GRAM ( + ) COCCI

REFER TO NOTES
Microbes Characteristics Types and Isolation VF / MOA Sign and symptoms TXT / DOC
STAPHYLOCOCCUS  Pathogenic S. Aureus Lipase : boils , furuncle , Staphylococcal PCN
enzyme carbuncle
MRSA : Vancomycin
Exfoliation : scaleded
skin URSA : Streptogramins
/ Linezolid
Enterotoxin : food
poisoning
S.Epidermidis Bacterial endocarditis in
-NF in skin pt. w/ prosthetic heart
valve (post op )
S. Saprophyticus UTI females
STREPTOCOCCUS S.Pneumonia VF : capsule ,IgA Most common cause of 2nd gen ceph +
Protease CAP extended macrolides

Otitis PCN , Amox

Meningitis in >40 y/o 3rd gen ceph
Viridance strep. Bacterial endocarditis in
-NF in oral cavity pt. w/ prosthetic heart
valve (after dental
trauma)
S. Pyogenes SUPPURATIVE
 rest tract
exudative
pharyngitis PCN derivatives
(strep. throat)
 skin : impetigo
(honey crystal
lesion)
 NON SUPPURATIVE
 scarlet feve
 second d/s Immuno suppressants ,
 fever sand paper Immuno globulin
rash replacemnets /
 strawberry corticosteroids
tongue
S. Agalactae Neonatal meningitis and Ampicillin +
NF of vagina sepsis gentamycin
GRAM (-) COCCUS
NEISSERIA  Kidney shape ISOLATION :
 Diplicocci
Note :  + catalase I sterile specimen
 + oxidase -Chocolate agar plate
N.gonorrhea = (CAP)
glucose only +black colonies

N. meningitides II non sterile

= glucose and specimen
maltose -Thayer martin
medium (CAP+VCN)
Vancomycin
Colistin
Nystatin
-Modified Thayer
Martin
(CAP+VCN+trimetho
prim)

N. gonorrhea VF : GENITAL GONORRHEA Ceftriaxone IM single

-pili Male : dose + Doxycycline X 7
-B-lactamase urethritis , dysuria , days ( chlamydia)
-Ig A protease penile discharge
-Lipo Female : Asymptomatic
 Oligosaccharide ,pelvic inflammatory d/s

OPTHALMIA
NENONATORUM Old : AgNO3
New : Erythromycin
oint.
DISSEMINATE
GONORHEA Ampicillin +
Arthritis , Dermatitis Gentamicin

N. meningitis VF : A .Meningitis 5-40 y/o 3rd gen

-Ig A Protease Cephalosposrins
-Lipo
Oligosaccharide B. Meningococcemia Prop: Rifampicin
(very potent ) -thrombosis (petechial , DOC: PCN ,
-Capsule rash, ecchymoses) Chloramphenicol
-disseminated
intravascular coagulation
(bleeding)
-fried chicken
syndrome/power house
-shock = death

GRAM (-) COCCCOBACILLI

HAEMOPHILUS  Blood loving ISOLATION : CAP

H. Influenza VF : Ig protease Most common cause of 2nd gen ceph +

(pfeiffers Bacillus) CAP extended macrolides
S.pneumonia
H. Influenzae Amoxicillin
Neisseria sp. Otitis Media

: Capsule type
 B Meningitis NOTE :
2mos.- 5y/o VACCINATED :
AMPICILLIN
UNVACCINATED :
AMOXICILLIN
H. Aegypticus Purulent conjunctivitis NA sulfacetamide
-Koch weeks bacillus
H. Ducreyi Chancroid : soft painful
chancre

*if hard T.pallidum

/syphilis
BORDETELLA  gram - B. Pertusis VF : pertussis Pertussis /Whooping Prev. : DPT
toxin cough DOC : Erythromycin
ISOLATION lymphocytosis
-Bordetgengou
media
(potato blood
glycerol agar )
BRUCELLA  common spp. B. Abostus “Bruce cow “ Tetracycline+gentamyc
And reservoir Reservior : COW in
Fatal protein :
MANNER OF erythriol
TRANSMISSION Brecellosis/un
*Direct contact B. Melitensis Sheep Goat dulant
Veterinarian, fever/bangs
slaughter house d/s
*Ingestion
unpasteurized dairy
B. Suis Pigs
B.Canis Dogs
FRANCISCELLA MANNER OF F.Tularensis Tularemia Streptomycin
TRANSMISSION
-bite of ticks/contact Grandular fever :
 with rabbits / rabbit -lympadenopathy LAD
fever Oculograndular fever :
-conjunctivitid +LAD

Ulcerograndular fever : Gi
ulcer + LAD
PASTUERELLA P. multocida Dog or rat disease PCN G
BASTONELLA B.Bacilliforms MOT : bite of Carrions d/s
phlebotomus
sand fly *1st stage :
- oroya fever
-acute hematic phase
-serious infectious
anemia

2nd stage :
-wart like verruca
pervana
-chronic eruptive stage
-benign warty skin
eruptions
B. Quintana Trench fever/five
daTrench fever/five day
B. Henselae Cats scratch d/s Aminoglycosides and
erythromycin
ENTEROBACTERIACE
AE
 facultative
anaerobes
 - oxidase
 Motile
*except Shigella
Klebsiella Yersinia
 Rapid lactose
fermenters
Klebsiella
Escherichia
Enterobacter

Late lactose
fermenters
Citrobacter ,
Serratia,arizonae ,
sonnie ,
enterocolitica

Non lactose
fermenters
Salmonella , shigella ,
Yersinia

Oppotunistic
Proteus
Edwardsiella
Morganella
Providencia

H2S Producing
SPaCEd
Salmonella
Proteus
a-------
Citrobacter freundii
Edwarsiella
d
KLEBSIELLA K.Pneumonia VF:capsule Friendlanders bacillus 2nd gen ceph + ext.
CAP macrolides
ESCHERIACIA  Most aerobic E.coli Indicator : fecal UTI Nitofurantoin
flora of colon (Colon bacillus) contamination of Fluoroquinolones
 Most water DIARRHEAL STAIN
common ETEC (toxigenic)
anerobic + metallic sheet , -travellers
(fusobacterium , green EPEC (pathogenic)
bacteroides) -infantile diarrhea
EHEC (hemorrhage)
*produces shiga like toxic
-hemolytic urimic Fluoroquinolon
NOTE : syndrome HUS es & fluid
 Renal failure
EO157: H7 replacement
 Anemia
Most virulent  thrombocytopenia
factor of EHEC EIEC (invasive)
hamburger *produces shigella like
dysentery
EAEC (aggregative)
-persistent H2O diarrhea
SALMONELLA S.Thyphii Persistent high fever Ciprofloxacin or
(INVASIVE) ceftriaxone
a. enterocolitis
salmonella invasive
b. bacteremia
differentiate it from
shigella non invasive
c. enteric
fever/thphoid
fever
persistent high
fevergrade fever, rose
spot (rare), carrier : gall
bladder
SHIGELLA MEMBERS VF: shigellosis/bacillary
(NON INVASIVE) S. dysenteriae Shiga toxin dysentery
-grp A -neuro toxin
-most virulent factor (seizure)
-cytotoxic
S.Flexneri enterotoxic
-grp B
-common ph ** reason for
dysentery &
S.Boydii tenesmus
-grp C

S. Sonnie
-grp D
-Late lactose
-Self limiting
- no diarrhea effect
-severe cases
*give ciprofloxacin
YERSINIA Y.enterocolitica Enterocolitis
Y. Pestis MOT : “ yeye the Bubonic Plague Aminoglycosides
rat “ and thick - enlarged
bite suppurative lymp
nodes in
groin/axilla called
: buboes
Systemic
- Hemmorrhage &
Necrosis or black
death ( part ng
necrosis na nag
ddark na)
Pneumonic Plague
-Airborne/septic emboli