Experiment 1

Name :- Jaideep Kulkarni

Roll No :- 46
GR No:- 1710844
Aim:
To review synthesis methods of metal and metal oxide nanoparticles; and
applications of nanotechnology in healthcare.

Synthesis of metal and metal oxide nanoparticles (Zinc):

Sr. Method of Precursor Characterizatio Stabilizing Conclusions/Result
no Synthesis n techniques agent/Capping s
. agent
1 Whey Zn(NO3)2.6H2 XRD, TEM, Citric acid ZnO nanoparticles
assisted sol- O Raman size 18-89 nm.
gel method Spectroscopy, Absorbance at 315-
UV-Vis 340nm.
Crystalline.
2 Green Zn(NO3)2.6H2 FTIR, TEM, Punicagranatu 10-30 nm ZnO
Synthesis O FESEM, XRD m leaf extract particle size.
as reducing Potential for
agent photocatalytic
degradation.
3 Reduction ZnO UV-Vis, XRD, Cinnamon as 340 nm absorbance
method EDX, SEM capping agent of Zn Nps
Hexagonal wurtzite
4 Homogenou ZnCl2 and FTIR, SEM, 1)1,2 ethane- Absorbance 315-
s phase NaOH TEM, BET diol 400 nm
reaction 2)2-propanol Zn nanoparticles
5 Laser ZnO plates TEM, XRD, Aq. Starch Smaller
ablation FTIR nanoparticles as
compared to
distilled water.
Applications in
biomedical sector.
Applications of Nanotechnology in healthcare (Literature survey):
Sr no. Diseases Nanoparticles Safety issues/ Advantages of
cured/Applications used limits using
nanoparticles
1 Sunscreen TiO2 1.Upto 25% Spread ability
TiO2permitted. improves.
2.Size>100 nm
2 Cancer cell Carbon - Early stage
detection in blood nanotubes detection
stream
3 Detection of Gold nanorods - Shift in colour
Kidney damage due to presence
of proteins
which indicates
damage
4 Drug delivery Gold 1.Gold: Long
nanoparticles size>100 nm circulatory
and Liposomes 2.Liposomes: targeted
size = 50-200 delivery
nm possible
5 Tumor Iron 100-400 nm Solid dosage
nanoparticles through nano-
capsulation
6 Antibacterial and Silver 1.Highest Better uptake of
antifungal nanoparticles toxicity above Ag
medicines 25 ppm. nanoparticles
2.Protein by cells as
denaturation at compared to
high micro size
concentration. particles.
3.Mitochondrial
disfunctioning.
7 Cosmetics ZnO, Ag Size: 60-120 Cosmetic
nanoparticles nm creams are
If liposome transparent and
covering is nearly invisible
absent it can and better
cause side screening in
effects case of
 sunscreens.
8 Imaging Silver and Iron - Increases
oxide efficiency of
nanoparticles MRI,
Ultrasound and
Optical
scanners.

9 Capsules or matrix Polymeric nano - To maintain

particles delivery
therapeutic
level of drug
10 They are used in Quantum dots - In biological
computic , material
photovoltalic
devices