corpuscular Volume (MCV) The average volume of an erythrocyte
Mean Corpuscular Hemoglobin (MCH) Average weight (content) of haemoglobin in an
average erythrocyte; directly proportional to the
amount of haemoglobin and the size of the
erythrocyte
Mean Corpuscular Hemoglobin Average concentration of haemoglobin per unit
Concentration (MCHC) volume of erythrocyte; also defined as the ratio
of the weight of haemoglobin to the volume of
erythrocytes
Erythrocyte Sedimentation Rate (ESR) Measures the rate of settling of erythrocytes in
diluted human plasma
Prothrombin Time (PT) A screening test in the diagnosis of coagulation
deficiencies; the length of time required to form
a fibrin clot is measured in seconds

Activated Partial Thromboplastin Time A procedure that measures the time required to
(aPTT) generate thrombin and fibrin polymers via
intrinsic pathway

Reference: Turgeon, Mary Louise Clinical Hematology: Theory and Procedures 5th edition 2012
Brown, Barbara A. Hematology: Principles and Procedures 6th edition 1993
Laboratory Tests used in Clinical Definition
Chemistry
Blood Urea Nitrogen (BUN) Major excretory product of protein metabolism;
used to evaluate renal function; aid in diagnosis
of renal disease

Blood Uric acid (BUA) The product of catabolism of purine nucleic


acids; measured to confirm diagnosis and
monitor treatment of gout

High Density Lipoprotein (HDL) Smallest and most dense lipoprotein particle,
synthesized in both liver and in the intestine
Low Density Lipoprotein (LDL) Consequences of lipolysis of VLDL (Very Low
Density Lipoprotein)
Creatinine Kinase (CK) Physiologic function occurs in muscle cells
Lactate Dehydrogenase (LDH) An enzyme that catalyzes the interconversion of
lactic acid and pyruvic acids

Alanine aminotransferase (SGPT) Liver-specific enzyme; evaluation of hepatic


disorders

Aspartate aminotransferase (SGOT) Highest concentration are found in cardiac


tissue, liver and skeletal muscle; evaluation of
hepatocellular disorder and skeletal muscle
involvement

Alkaline phosphatase (ALP) Most diagnostic significance in the evaluation of


hepatobilliary and bone disorders

Reference:
Bishop, Michael L., et al. Clinical Chemistry: Principles, Techniques and Correlations 7th edition
Laboratory Tests used in Serology- Definition
Immunology
Anti-HAV Antibody to Hepatitis A virus

Anti-HBc Antibody to Hepatitis B core antigen


Anti-HBe Antibody to Hepatitis B core antigen

Anti-HBs Antibody to Hepatitis B surface antigen


Anti-Streptolysin O (ASO) Test A test used to detect the presence of an
antibody produced against streptolysin O- a
hemolysin produced by Streptococci group A
Direct Antiglobulin Test (DAT) A test performed to detect the coating of
erythrocytes with antibodies
Enzyme-linked Immunosorbent Assay A quantitative method of laboratory analysis;
(ELISA) antigen or antibody can be measured using
enzyme-labeled antibody or antigen bound to a
solid support
Indirect Flourescent Assay (IFA) Procedure used to detect homogenous antigen
plus antigen with ntiimmunoglobulins using
fluorescent microscopy

Polymerase Chain Reaction (PCR) A molecular biology technique that uses


amplification of low levels of specific DNA
sequences in a sample to reach the threshold of
detection

Radioimmunoassay (RIA) A laboratory technique using radioactive


substances to evaluate immunoglobulins

Rapid Plasma Reagin (RPR) A serologic test for Venereal disease (syphilis)

Reference: Turgeon, Mary Louise Immunology and Serology in Laboratory Medicine 5th edition, 2014

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