NON MODIFIABLE MODIFIABLE

Failure of Embryonic Development Exogenous Sex Hormones

Maternal Polyhydramious Maternal Smoking and Alcohol Consumption
Exposure to Methimazole
Prolonged Mechanical Ventilation via Endo
tracheal or Tracheotomy Tube
1st Semester Exposure to DM

Upper Part of esophagus is developed from

retropharyngeal segment and the lower part of
the first part of primitive gut.

At 4-5 weeks of gestation the laryngeal tracheal

groove is formed.

Two longitudinal furrows develop and separate

the respiratory tract permordium from esophagus

Deviation cellular growth of the septum results in

formation of fistula between esophagus and
trachea

Excessive Amount of Intermittent Cyanosis

secretions

Inability to pass the

Abdominal catheter through nose Cough and
Distention Chokes