Name: _______________________

It’s Not You It’s Me:

Date: ________________________
Cells Splitting
Pd. _______

1. Go to the following website: https://www.hhmi.org/biointeractive/eukaryotic-cell-cycle-

and-cancer
2. Click on LAUNCH INTERACTIVE
3. Read through the BACKGROUND and answer the associated questions.
4. After the background, each phase of the cell cycle can be clicked to view further
information.

1. Why does cell division remain important to an adult organism even after it is fully
developed?

2. Cells divide, differentiate, or die. What is differentiation?

3. What is apoptosis? What is its purpose?

4. What happens if cell cycle regulators don’t function properly?

5. CELL CYCLE (fill in the table below)

Phase What Happens? Checkpoint

G1

G0 N/A

G2

M
CELL CYCLE REGULATORS AND CANCER
6. What are cell cycle regulators? Include two examples.

7. Cancer is the result of an incorrectly controlled cell cycle. Describe two reasons why cells
can form tumors.

8. Normally, tumor suppressor genes slow down the cell cycle. How do mutated tumor
suppressor genes affect the cell cycle?

During your cell cycle simulation, you had time to think about your choices and were able
to make changes. Cancer cells are abnormal cells that have uncontrolled cell division.

9. How can you tell if a cell is cancerous? Use 2 pieces of evidence in your answer.

10.What are the normal steps in the cell cycle? Describe what happens at each step.

11.Describe 3 ways how changes in the cell cycle and lead to cancer cells.