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Scientists have been attempting for years to learn who may get Alzheimer’s disease. If
the condition could be identified before its worst signs appear, people might get at least
temporary medical help. There is no cure for Alzheimer’s, which steals people’s ability
to care for themselves. But treatment can slow its progress.

The most widely held belief about the cause of Alzheimer’s is that a protein, beta-
amyloid, builds up in patients’ brains. Large amounts of this protein may destroy a
person’s ability to think.

Some scientists question whether beta-amyloid causes Alzheimer’s disease. They think
that the protein build-up may result from it. But most researchers say thick tangles or
plaques of the protein are responsible for the condition. Plaques are unusual groups of
proteins. The researchers say beta-amyloid destroys communication links in the brain.

Among older people, Alzheimer’s is the most common form of dementia, the loss of
abilities needed for normal life. Other mental conditions may seem like Alzheimer’s.
Those conditions need medical treatment that is different from treatment for
Alzheimer’s. A correct diagnosis, or identification, is important.

The best way to diagnose the disease has been a medical examination of the brain after
a person dies. Doctors say that methods to test the living have some problems, like high
costs for widespread use. Public and medical demand for a better way has been
strong. Scientists have been working to produce a dependable test for the disease in
the living.

Match the beginning of phrase and the ending (based on the text info)

It’s difficult to… …clusters(collections) of proteins

There is no… …make thinking process difficult

The cause of Alzheimer is mostly… …Alzheimer with other mental disease

It’s easy to confuse… …diagnose Alzheimer

Protein can… …cure for Alzheimer


Listen to audio script (3:03-4:56), and match words you’ve heard:

Magnetic resonance imaging Beta-amyloid


Radioactive coloring agent Hormones
Florbetapir Positron emission tomography
Cholinesterase inhibitors Memantine

What is:

PET - _____________________________

FDA - _____________________________

Listen to the text(3:03-4:56) and fill the gaps:

The PET device makes _________ or images that doctors can read.
Florbetapir can ________up beta-amyloid and show it on the images and it
_________ with plaques in the brain.
One condition is for the manufacturer to show evidence that florbetapir correctly
__________ plaques. The other condition is that the manufacturer prepare a
__________ program for experts in ___________ medicine.

Find missing words in text


People ________ get at least temporary medical help.

But treatment ________ slow its progress.

Large amounts of this protein _______ destroy a person’s ability to think.

What do we call them?

certain uncertain
Make up sentences using may, might, can

Where’s Helen?

(at office) ________________________________________

(busy) ___________________________________________

(shopping) _______________________________________

(ill) _____________________________________________

(want to be alone) _________________________________

Answer using may/might/can:

Where do you want to go on holiday?

What will you have for dinner tonight?

What book will you read next?

What will you do this weekend?

What will you do on your way home?

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