DRUG STUDY

NAME AND DOSE, MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING

CLASSIFICATION FREQUENCY ACTION S EFFECT RESPONSIBILITY
OF DRUG ROUTE,
DURATION OF
ADMINISTRATION
 Capsules  Reduces gastric  Gastroesophag  Long-term use for CNS: dizziness, ● Assess vital signs.
Generic Name: (delayed- acid secretion eal reflux gastroesophageal headache, ● Check for abdominal pain,
Omeprazole release): 40 mg and increases disease reflux disease, asthenia emesis, diarrhea, or
Brand Name: P.O , daily for gastric mucus  Erosive duodenal ulcers GI: nausea, constipation.
2 weeks and bicarbonate esophagitis vomiting, ● Evaluate fluid intake and
Classification: production,  Short-term diarrhea, output.
Pharmacologic class: creating treatment of constipation, ● Watch for elevated liver
Proton pump protective active abdominal pain function test results (rare).
inhibitor coating on duodenal ulcer Metabolic: ● Tell patient to take 30 to 60
Therapeutic class: gastric mucosa  To reduce risk hypomagnesemi minutes before a meal,
Antiulcer drug and easing of duodenal a preferably in morning.
discomfort from ulcers caused Musculoskeletal ● Instruct patient to swallow
excess gastric by : back pain; capsulesor tablets whole and
acid. Helicobacter fractures of hip, not to chew or crush them. If
pylori wrist, spine he can’t swallow capsule, tell
(with long-term him he may open it, carefully
daily use) sprinkle and mix entire
Respiratory: contents into 1 tbsp of cool
cough, upper applesauce, and swallow
respiratory tract immediately with glass of
infection water.
Skin: rash

●Monitor consistency of the

stool

Probiotics are
Generic Name: Capsule 1 cap P.O. Helps restore intestinal Promotion of general Use is also not advised in considered to be
Gastro Flora daily microflora with good wellness and normal patients at risk of relatively safe.
Probiotics bacteria to maintain intestinal function. opportunistic infections Studies using
normal GUT health. and in those with badly probiotics have
Classification: damaged GI tracts. reported
Supplement/Adjunctiv abdominal
e therapy cramping,
nausea, fever,
soft stools,
flatulence, and
taste ● Assess vital signs.
disturbances.

Significant: Throm
Generic Name: Mild to moderate pain Hypersensitivity. Severe bocytopenia,
Pacetamol  Tablet 500 mg P.O.4- and fever hepatic impairment or leucopenia,
6 hourly active liver disease (IV). neutropenia,
Classification: pancytopenia,
Analgesics (Non- methaemoglobinae
Opioid) & mia,
Antipyretics agranulocytosis,
angioedema, pain
and burning
sensation at inj site.
Rarely, hypotension
and tachycardia.
Gastrointestinal
disorders: Nausea,
vomiting,
constipation.
Nervous system
disorders: Headach
e.
 Psychiatric
disorders: Insomnia
.
Skin and
subcutaneous tissue
disorders: Erythem ●Assess vital signs and
a, flushing, pruritus. neurologic,
cardiovascular,and respiratory
status.
Generic Name: Tablet 0.4 mg  Acts as  Excessive GI ● Hypersensitivity to ● Monitor patient for urinary
Hyoscine-N- P.O.daily for a week competitive motility and scopolamine, other hesitancy or retention.
butylbromide inhibitor at hypertonia in belladonna alkaloids,or
Brand Name: postganglionic irritable bowel barbiturates ●As appropriate,review all
Buscopan muscarinic syndrome,mild ●Obstructive GI disease other significant adverse
receptor sites of dysentery,diver (including paralytic ileus reactions and
Classification: parasympathetic ticulitis,pyloro and intestinal atony) interactions,especially those
Pharmacologic class: nervous system spasm ● Ulcerative colitis or toxic related to the drugs,herbs,and
Antimuscarinic, and on smooth megacolon behaviors mentioned above.
belladonna alkaloid muscles that
Therapeutic class: respond to
Antiemetic,antivertigo acetylcholine
agent,anticholinergic but lack
cholinergic
innervation.Ma
y block
cholinergic
transmission
from vestibular
nuclei to higher
CNS centers ● Advise patient to report
and from fever, sore throat,bleeding,or
reticular bruising.
formation to ● Advise patient to take drug
 vomiting center. with food if it causes GI
upset.However,instruct him to
Disturbs DNA CNS: take extended-release tablets 1
Generic Name: Tablets: 500 mg Po , synthesis in susceptible  Amebiasis ● Heart rate below 45 drowsiness,dizzines hour before or 2 hours after
Metronidazole daily bacterial organisms  Bacterial beats/minute, s,confusion, meals
Brand Name: infections second- or third-degree restlessness,fatigue
Flagyl IV heart block, CV:
Classification: significant first-degree tachycardia,palpitat
Pharmacologic class: heart block; systolic ions,hypotension,tr
Nitroimidazole pressure below 100 mm ansient heart rate
derivative Hg; or changes EENT:
Therapeutic moderate-to-severe cardiac blurred
class:Anti-infective, failure vision,mydriasis,ph
antiprotozoal otophobia,conjuncti
vitis GI:
constipation,dry ●Monitor consistency of the
mouth GU: urinary stool
hesitancy or ● Evaluate fluid intake and
retention Skin: output.
decreased
sweating,rash

Generic Name: a prodrug of thiorphan, CNS:

Racecadotril 100 mg P.O. for 7 an enkephalinase  Acute diarrhea Significant: Angioedema. dizziness,headache,
days until 2 formed inhibitor. It achieves its Respiratory, thoracic and ataxia,vertigo,incoo
Brand Name: stool is recorded antisecretory effect by mediastinal rdination,insomnia,
Hidrasec protecting enkephalins disorders:  Tonsillitis. EENT:
from enzymatic Skin and subcutaneous rhinitis,sinusitis,pha
Classification: degradation thereby tissue disorders: Rash, ryngitis
Antidirrheals prolonging their action erythema, urticaria, GI:
at enkephalinergic erythema multiforme, nausea,vomiting,dia
synapses in the small nodular erythema, papular rrhea,abdominal
intestine and reducing rash, prurigo, pruritus. pain,furry
hypersecretion. Potentially Fatal: Skin tongue,glossitis, dry
reactions. mouth,anorexia
GU: dysuria,dark
urine,incontinence
Hematologic:
leukopenia
Skin:
rash,urticaria,burni
ng,mild skin
dryness,skin
irritation,transient
redness (with
topical forms)